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Rottlerin, a Novel Protein Kinase Inhibitor

Biochemical and biophysical research communications, 1994-02, Vol.199 (1), p.93-98

1994

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Differential effects of suramin on protein kinase C isoenzymes. A novel tool for discriminating protein kinase C activities

FEBS letters, 1998-01, Vol.421 (2), p.165-168

1998

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Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes

FEBS letters, 1996-08, Vol.392 (2), p.77-80

1996

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Inhibition of the calcium- and phospholipid-dependent protein kinase activity from mouse brain cytosol by quercetin

Biochemical and biophysical research communications, 1983-12, Vol.117 (2), p.444-447

1983

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Protein Kinase Cδ Accepts GTP for Autophosphorylation

Biochemical and biophysical research communications, 1995-01, Vol.206 (2), p.614-620

1995

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Protein Kinase C Forms a Complex with and Phosphorylates the GTPase Activating Protein Gap:: Phosphorylation by PKC Is Dependent on Tyrosine Phosphorylation of GAP and/or a GAP-Associated Protein

Biochemical and biophysical research communications, 1993-07, Vol.194 (1), p.571-576

1993

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Calcium and phospholipid-dependent protein kinase activity in mouse epidermis cytosol. Stimulation by complete and incomplete tumor promoters and inhibition by various compounds

Biochemical and biophysical research communications, 1984-10, Vol.124 (1), p.63-68

1984

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Colon carcinoma cells use different mechanisms to escape CD95-mediated apoptosis

Cancer research (Chicago, Ill.), 1998-02, Vol.58 (3), p.526-534

1998

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The mouse ear edema: A quantitatively evaluable assay for tumor promoting compounds and for inhibitors of tumor promotion

Cancer letters, 1984-12, Vol.25 (2), p.177-185

1984

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Bryostatin 1, an activator of protein kinase C, mimics as well as inhibits biological effects of the phorbol ester TPA in vivo and in vitro

Carcinogenesis (New York), 1988-04, Vol.9 (4), p.555-562

1988

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Tyrosine phosphorylation and stimulation of protein kinase Cδ from porcine spleen by src in vitro: Dependence on the activated state of protein kinase Cδ

FEBS letters, 1994-06, Vol.347 (1), p.85-89

1994

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Lack of an effect of novel inhibitors with high specificity for protein kinase C on the action of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate on mouse skin in vivo

Carcinogenesis (New York), 1995-01, Vol.16 (1), p.107-111

1995

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A phorbol ester and phospholipid-activated, calcium-unresponsive protein kinase in mouse epidermis: Characterization and separation from protein kinase C

Journal of cellular biochemistry, 1989-07, Vol.40 (3), p.295-307

1989

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Elongation factor-2 kinase: effective inhibition by the novel protein kinase inhibitor rottlerin and relative insensitivity towards staurosporine

FEBS letters, 1994-01, Vol.338 (1), p.85-88

1994

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Protein kinase C activation by phorbol esters: do cysteine-rich regions and pseudosubstrate motifs play a role?

Trends in biochemical sciences (Amsterdam. Regular ed.), 1991, Vol.16 (5), p.167-169

1991

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A novel type of phorbol ester-dependent protein phosphorylation in the particulate fraction of mouse epidermis

Biochemical and biophysical research communications, 1986-06, Vol.137 (2), p.766-774

1986

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Effect of tumor promoting phorbol ester TPA on epidermal protein synthesis: Stimulation of an elongation factor 2 phosphatase activity by TPA in vivo

Biochemical and biophysical research communications, 1988-06, Vol.153 (3), p.1129-1135

1988

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Proteolytic cleavage of protein kinase Cμ upon induction of apoptosis in U937 cells: Identification of the cleavage site and characterization of the fragment

FEBS letters, 1999-12, Vol.462 (3), p.442-446

1999

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Cyclosporin a inhibits biological effects of tumor promoting phorbol esters

Biochemical and biophysical research communications, 1985-01, Vol.126 (1), p.327-332

1985

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Generation of the arachidonic acid metabolite 8-HETE by extracts of mouse skin treated with phorbol ester in vivo; identification by H-N.M.R. and GC-MS spectroscopy

Carcinogenesis (New York), 1986-01, Vol.7 (3), p.449-455

1986

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Sequence similarity between cyclophilin and elongation factor 2

Biochemical journal, 1988-12, Vol.256 (3), p.1061-1061

1988

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Cyclosporine A suppresses an early process in phorbol ester action

Cancer letters, 1989-07, Vol.46 (2), p.113-115

1989

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The weak immunosuppressant cyclosporine D as well as the immunologically inactive cyclosporine H are potent inhibitors in vivo of phorbol ester TPA-induced biological effects in mouse skin and of Ca2+/calmodulin dependent EF-2 phosphorylation in vitro

Biochemical and biophysical research communications, 1988-01, Vol.150 (2), p.545-551

1988

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Soluble phorbol ester binding sites in cytosol of chick liver and brain — Activation by phosphatidylserine

Cancer letters, 1983-06, Vol.19 (2), p.159-164

1983

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Stimulation of alkaline phosphatase activity in mouse epidermis by tumor promoters

Cancer letters, 1984-03, Vol.22 (2), p.219-225

1984

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Rottlerin, a Novel Protein Kinase Inhibitor

Differential effects of suramin on protein kinase C isoenzymes. A novel tool for discriminating protein kinase C activities

Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes

Inhibition of the calcium- and phospholipid-dependent protein kinase activity from mouse brain cytosol by quercetin

Protein Kinase Cδ Accepts GTP for Autophosphorylation

Protein Kinase C Forms a Complex with and Phosphorylates the GTPase Activating Protein Gap:: Phosphorylation by PKC Is Dependent on Tyrosine Phosphorylation of GAP and/or a GAP-Associated Protein

Calcium and phospholipid-dependent protein kinase activity in mouse epidermis cytosol. Stimulation by complete and incomplete tumor promoters and inhibition by various compounds

Colon carcinoma cells use different mechanisms to escape CD95-mediated apoptosis

The mouse ear edema: A quantitatively evaluable assay for tumor promoting compounds and for inhibitors of tumor promotion

Bryostatin 1, an activator of protein kinase C, mimics as well as inhibits biological effects of the phorbol ester TPA in vivo and in vitro

Tyrosine phosphorylation and stimulation of protein kinase Cδ from porcine spleen by src in vitro: Dependence on the activated state of protein kinase Cδ

Lack of an effect of novel inhibitors with high specificity for protein kinase C on the action of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate on mouse skin in vivo

A phorbol ester and phospholipid-activated, calcium-unresponsive protein kinase in mouse epidermis: Characterization and separation from protein kinase C

Elongation factor-2 kinase: effective inhibition by the novel protein kinase inhibitor rottlerin and relative insensitivity towards staurosporine

Protein kinase C activation by phorbol esters: do cysteine-rich regions and pseudosubstrate motifs play a role?

A novel type of phorbol ester-dependent protein phosphorylation in the particulate fraction of mouse epidermis

Effect of tumor promoting phorbol ester TPA on epidermal protein synthesis: Stimulation of an elongation factor 2 phosphatase activity by TPA in vivo

Proteolytic cleavage of protein kinase Cμ upon induction of apoptosis in U937 cells: Identification of the cleavage site and characterization of the fragment

Cyclosporin a inhibits biological effects of tumor promoting phorbol esters

Generation of the arachidonic acid metabolite 8-HETE by extracts of mouse skin treated with phorbol ester in vivo; identification by H-N.M.R. and GC-MS spectroscopy

Sequence similarity between cyclophilin and elongation factor 2

Cyclosporine A suppresses an early process in phorbol ester action

The weak immunosuppressant cyclosporine D as well as the immunologically inactive cyclosporine H are potent inhibitors in vivo of phorbol ester TPA-induced biological effects in mouse skin and of Ca2+/calmodulin dependent EF-2 phosphorylation in vitro

Soluble phorbol ester binding sites in cytosol of chick liver and brain — Activation by phosphatidylserine

Stimulation of alkaline phosphatase activity in mouse epidermis by tumor promoters

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