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Practical Method for Preparing Nanosuspension Formulations for Toxicology Studies in the Discovery Stage: Formulation Optimization and in Vitro/in Vivo Evaluation of Nanosized Poorly Water-Soluble Compounds

Chemical and Pharmaceutical Bulletin, 2014/11/01, Vol.62(11), pp.1073-1082

2014

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Pharmacological characterization of MP‐412 (AV‐412), a dual epidermal growth factor receptor and ErbB2 tyrosine kinase inhibitor

Cancer science, 2007-12, Vol.98 (12), p.1977-1984

2007

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Nanosuspension formulations of poorly water-soluble compounds for intravenous administration in exploratory toxicity studies: in vitro and in vivo evaluation

Journal of applied toxicology, 2016-10, Vol.36 (10), p.1259-1267

2016

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Practical Method for Preparing Nanosuspension Formulations for Toxicology Studies in the Discovery Stage

Chemical & pharmaceutical bulletin, 2014-11, Vol.62 (11), p.1073-1073

2014

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Synthesis and inhibitory activity of 4-alkynyl and 4-alkenylquinazolines: Identification of new scaffolds for potent EGFR tyrosine kinase inhibitors

Bioorganic & medicinal chemistry letters, 2007-11, Vol.17 (21), p.5863-5867

2007

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In Vitro Selection of a Peptide Inhibitor of Human IL-6 Using mRNA Display

Molecular biotechnology, 2011-06, Vol.48 (2), p.147-155

2011

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A Highly Efficient Synthesis of Prostaglandin ω-Chain Precursors

Chemistry letters, 1987-08, Vol.16 (8), p.1523-1526

1987

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A New Method for the Synthesis of Protected Chiral 4-Hydroxy-2-cyclopentenone

Chemistry letters, 1989-12, Vol.18 (12), p.2163-2164

1989

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Preparation of optically active 2-furylcarbinols by kinetic resolution using the Sharpless reagent and their application in organic synthesis

Journal of organic chemistry, 1989-04, Vol.54 (9), p.2085-2091

1989

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STEREOCONTROLLED SYNTHESIS OF SEGMENTS FOR THE SYNTHESIS OF TYLONOLIDE BY USING A RELATIVE 1,2-ASYMMETRIC INDUCTION

Chemistry letters, 1986-04, Vol.15 (4), p.523-526

1986

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A highly efficient kinetic resolution of γ- and β- trimethylsilyl secondary allylic alcohols by the sharpless asymmetric epoxidation

Tetrahedron, 1988, Vol.44 (13), p.4073-4086

1988

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Total Synthesis of Sarcophytol A, an Anticarcinogenic Marine Cembranoid

Journal of organic chemistry, 1994-05, Vol.59 (10), p.2700-2706

1994

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Preparation of optically active 2-furylcarbinols by kinetic resolution using the Sharpless reagent

Journal of organic chemistry, 1988-04, Vol.53 (7), p.1586-1587

1988

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A practical, efficient method for preparation of four possible stereoisomers of secondary allylic alcohols using kinetic resolution of (E)-1-trimethylsilylalk-1-en-3-ol by the Sharpless process

Journal of the Chemical Society. Chemical communications, 1986 (17), p.1323-1325

1986

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Acyclic stereoselection using 1,2-asymmetric induction. The first total synthesis of (+)-corynomycolic acid

Journal of the Chemical Society. Chemical communications, 1985 (8), p.498-499

1985

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Stereo- and enantioselective total synthesis of sarcophytol-A

Tetrahedron letters, 1990, Vol.31 (23), p.3317-3320

1990

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Diastereo- and enantioselective preparation of β-alkylhomoallylic alcohols : Synthesis of serricornin and corynomycolic acid

Tetrahedron, 1986, Vol.42 (11), p.2937-2943

1986

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Preparation of optically active 2-thienylcarbinols by kinetic resolution using the Sharpless reagent

Journal of organic chemistry, 1989-02, Vol.54 (4), p.994-996

1989

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A highly efficient synthesis of optically pure γ-iodo allylic alcohols and their conversion into various optically active allylic alcohols

Tetrahedron letters, 1987, Vol.28 (50), p.6351-6354

1987

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Enantioselective synthesis of 1-vinyl-1,2-diols, vinyl epoxides and α,β-dialkoxy aldehydes

Tetrahedron letters, 1988, Vol.29 (44), p.5685-5688

1988

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Diastereo- and enantioselective preparation of β-alkylhomoallylic alcohols

Tetrahedron, 1986-01, Vol.42 (11), p.2937-2943

1986

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A practical method for multigram scale synthesis of (+)-methyl 5(S),6(R)-epoxy-6-formylhexanoate and 2(R),3(S)-epoxyoctanal, key intermediates for synthesis of leukotrienes A 4

Tetrahedron letters, 1986, Vol.27 (39), p.4775-4778

1986

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A practical method for multigram scale synthesis of (+)-methyl 5(S), 6(R)-epoxy-6-formylhexanoate and 2(R),3(S)-epoxyoctanal, key intermediates for synthesis of leukotrienes A4

Tetrahedron letters, 1986, Vol.27 (39), p.4775-4778

1986

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A Highly Efficient Synthesis of Prostaglandin [omega]-Chain Precursors

Chemistry letters, 1987-08, Vol.16 (8), p.1523

1987

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An information theory approach to production smoothing with stochastic demands. An application of rate-distortion function

International journal of systems science, 1977-03, Vol.8 (3), p.263-271

1977

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Practical Method for Preparing Nanosuspension Formulations for Toxicology Studies in the Discovery Stage: Formulation Optimization and in Vitro/in Vivo Evaluation of Nanosized Poorly Water-Soluble Compounds

Pharmacological characterization of MP‐412 (AV‐412), a dual epidermal growth factor receptor and ErbB2 tyrosine kinase inhibitor

Nanosuspension formulations of poorly water-soluble compounds for intravenous administration in exploratory toxicity studies: in vitro and in vivo evaluation

Practical Method for Preparing Nanosuspension Formulations for Toxicology Studies in the Discovery Stage

Synthesis and inhibitory activity of 4-alkynyl and 4-alkenylquinazolines: Identification of new scaffolds for potent EGFR tyrosine kinase inhibitors

In Vitro Selection of a Peptide Inhibitor of Human IL-6 Using mRNA Display

A Highly Efficient Synthesis of Prostaglandin ω-Chain Precursors

A New Method for the Synthesis of Protected Chiral 4-Hydroxy-2-cyclopentenone

Preparation of optically active 2-furylcarbinols by kinetic resolution using the Sharpless reagent and their application in organic synthesis

STEREOCONTROLLED SYNTHESIS OF SEGMENTS FOR THE SYNTHESIS OF TYLONOLIDE BY USING A RELATIVE 1,2-ASYMMETRIC INDUCTION

A highly efficient kinetic resolution of γ- and β- trimethylsilyl secondary allylic alcohols by the sharpless asymmetric epoxidation

Total Synthesis of Sarcophytol A, an Anticarcinogenic Marine Cembranoid

Preparation of optically active 2-furylcarbinols by kinetic resolution using the Sharpless reagent

A practical, efficient method for preparation of four possible stereoisomers of secondary allylic alcohols using kinetic resolution of (E)-1-trimethylsilylalk-1-en-3-ol by the Sharpless process

Acyclic stereoselection using 1,2-asymmetric induction. The first total synthesis of (+)-corynomycolic acid

Stereo- and enantioselective total synthesis of sarcophytol-A

Diastereo- and enantioselective preparation of β-alkylhomoallylic alcohols : Synthesis of serricornin and corynomycolic acid

Preparation of optically active 2-thienylcarbinols by kinetic resolution using the Sharpless reagent

A highly efficient synthesis of optically pure γ-iodo allylic alcohols and their conversion into various optically active allylic alcohols

Enantioselective synthesis of 1-vinyl-1,2-diols, vinyl epoxides and α,β-dialkoxy aldehydes

Diastereo- and enantioselective preparation of β-alkylhomoallylic alcohols

A practical method for multigram scale synthesis of (+)-methyl 5(S),6(R)-epoxy-6-formylhexanoate and 2(R),3(S)-epoxyoctanal, key intermediates for synthesis of leukotrienes A 4

A practical method for multigram scale synthesis of (+)-methyl 5(S), 6(R)-epoxy-6-formylhexanoate and 2(R),3(S)-epoxyoctanal, key intermediates for synthesis of leukotrienes A4

A Highly Efficient Synthesis of Prostaglandin [omega]-Chain Precursors

An information theory approach to production smoothing with stochastic demands. An application of rate-distortion function

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