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Function-specific IL-17A and dexamethasone interactions in primary human airway epithelial cells

Scientific reports, 2022-06, Vol.12 (1), p.11110-13, Article 11110

2022

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Reduced Vitamin K Status as a Potentially Modifiable Risk Factor of Severe Coronavirus Disease 2019

Clinical infectious diseases, 2021-12, Vol.73 (11), p.e4039-e4046

2021

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Combination therapy of tiotropium and ciclesonide attenuates airway inflammation and remodeling in a guinea pig model of chronic asthma

Respiratory research, 2016-02, Vol.17 (14), p.13-13, Article 13

2016

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The novel TRPA1 antagonist BI01305834 inhibits ovalbumin-induced bronchoconstriction in guinea pigs

Respiratory research, 2021-02, Vol.22 (1), p.48-48, Article 48

2021

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A new perspective on muscarinic receptor antagonism in obstructive airways diseases

Current opinion in pharmacology, 2013-06, Vol.13 (3), p.316-323

2013

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Muscarinic receptor subtype-specific effects on cigarette smoke-induced inflammation in mice

The European respiratory journal, 2013-12, Vol.42 (6), p.1677-1688

2013

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HDAC1-3 inhibitor MS-275 enhances IL10 expression in RAW264.7 macrophages and reduces cigarette smoke-induced airway inflammation in mice

Scientific reports, 2017-03, Vol.7 (1), p.45047, Article 45047

2017

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Acetylcholine beyond bronchoconstriction: roles in inflammation and remodeling

Trends in pharmacological sciences (Regular ed.), 2015-03, Vol.36 (3), p.164-171

2015

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Anti-inflammatory effects of targeted lung denervation in patients with COPD

The European respiratory journal, 2015-11, Vol.46 (5), p.1489-1492

2015

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Rho-Kinase 1/2 Inhibition Prevents Transforming Growth Factor-β-Induced Effects on Pulmonary Remodeling and Repair

Frontiers in pharmacology, 2021-01, Vol.11, p.609509-609509

2021

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Mesenchymal WNT-5A/5B Signaling Represses Lung Alveolar Epithelial Progenitors

Cells (Basel, Switzerland), 2019-09, Vol.8 (10), p.1147

2019

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Cigarette smoke differentially affects IL‐13‐induced gene expression in human airway epithelial cells

Physiological reports, 2017-07, Vol.5 (13), p.e13347-n/a

2017

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Cigarette smoke up‐regulates PDE3 and PDE4 to decrease cAMP in airway cells

British journal of pharmacology, 2018-07, Vol.175 (14), p.2988-3006

2018

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HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity

Biochemical pharmacology, 2016-05, Vol.108, p.58-74

2016

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Diesel exhaust particles distort lung epithelial progenitors and their fibroblast niche

Environmental pollution (1987), 2022-07, Vol.305, p.119292-119292, Article 119292

2022

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Regulation of airway inflammation and remodeling by muscarinic receptors: Perspectives on anticholinergic therapy in asthma and COPD

Life sciences (1973), 2012-11, Vol.91 (21-22), p.1126-1133

2012

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PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells

Respiratory research, 2009-09, Vol.10 (1), p.88-88, Article 88

2009

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Tiotropium attenuates IL-13-induced goblet cell metaplasia of human airway epithelial cells

Thorax, 2015-07, Vol.70 (7), p.668-676

2015

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Cholinergic neuroplasticity in asthma driven by TrkB signaling

The FASEB journal, 2020-06, Vol.34 (6), p.7703-7717

2020

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Airway smooth muscle in asthma: Linking contraction and mechanotransduction to disease pathogenesis and remodelling

Pulmonary pharmacology & therapeutics, 2014-12, Vol.29 (2), p.96-107

2014

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Second M 3 muscarinic receptor binding site contributes to bronchoprotection by tiotropium

British journal of pharmacology, 2019-08, Vol.176 (16), p.2864-2876

2019

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The PDE4 inhibitor CHF-6001 and LAMAs inhibit bronchoconstriction-induced remodeling in lung slices

American journal of physiology. Lung cellular and molecular physiology, 2017-09, Vol.313 (3), p.L507-L515

2017

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A transcriptomics-guided drug target discovery strategy identifies receptor ligands for lung regeneration

Science advances, 2022-03, Vol.8 (12), p.eabj9949

2022

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Muscarinic M3 receptors on structural cells regulate cigarette smoke-induced neutrophilic airway inflammation in mice

American journal of physiology. Lung cellular and molecular physiology, 2015-01, Vol.308 (1), p.L96-103

2015

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Second M3 muscarinic receptor binding site contributes to bronchoprotection by tiotropium

British journal of pharmacology, 2019-08, Vol.176 (16), p.2864-2876

2019

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Gene Expression
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Function-specific IL-17A and dexamethasone interactions in primary human airway epithelial cells

Reduced Vitamin K Status as a Potentially Modifiable Risk Factor of Severe Coronavirus Disease 2019

Combination therapy of tiotropium and ciclesonide attenuates airway inflammation and remodeling in a guinea pig model of chronic asthma

The novel TRPA1 antagonist BI01305834 inhibits ovalbumin-induced bronchoconstriction in guinea pigs

A new perspective on muscarinic receptor antagonism in obstructive airways diseases

Muscarinic receptor subtype-specific effects on cigarette smoke-induced inflammation in mice

HDAC1-3 inhibitor MS-275 enhances IL10 expression in RAW264.7 macrophages and reduces cigarette smoke-induced airway inflammation in mice

Acetylcholine beyond bronchoconstriction: roles in inflammation and remodeling

Anti-inflammatory effects of targeted lung denervation in patients with COPD

Rho-Kinase 1/2 Inhibition Prevents Transforming Growth Factor-β-Induced Effects on Pulmonary Remodeling and Repair

Mesenchymal WNT-5A/5B Signaling Represses Lung Alveolar Epithelial Progenitors

Cigarette smoke differentially affects IL‐13‐induced gene expression in human airway epithelial cells

Cigarette smoke up‐regulates PDE3 and PDE4 to decrease cAMP in airway cells

HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity

Diesel exhaust particles distort lung epithelial progenitors and their fibroblast niche

Regulation of airway inflammation and remodeling by muscarinic receptors: Perspectives on anticholinergic therapy in asthma and COPD

PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells

Tiotropium attenuates IL-13-induced goblet cell metaplasia of human airway epithelial cells

Cholinergic neuroplasticity in asthma driven by TrkB signaling

Airway smooth muscle in asthma: Linking contraction and mechanotransduction to disease pathogenesis and remodelling

Second M 3 muscarinic receptor binding site contributes to bronchoprotection by tiotropium

The PDE4 inhibitor CHF-6001 and LAMAs inhibit bronchoconstriction-induced remodeling in lung slices

A transcriptomics-guided drug target discovery strategy identifies receptor ligands for lung regeneration

Muscarinic M3 receptors on structural cells regulate cigarette smoke-induced neutrophilic airway inflammation in mice

Second M3 muscarinic receptor binding site contributes to bronchoprotection by tiotropium

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