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10-Propargylaminopterin and alkyl homologs of methotrexate as inhibitors of folate metabolism

Journal of medicinal chemistry, 1982-07, Vol.25 (7), p.877-880

1982

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10-Propargylaminopterin and alkyl homologues of methotrexate as inhibitors of folate metabolism

Journal of medicinal chemistry, 1982-07, Vol.25 (7), p.877-880

1982

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[180] Synthesis and assay of tetrahydrohomofolic acid and tetrahydrohomopteroic acid

Methods in Enzymology, 1971, Vol.18, p.663-670

Kisliuk, R.L.

1971

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19F NMR studies of the binding of 5-fluoro-2'-deoxyuridylate to thymidylate synthase

Molecular and cellular biochemistry, 1980-08, Vol.32 (1), p.45-48

1980

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2,4-Diamino-5-deaza-6-Substituted Pyrido[2,3-d]pyrimidine Antifolates as Potent and Selective Nonclassical Inhibitors of Dihydrofolate Reductases

Journal of medicinal chemistry, 1996-03, Vol.39 (7), p.1438-1446

1996

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2,4-Diamino-5-deaza-6-Substituted Pyrido[2,3-d]pyrimidine Antifolates as Potent and Selective Nonclassical Inhibitors of Dihydrofolate Reductases

Journal of medicinal chemistry, 1996-08, Vol.39 (16), p.3228-3228

1996

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2,4-Diamino-5-methyl-6-substituted arylthio-furo[2,3- d]pyrimidines as novel classical and nonclassical antifolates as potential dual thymidylate synthase and dihydrofolate reductase inhibitors

Bioorganic & medicinal chemistry, 2010-01, Vol.18 (2), p.953-961

2010

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2,4-Diamino-5-methyl-6-substituted Arylthio-furo[2,3-d]pyrimidines as Novel Classical and Nonclassical Antifolates as Potential Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors1a,b

Bioorganic & medicinal chemistry, 2009-12, Vol.18 (2), p.953

2009

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2,4-Diamino-6-arylethylpteridines as Streptococcus faecium growth inhibitors

Journal of medicinal chemistry, 1971-09, Vol.14 (9), p.866-867

1971

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2-Amino-4-hydroxy-6-arylaminoethylpteridines as potential antimalarial agents

Journal of medicinal chemistry, 1971-03, Vol.14 (3), p.206-210

1971

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2-Amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines as nonclassical antifolate inhibitors of thymidylate synthase

Journal of medicinal chemistry, 1996-11, Vol.39 (23), p.4563-4568

1996

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2-Amino-4-oxo-5-substituted-pyrrolo[2,3- d ]pyrimidines as Nonclassical Antifolate Inhibitors of Thymidylate Synthase 1a,b

Journal of medicinal chemistry, 1996-01, Vol.39 (23), p.4563-4568

1996

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2-Amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines as Nonclassical Antifolate Inhibitors of Thymidylate Synthase1a,b

Journal of medicinal chemistry, 1996-11, Vol.39 (23), p.4563-4568

1996

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2-Amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines as Nonclassical Antifolate Inhibitors of Thymidylate Synthase

Journal of medicinal chemistry, 1997-02, Vol.40 (4), p.632-632

1997

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2-amino-4-oxo-6-substituted-pyrrolo[2,3-d]pynmidines as potential inhibitors of thymidylate synthase

Journal of heterocyclic chemistry, 2002-07, Vol.39 (4), p.833-840

2002

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2-Amino-4-oxo-6-substituted-pyrrolo[2,3-d]pyrimidines as Potential Inhibitors of Thymidylate Synthase

ChemInform, 2002-12, Vol.33 (52), p.146-146

2002

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3'-Iodo-4-amino-4-deoxypteroylglutamic Acid (3'-Iodoaminopterin)

Journal of medicinal chemistry, 1965-09, Vol.8 (5), p.713-715

1965

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31P NMR studies on the interaction of deoxyuridylate with thymidylate synthase

Biochimica et biophysica acta, 1979-11, Vol.571 (1), p.157

1979

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31P NMR studies on the interaction of deoxyuridylate with thymidylate synthase

BBA - Enzymology, 1979-11, Vol.571 (1), p.157-161

1979

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5,10-Methylenetetrahydro-5-deazafolic acid and analogs: synthesis and biological activities

Journal of medicinal chemistry, 1992-10, Vol.35 (20), p.3678-3685

1992

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5-Arylthio Substituted 2-Amino-4-oxo-6-methylpyrrolo[2,3-d]pyrimidine Antifolates as Thymidylate Synthase Inhibitors and Antitumor Agents

Journal of medicinal chemistry, 1995-10, Vol.38 (22), p.4495-4502

1995

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6-Substituted 2,4-Diamino-5-methylpyrido[2,3-d]pyrimidines as Inhibitors of Dihydrofolate Reductases from Pneumocystis carinii and Toxoplasma gondii and as Antitumor Agents

Journal of medicinal chemistry, 1995-05, Vol.38 (10), p.1778-1785

1995

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Absolute configuration of biological tetrahydrofolates. A crystallographic determination

Journal of the American Chemical Society, 1979-09, Vol.101 (20), p.6114-6115

1979

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Abstract 1367: Substituted Pyrimido[4,5- b ]indoles with single agent combination chemotherapeutic potential

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.1367-1367

2011

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Abstract 3250: Design, synthesis and biological evaluation of side chain pemetrexed (PMX) analogues as potent inhibitors of tumors expressing folate receptors via GARFTase inhibition

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.3250-3250

2011

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10-Propargylaminopterin and alkyl homologs of methotrexate as inhibitors of folate metabolism

10-Propargylaminopterin and alkyl homologues of methotrexate as inhibitors of folate metabolism

[180] Synthesis and assay of tetrahydrohomofolic acid and tetrahydrohomopteroic acid

19F NMR studies of the binding of 5-fluoro-2'-deoxyuridylate to thymidylate synthase

2,4-Diamino-5-deaza-6-Substituted Pyrido[2,3-d]pyrimidine Antifolates as Potent and Selective Nonclassical Inhibitors of Dihydrofolate Reductases

2,4-Diamino-5-deaza-6-Substituted Pyrido[2,3-d]pyrimidine Antifolates as Potent and Selective Nonclassical Inhibitors of Dihydrofolate Reductases

2,4-Diamino-5-methyl-6-substituted arylthio-furo[2,3- d]pyrimidines as novel classical and nonclassical antifolates as potential dual thymidylate synthase and dihydrofolate reductase inhibitors

2,4-Diamino-5-methyl-6-substituted Arylthio-furo[2,3-d]pyrimidines as Novel Classical and Nonclassical Antifolates as Potential Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors1a,b

2,4-Diamino-6-arylethylpteridines as Streptococcus faecium growth inhibitors

2-Amino-4-hydroxy-6-arylaminoethylpteridines as potential antimalarial agents

2-Amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines as nonclassical antifolate inhibitors of thymidylate synthase

2-Amino-4-oxo-5-substituted-pyrrolo[2,3- d ]pyrimidines as Nonclassical Antifolate Inhibitors of Thymidylate Synthase 1a,b

2-Amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines as Nonclassical Antifolate Inhibitors of Thymidylate Synthase1a,b

2-Amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines as Nonclassical Antifolate Inhibitors of Thymidylate Synthase

2-amino-4-oxo-6-substituted-pyrrolo[2,3-d]pynmidines as potential inhibitors of thymidylate synthase

2-Amino-4-oxo-6-substituted-pyrrolo[2,3-d]pyrimidines as Potential Inhibitors of Thymidylate Synthase

3'-Iodo-4-amino-4-deoxypteroylglutamic Acid (3'-Iodoaminopterin)

31P NMR studies on the interaction of deoxyuridylate with thymidylate synthase

31P NMR studies on the interaction of deoxyuridylate with thymidylate synthase

5,10-Methylenetetrahydro-5-deazafolic acid and analogs: synthesis and biological activities

5-Arylthio Substituted 2-Amino-4-oxo-6-methylpyrrolo[2,3-d]pyrimidine Antifolates as Thymidylate Synthase Inhibitors and Antitumor Agents

6-Substituted 2,4-Diamino-5-methylpyrido[2,3-d]pyrimidines as Inhibitors of Dihydrofolate Reductases from Pneumocystis carinii and Toxoplasma gondii and as Antitumor Agents

Absolute configuration of biological tetrahydrofolates. A crystallographic determination

Abstract 1367: Substituted Pyrimido[4,5- b ]indoles with single agent combination chemotherapeutic potential

Abstract 3250: Design, synthesis and biological evaluation of side chain pemetrexed (PMX) analogues as potent inhibitors of tumors expressing folate receptors via GARFTase inhibition

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