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Mutations in Regulatory Subunit Type 1A of Cyclic Adenosine 5′-Monophosphate-Dependent Protein Kinase (PRKAR1A): Phenotype Analysis in 353 Patients and 80 Different Genotypes

The journal of clinical endocrinology and metabolism, 2009-06, Vol.94 (6), p.2085-2091

2009

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PRKAR1A and the evolution of pituitary tumors

Molecular and cellular endocrinology, 2010-09, Vol.326 (1), p.3-7

Kirschner, Lawrence S.

2010

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PKA Activates AMPK Through LKB1 Signaling in Follicular Thyroid Cancer

Frontiers in endocrinology (Lausanne), 2019-11, Vol.10, p.769-769

2019

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Snapin Mediates Incretin Action and Augments Glucose-Dependent Insulin Secretion

Cell metabolism, 2011-03, Vol.13 (3), p.308-319

2011

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Cushing's syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice

PLoS genetics, 2010-06, Vol.6 (6), p.e1000980-e1000980

2010

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Predictors of Postoperative Diabetes Insipidus Following Endoscopic Resection of Pituitary Adenomas

Journal of the Endocrine Society, 2018-09, Vol.2 (9), p.1010-1019

2018

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Papillary Thyroid Carcinoma: Association Between Germline DNA Variant Markers and Clinical Parameters

Thyroid (New York, N.Y.), 2016-09, Vol.26 (9), p.1276

2016

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Protein kinase A activation enhances β-catenin transcriptional activity through nuclear localization to PML bodies

PloS one, 2014-10, Vol.9 (10), p.e109523

2014

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Follicular Thyroid Cancers Demonstrate Dual Activation of PKA and mTOR as Modeled by Thyroid-Specific Deletion of Prkar1a and Pten in Mice

The journal of clinical endocrinology and metabolism, 2014-05, Vol.99 (5), p.E804-E812

2014

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Mouse models of altered protein kinase A signaling

Endocrine-related cancer, 2009-09, Vol.16 (3), p.773-793

2009

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Abnormal Fibroblasts Drive Pigmentary Skin Lesions in a Mouse Model of Carney Complex

Journal of investigative dermatology, 2022-11, Vol.142 (11), p.2850-2852

2022

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A mouse model for the carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues

Cancer research (Chicago, Ill.), 2005-06, Vol.65 (11), p.4506-4514

2005

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Regulation of actin function by protein kinase A-mediated phosphorylation of Limk1

EMBO reports, 2009-06, Vol.10 (6), p.599-605

2009

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PRKAR1A deficiency impedes hypertrophy and reduces heart size

Physiological reports, 2020-03, Vol.8 (6), p.e14405-n/a

2020

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Differential Role of PKA Catalytic Subunits in Mediating Phenotypes Caused by Knockout of the Carney Complex Gene Prkar1a

Molecular endocrinology (Baltimore, Md.), 2011-10, Vol.25 (10), p.1786-1793

2011

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2-Amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} Acetamide (OSU-03012), a Celecoxib Derivative, Directly Targets p21-Activated Kinase

Molecular pharmacology, 2007-11, Vol.72 (5), p.1124-1131

2007

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Case report: ACTH-secreting pituitary carcinoma metastatic to the liver in a patient with a history of atypical pituitary adenoma and Cushing's disease

Diagnostic pathology, 2017-04, Vol.12 (1), p.34-34, Article 34

2017

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Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone

Proceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (19), p.8683-8688

2010

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A unified cause for adrenal Cushing's syndrome

Science (American Association for the Advancement of Science), 2014-05, Vol.344 (6186), p.804-805

Kirschner, Lawrence S.

2014

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Nivolumab in Metastatic Adrenocortical Carcinoma: Results of a Phase 2 Trial

The journal of clinical endocrinology and metabolism, 2019-12, Vol.104 (12), p.6193-6200

2019

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Gene array analysis of macronodular adrenal hyperplasia confirms clinical heterogeneity and identifies several candidate genes as molecular mediators

Oncogene, 2004-02, Vol.23 (8), p.1575-1585

2004

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Inhibition of IGF-1R in adrenocortical carcinoma

The lancet oncology, 2015-04, Vol.16 (4), p.356-357

Kirschner, Lawrence S

2015

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Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors

Cancer research (Chicago, Ill.), 2004-12, Vol.64 (24), p.8811-8815

2004

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The next generation of therapies for adrenocortical cancers

Trends in endocrinology and metabolism, 2012-07, Vol.23 (7), p.343-350

Kirschner, Lawrence S

2012

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Deletion of Rap1b, but not Rap1a or Epac1, Reduces Protein Kinase A-Mediated Thyroid Cancer

Thyroid (New York, N.Y.), 2018-09, Vol.28 (9), p.1153

2018

Volltextzugriff (PDF)

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Mutations in Regulatory Subunit Type 1A of Cyclic Adenosine 5′-Monophosphate-Dependent Protein Kinase (PRKAR1A): Phenotype Analysis in 353 Patients and 80 Different Genotypes

PRKAR1A and the evolution of pituitary tumors

PKA Activates AMPK Through LKB1 Signaling in Follicular Thyroid Cancer

Snapin Mediates Incretin Action and Augments Glucose-Dependent Insulin Secretion

Cushing's syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice

Predictors of Postoperative Diabetes Insipidus Following Endoscopic Resection of Pituitary Adenomas

Papillary Thyroid Carcinoma: Association Between Germline DNA Variant Markers and Clinical Parameters

Protein kinase A activation enhances β-catenin transcriptional activity through nuclear localization to PML bodies

Follicular Thyroid Cancers Demonstrate Dual Activation of PKA and mTOR as Modeled by Thyroid-Specific Deletion of Prkar1a and Pten in Mice

Mouse models of altered protein kinase A signaling

Abnormal Fibroblasts Drive Pigmentary Skin Lesions in a Mouse Model of Carney Complex

A mouse model for the carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues

Regulation of actin function by protein kinase A-mediated phosphorylation of Limk1

PRKAR1A deficiency impedes hypertrophy and reduces heart size

Differential Role of PKA Catalytic Subunits in Mediating Phenotypes Caused by Knockout of the Carney Complex Gene Prkar1a

2-Amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} Acetamide (OSU-03012), a Celecoxib Derivative, Directly Targets p21-Activated Kinase

Case report: ACTH-secreting pituitary carcinoma metastatic to the liver in a patient with a history of atypical pituitary adenoma and Cushing's disease

Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone

A unified cause for adrenal Cushing's syndrome

Nivolumab in Metastatic Adrenocortical Carcinoma: Results of a Phase 2 Trial

Gene array analysis of macronodular adrenal hyperplasia confirms clinical heterogeneity and identifies several candidate genes as molecular mediators

Inhibition of IGF-1R in adrenocortical carcinoma

Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors

The next generation of therapies for adrenocortical cancers

Deletion of Rap1b, but not Rap1a or Epac1, Reduces Protein Kinase A-Mediated Thyroid Cancer

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