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Evaluation of Lipopeptide (Daptomycin) Aggregation Using Fluorescence, Light Scattering, and Nuclear Magnetic Resonance Spectroscopy

Journal of pharmaceutical sciences, 2014-03, Vol.103 (3), p.853-861

2014

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A Novel Method for Assessing Drug Degradation Product Safety Using Physiologically-Based Pharmacokinetic Models and Stochastic Risk Assessment

Journal of pharmaceutical sciences, 2015-09, Vol.104 (9), p.3101-3119

2015

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The role of aggregation and ionization in the chemical instability of Amphotericin B in aqueous methanol

International journal of pharmaceutics, 2023-02, Vol.632, p.122586-122586, Article 122586

2023

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Studies on the Mechanism of Aspartic Acid Cleavage and Glutamine Deamidation in the Acidic Degradation of Glucagon

Journal of pharmaceutical sciences, 2005-09, Vol.94 (9), p.1912-1927

2005

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Glycosylation of aromatic amines III: Mechanistic implications of the pH-dependent glycosylation of various aromatic amines (kynurenine, 2′-aminoacetophenone, daptomycin, and sulfamethoxzaole)

Journal of pharmaceutical sciences, 2009-12, Vol.98 (12), p.4639-4649

2009

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Unveiling the Amphotericin B Degradation Pathway and Its Kinetics in Lipid-Based Solutions

Journal of pharmaceutical sciences, 2021-03, Vol.110 (3), p.1248-1258

2021

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Studies on the Instability of Chlorhexidine, Part I: Kinetics and Mechanisms

Journal of pharmaceutical sciences, 2012-07, Vol.101 (7), p.2417-2427

2012

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Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects

Malaria journal, 2009-12, Vol.8 (1), p.304-304, Article 304

2009

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Using Manufacturing Design Space Concepts for Stability Risk Assessment—Gabapentin NIPTE/FDA Case Study

AAPS PharmSciTech, 2018-10, Vol.19 (7), p.2801-2807

2018

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Particle Size Distribution Equivalency as Novel Predictors for Bioequivalence

AAPS PharmSciTech, 2018-10, Vol.19 (7), p.2787-2800

2018

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The Ortho Effect on the Acidic and Alkaline Hydrolysis of Substituted Formanilides

International journal of chemical kinetics, 2015-08, Vol.47 (8), p.471-488

2015

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Polymorphic and Covalent Transformations of Gabapentin in Binary Excipient Mixtures after Milling-Induced Stress

Pharmaceutical research, 2018-02, Vol.35 (2), p.39-12, Article 39

2018

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Quantification of gabapentin polymorphs in gabapentin/excipient mixtures using solid state 13 C NMR spectroscopy and X-ray powder diffraction

Journal of pharmaceutical and biomedical analysis, 2017-11, Vol.146, p.29-36

2017

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Quantification of gabapentin polymorphs in gabapentin/excipient mixtures using solid state 13C NMR spectroscopy and X-ray powder diffraction

Journal of pharmaceutical and biomedical analysis, 2017-11, Vol.146, p.29-36

2017

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Kinetic Model for Solid-State Degradation of Gabapentin

Journal of pharmaceutical sciences, 2012-06, Vol.101 (6), p.2123-2133

2012

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Estimated pKa values for specific amino acid residues in daptomycin

Journal of pharmaceutical sciences, 2011-10, Vol.100 (10), p.4225-4233

2011

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The interaction mechanism between lipopeptide (daptomycin) and polyamidoamine (PAMAM) dendrimers

Journal of peptide science, 2015-04, Vol.21 (4), p.312-319

2015

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The degradation pathways of glucagon in acidic solutions

International journal of pharmaceutics, 2000-08, Vol.203 (1), p.115-125

2000

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Characterization of seed nuclei in glucagon aggregation using light scattering methods and field-flow fractionation

Journal of biological engineering, 2008-07, Vol.2 (1), p.10-10, Article 10

2008

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The protein-binding and drug release properties of macromolecular conjugates containing daptomycin and dextran

International journal of pharmaceutics, 2006-06, Vol.315 (1), p.30-43

2006

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Diabetes and Neurodegeneration in Wolfram Syndrome: A multicenter study of phenotype and genotype

Diabetes care, 2011-07, Vol.34 (7), p.1503-1510

2011

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The Stabilizing Effect of Moisture on the Solid-State Degradation of Gabapentin

AAPS PharmSciTech, 2011-09, Vol.12 (3), p.924-931, Article 924

2011

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Glycosylation of aromatic amines II: Kinetics and mechanisms of the hydrolytic reaction between kynurenine and glucose

Journal of pharmaceutical sciences, 2009-12, Vol.98 (12), p.4616-4628

2009

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The estimation of glutaminyl deamidation and aspartyl cleavage rates in glucagon

International journal of pharmaceutics, 2004-04, Vol.273 (1), p.213-219

2004

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The Relative Rates of Glutamine and Asparagine Deamidation in Glucagon Fragment 22–29 under Acidic Conditions

Journal of pharmaceutical sciences, 2002-11, Vol.91 (11), p.2331-2345

2002

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Evaluation of Lipopeptide (Daptomycin) Aggregation Using Fluorescence, Light Scattering, and Nuclear Magnetic Resonance Spectroscopy

A Novel Method for Assessing Drug Degradation Product Safety Using Physiologically-Based Pharmacokinetic Models and Stochastic Risk Assessment

The role of aggregation and ionization in the chemical instability of Amphotericin B in aqueous methanol

Studies on the Mechanism of Aspartic Acid Cleavage and Glutamine Deamidation in the Acidic Degradation of Glucagon

Glycosylation of aromatic amines III: Mechanistic implications of the pH-dependent glycosylation of various aromatic amines (kynurenine, 2′-aminoacetophenone, daptomycin, and sulfamethoxzaole)

Unveiling the Amphotericin B Degradation Pathway and Its Kinetics in Lipid-Based Solutions

Studies on the Instability of Chlorhexidine, Part I: Kinetics and Mechanisms

Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects

Using Manufacturing Design Space Concepts for Stability Risk Assessment—Gabapentin NIPTE/FDA Case Study

Particle Size Distribution Equivalency as Novel Predictors for Bioequivalence

The Ortho Effect on the Acidic and Alkaline Hydrolysis of Substituted Formanilides

Polymorphic and Covalent Transformations of Gabapentin in Binary Excipient Mixtures after Milling-Induced Stress

Quantification of gabapentin polymorphs in gabapentin/excipient mixtures using solid state 13 C NMR spectroscopy and X-ray powder diffraction

Quantification of gabapentin polymorphs in gabapentin/excipient mixtures using solid state 13C NMR spectroscopy and X-ray powder diffraction

Kinetic Model for Solid-State Degradation of Gabapentin

Estimated pKa values for specific amino acid residues in daptomycin

The interaction mechanism between lipopeptide (daptomycin) and polyamidoamine (PAMAM) dendrimers

The degradation pathways of glucagon in acidic solutions

Characterization of seed nuclei in glucagon aggregation using light scattering methods and field-flow fractionation

The protein-binding and drug release properties of macromolecular conjugates containing daptomycin and dextran

Diabetes and Neurodegeneration in Wolfram Syndrome: A multicenter study of phenotype and genotype

The Stabilizing Effect of Moisture on the Solid-State Degradation of Gabapentin

Glycosylation of aromatic amines II: Kinetics and mechanisms of the hydrolytic reaction between kynurenine and glucose

The estimation of glutaminyl deamidation and aspartyl cleavage rates in glucagon

The Relative Rates of Glutamine and Asparagine Deamidation in Glucagon Fragment 22–29 under Acidic Conditions

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