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The malaria parasite cation ATPase PfATP4 and its role in the mechanism of action of a new arsenal of antimalarial drugs

International journal for parasitology -- drugs and drug resistance, 2015-12, Vol.5 (3), p.149-162

2015

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Membrane Transport in the Malaria-Infected Erythrocyte

Physiological reviews, 2001-04, Vol.81 (2), p.495-537

Kirk, Kiaran

2001

Volltextzugriff (PDF)

Membrane transport in the malaria parasite and its host erythrocyte

Biochemical journal, 2014-01, Vol.457 (1), p.1-18

2014

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Diverse chemotypes disrupt ion homeostasis in the malaria parasite

Molecular microbiology, 2014-10, Vol.94 (2), p.327-339

2014

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Identifying the major lactate transporter of Toxoplasma gondii tachyzoites

Scientific reports, 2021-03, Vol.11 (1), p.6787-6787, Article 6787

2021

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Chloroquine Transport via the Malaria Parasite's Chloroquine Resistance Transporter

Science (American Association for the Advancement of Science), 2009-09, Vol.325 (5948), p.1680-1682

2009

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Na+ Regulation in the Malaria Parasite Plasmodium falciparum Involves the Cation ATPase PfATP4 and Is a Target of the Spiroindolone Antimalarials

Cell host & microbe, 2013-02, Vol.13 (2), p.227-237

2013

Volltextzugriff (PDF)

Coordinated action of multiple transporters in the acquisition of essential cationic amino acids by the intracellular parasite Toxoplasma gondii

PLoS pathogens, 2021-08, Vol.17 (8), p.e1009835-e1009835

2021

Volltextzugriff (PDF)

The tyrosine transporter of Toxoplasma gondii is a member of the newly defined apicomplexan amino acid transporter (ApiAT) family

PLoS pathogens, 2019-02, Vol.15 (2), p.e1007577-e1007577

2019

Volltextzugriff (PDF)

Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites

Nature communications, 2017-02, Vol.8 (1), p.14455-14455, Article 14455

2017

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Substrate-mediated regulation of the arginine transporter of Toxoplasma gondii

PLoS pathogens, 2021-08, Vol.17 (8), p.e1009816-e1009816

2021

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A G358S mutation in the Plasmodium falciparum Na + pump PfATP4 confers clinically-relevant resistance to cipargamin

Nature communications, 2022-09, Vol.13 (1), p.5746-5746, Article 5746

2022

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Mice Deficient in the Putative Phospholipid Flippase ATP11C Exhibit Altered Erythrocyte Shape, Anemia, and Reduced Erythrocyte Life Span

The Journal of biological chemistry, 2014-07, Vol.289 (28), p.19531-19537

2014

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Diverse antimalarials from whole-cell phenotypic screens disrupt malaria parasite ion and volume homeostasis

Scientific reports, 2018-06, Vol.8 (1), p.8795-15, Article 8795

2018

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The Malaria Parasite's Lactate Transporter PfFNT Is the Target of Antiplasmodial Compounds Identified in Whole Cell Phenotypic Screens

PLoS pathogens, 2017-02, Vol.13 (2), p.e1006180-e1006180

2017

Volltextzugriff (PDF)

A female gametocyte-specific ABC transporter plays a role in lipid metabolism in the malaria parasite

Nature communications, 2014-09, Vol.5 (1), p.4773-4773, Article 4773

2014

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Chloroquine Resistance-Conferring Mutations in pfcrt Give Rise to a Chloroquine-Associated H+ Leak from the Malaria Parasite's Digestive Vacuole

Antimicrobial Agents and Chemotherapy, 2008-12, Vol.52 (12), p.4374-4380

2008

Volltextzugriff (PDF)

Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite’s chloroquine resistance transporter

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (17), p.E1759-E1767

2014

Volltextzugriff (PDF)

Ion Regulation in the Malaria Parasite

Annual review of microbiology, 2015-01, Vol.69 (1), p.341-359

Kirk, Kiaran

2015

Volltextzugriff (PDF)

Metabolite profiling of the intraerythrocytic malaria parasite Plasmodium falciparum by 1H NMR spectroscopy

NMR in biomedicine, 2009-04, Vol.22 (3), p.292-302

2009

Volltextzugriff (PDF)

The Membrane Potential of the Intraerythrocytic Malaria Parasite Plasmodium falciparum

The Journal of biological chemistry, 2004-03, Vol.279 (12), p.11264-11272

2004

Volltextzugriff (PDF)

Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance

Molecular microbiology, 2005-04, Vol.56 (2), p.323-333

2005

Volltextzugriff (PDF)

verapamil-sensitive chloroquine-associated H⁺ leak from the digestive vacuole in chloroquine-resistant malaria parasites

Journal of cell science, 2008-05, Vol.121 (10), p.1624-1632

2008

Volltextzugriff (PDF)

Targeting nutrient uptake mechanisms in Plasmodium

Current drug targets, 2007-01, Vol.8 (1), p.75

2007

Volltextzugriff (PDF)

Loss of pH control in Plasmodium falciparum parasites subjected to oxidative stress

PloS one, 2013-03, Vol.8 (3), p.e58933

2013

Volltextzugriff (PDF)

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The malaria parasite cation ATPase PfATP4 and its role in the mechanism of action of a new arsenal of antimalarial drugs

Membrane Transport in the Malaria-Infected Erythrocyte

Membrane transport in the malaria parasite and its host erythrocyte

Diverse chemotypes disrupt ion homeostasis in the malaria parasite

Identifying the major lactate transporter of Toxoplasma gondii tachyzoites

Chloroquine Transport via the Malaria Parasite's Chloroquine Resistance Transporter

Na+ Regulation in the Malaria Parasite Plasmodium falciparum Involves the Cation ATPase PfATP4 and Is a Target of the Spiroindolone Antimalarials

Coordinated action of multiple transporters in the acquisition of essential cationic amino acids by the intracellular parasite Toxoplasma gondii

The tyrosine transporter of Toxoplasma gondii is a member of the newly defined apicomplexan amino acid transporter (ApiAT) family

Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites

Substrate-mediated regulation of the arginine transporter of Toxoplasma gondii

A G358S mutation in the Plasmodium falciparum Na + pump PfATP4 confers clinically-relevant resistance to cipargamin

Mice Deficient in the Putative Phospholipid Flippase ATP11C Exhibit Altered Erythrocyte Shape, Anemia, and Reduced Erythrocyte Life Span

Diverse antimalarials from whole-cell phenotypic screens disrupt malaria parasite ion and volume homeostasis

The Malaria Parasite's Lactate Transporter PfFNT Is the Target of Antiplasmodial Compounds Identified in Whole Cell Phenotypic Screens

A female gametocyte-specific ABC transporter plays a role in lipid metabolism in the malaria parasite

Chloroquine Resistance-Conferring Mutations in pfcrt Give Rise to a Chloroquine-Associated H+ Leak from the Malaria Parasite's Digestive Vacuole

Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite’s chloroquine resistance transporter

Ion Regulation in the Malaria Parasite

Metabolite profiling of the intraerythrocytic malaria parasite Plasmodium falciparum by 1H NMR spectroscopy

The Membrane Potential of the Intraerythrocytic Malaria Parasite Plasmodium falciparum

Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance

verapamil-sensitive chloroquine-associated H⁺ leak from the digestive vacuole in chloroquine-resistant malaria parasites

Targeting nutrient uptake mechanisms in Plasmodium

Loss of pH control in Plasmodium falciparum parasites subjected to oxidative stress

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