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Usefulness of Two-Compartment Model-Assisted and Static Overall Inhibitory-Activity Method for Prediction of Drug–Drug Interaction

Biological and Pharmaceutical Bulletin, 2017/12/01, Vol.40(12), pp.2024-2037

2017

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Pharmacokinetic/Pharmacodynamic Models of an Alzheimer's Drug, Donepezil, in Rats

Drug metabolism and disposition, 2023-03, Vol.51 (3), p.329-337

2023

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An approach using a gamma-distributed delay model to evaluate the anticancer effect of doxorubicin-encapsulated polymeric micelles by predictive pharmacokinetic-pharmacodynamic modeling

Drug metabolism and pharmacokinetics, 2024-04, Vol.55, p.100961, Article 100961

2024

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Simulations of Cytochrome P450 3A4-Mediated Drug-Drug Interactions by Simple Two-Compartment Model-Assisted Static Method

Journal of pharmaceutical sciences, 2017-05, Vol.106 (5), p.1426-1438

2017

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Delivery of Oxytocin to the Brain for the Treatment of Autism Spectrum Disorder by Nasal Application

Molecular pharmaceutics, 2018-03, Vol.15 (3), p.1105-1111

2018

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A synthetic porphyrin as an effective dual antidote against carbon monoxide and cyanide poisoning

Proceedings of the National Academy of Sciences - PNAS, 2023-02, Vol.120 (9), p.e2209924120-e2209924120

2023

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Exploring the multiple effects of nifedipine and captopril administration in spontaneously hypertensive rats through pharmacokinetic‐pharmacodynamic analyses

Pharmacology research & perspectives, 2024-08, Vol.12 (4), p.e1249-n/a

2024

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Transnasal Delivery of the Peptide Agonist Specific to Neuromedin‑U Receptor 2 to the Brain for the Treatment of Obesity

Molecular pharmaceutics, 2020-01, Vol.17 (1), p.32-39

2020

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Novel Strategy for the Systemic Delivery of Furosemide Based on a New Drug Transport Mechanism

Biological and Pharmaceutical Bulletin, 2018/12/01, Vol.41(12), pp.1769-1777

2018

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The relationship between in vivo nasal drug clearance and in vitro nasal mucociliary clearance: Application to the prediction of nasal drug absorption

European journal of pharmaceutical sciences, 2018-05, Vol.117, p.21-26

2018

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Rapid Access to Dispirocyclic Scaffolds Enabled by Diastereoselective Intramolecular Double Functionalization of Benzene Rings

Chemistry, an Asian journal, 2020-12, Vol.15 (24), p.4271-4274

2020

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Interplay of UDP-Glucuronosyltransferase and CYP2C8 for CYP2C8 Mediated Drug Oxidation and Its Impact on Drug-Drug Interaction Produced by Standardized CYP2C8 Inhibitors, Clopidogrel

Clinical pharmacokinetics, 2024-01, Vol.63 (1), p.43-56

2024

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Interplay of UDP-Glucuronosyltransferase and CYP2C8 for CYP2C8 Mediated Drug Oxidation and Its Impact on Drug–Drug Interaction Produced by Standardized CYP2C8 Inhibitors, Clopidogrel and Gemfibrozil

Clinical pharmacokinetics, 2024, Vol.63 (1), p.43-56

2024

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Quantitative Estimation of the Effect of Nasal Mucociliary Function on in Vivo Absorption of Norfloxacin after Intranasal Administration to Rats

Molecular pharmaceutics, 2018-10, Vol.15 (10), p.4462-4469

2018

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α2-Antiplasmin as a potential regulator of the spatial memory process and age-related cognitive decline

Molecular brain, 2020-10, Vol.13 (1), p.1-14, Article 140

2020

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Pharmacokinetics/Pharmacodynamic Analysis to Link Pharmacokinetics to Efficacy and Drug Interaction of Alzheimer's Disease Drugs

YAKUGAKU ZASSHI, 2021/06/01, Vol.141(6), pp.831-833

Kiriyama, Akiko

2021

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Novel Strategy for the Systemic Delivery of Furosemide Based on a New Drug Transport Mechanism

Biological and Pharmaceutical Bulletin, 2018-12, Vol.41 (12), p.1769-1777

2018

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Tumoral Pharmacokinetic-Pharmacodynamic Simulation of Doxorubicin-Encapsulated Polymeric Micelles Using a Tissue-Isolated Tumor Perfusion System

Molecular pharmaceutics, 2024-10

2024

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Variations in the inner core affect the pharmacokinetics of indomethacin-encapsulated polymeric micelles

International journal of pharmaceutics, 2024-04, Vol.654, p.123933-123933, Article 123933

2024

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Left-Right Difference in Brain Pharmacokinetics Following Nasal Administration Via One-Site Nostrils

Journal of pharmaceutical sciences, 2024-08, Vol.113 (8), p.2633-2640

2024

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Pharmacokinetic–Pharmacodynamic Analysis of pH-Responsive Doxorubicin-Releasing Micelles with Anticancer Activity

Molecular pharmaceutics, 2024-07, Vol.21 (7), p.3173-3185

2024

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Cis-Selective Double Spirocyclization via Dearomatization and Isomerization under Thermodynamic Control

Journal of organic chemistry, 2023-02, Vol.88 (3), p.1803-1814

2023

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Evaluation of anticancer effect of micelle-encapsulated doxorubicin using gamma-distributed delay model

Journal of drug delivery science and technology, 2024-01, Vol.91, p.105244, Article 105244

2024

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Supramolecular Complexation in Biological Media: NMR Study on Inclusion of an Anionic Tetraarylporphyrin into a Per‐O‐Methylated β‐Cyclodextrin Cavity in Serum, Blood, and Urine

Chemistry, an Asian journal, 2019-10, Vol.14 (19), p.3320-3328

2019

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Pharmacokinetic-pharmacodynamic analyses of antihypertensive drugs, nifedipine and propranolol, in spontaneously hypertensive rats to investigate characteristics of effect and side effects

Regulatory toxicology and pharmacology, 2016-04, Vol.76, p.21-29

2016

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Usefulness of Two-Compartment Model-Assisted and Static Overall Inhibitory-Activity Method for Prediction of Drug–Drug Interaction

Pharmacokinetic/Pharmacodynamic Models of an Alzheimer's Drug, Donepezil, in Rats

An approach using a gamma-distributed delay model to evaluate the anticancer effect of doxorubicin-encapsulated polymeric micelles by predictive pharmacokinetic-pharmacodynamic modeling

Simulations of Cytochrome P450 3A4-Mediated Drug-Drug Interactions by Simple Two-Compartment Model-Assisted Static Method

Delivery of Oxytocin to the Brain for the Treatment of Autism Spectrum Disorder by Nasal Application

A synthetic porphyrin as an effective dual antidote against carbon monoxide and cyanide poisoning

Exploring the multiple effects of nifedipine and captopril administration in spontaneously hypertensive rats through pharmacokinetic‐pharmacodynamic analyses

Transnasal Delivery of the Peptide Agonist Specific to Neuromedin‑U Receptor 2 to the Brain for the Treatment of Obesity

Novel Strategy for the Systemic Delivery of Furosemide Based on a New Drug Transport Mechanism

The relationship between in vivo nasal drug clearance and in vitro nasal mucociliary clearance: Application to the prediction of nasal drug absorption

Rapid Access to Dispirocyclic Scaffolds Enabled by Diastereoselective Intramolecular Double Functionalization of Benzene Rings

Interplay of UDP-Glucuronosyltransferase and CYP2C8 for CYP2C8 Mediated Drug Oxidation and Its Impact on Drug-Drug Interaction Produced by Standardized CYP2C8 Inhibitors, Clopidogrel

Interplay of UDP-Glucuronosyltransferase and CYP2C8 for CYP2C8 Mediated Drug Oxidation and Its Impact on Drug–Drug Interaction Produced by Standardized CYP2C8 Inhibitors, Clopidogrel and Gemfibrozil

Quantitative Estimation of the Effect of Nasal Mucociliary Function on in Vivo Absorption of Norfloxacin after Intranasal Administration to Rats

α2-Antiplasmin as a potential regulator of the spatial memory process and age-related cognitive decline

Pharmacokinetics/Pharmacodynamic Analysis to Link Pharmacokinetics to Efficacy and Drug Interaction of Alzheimer's Disease Drugs

Novel Strategy for the Systemic Delivery of Furosemide Based on a New Drug Transport Mechanism

Tumoral Pharmacokinetic-Pharmacodynamic Simulation of Doxorubicin-Encapsulated Polymeric Micelles Using a Tissue-Isolated Tumor Perfusion System

Variations in the inner core affect the pharmacokinetics of indomethacin-encapsulated polymeric micelles

Left-Right Difference in Brain Pharmacokinetics Following Nasal Administration Via One-Site Nostrils

Pharmacokinetic–Pharmacodynamic Analysis of pH-Responsive Doxorubicin-Releasing Micelles with Anticancer Activity

Cis-Selective Double Spirocyclization via Dearomatization and Isomerization under Thermodynamic Control

Evaluation of anticancer effect of micelle-encapsulated doxorubicin using gamma-distributed delay model

Supramolecular Complexation in Biological Media: NMR Study on Inclusion of an Anionic Tetraarylporphyrin into a Per‐O‐Methylated β‐Cyclodextrin Cavity in Serum, Blood, and Urine

Pharmacokinetic-pharmacodynamic analyses of antihypertensive drugs, nifedipine and propranolol, in spontaneously hypertensive rats to investigate characteristics of effect and side effects

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