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Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

Cell metabolism, 2013-01, Vol.17 (1), p.141-152

2013

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Accidental spills at sea – Risk, impact, mitigation and the need for co-ordinated post-incident monitoring

Marine pollution bulletin, 2010-06, Vol.60 (6), p.797-803

2010

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Discovery and Preclinical Profile of Saxagliptin (BMS-477118): A Highly Potent, Long-Acting, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

Journal of medicinal chemistry, 2005-07, Vol.48 (15), p.5025-5037

2005

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Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition

Clinical science (1979), 2010-01, Vol.118 (1), p.31-41

2010

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Qualification of oil-spill treatment products – Adopting the Baffled Flask Test for testing of dispersant efficacy in the UK

Marine pollution bulletin, 2018-04, Vol.129 (2), p.609-614

2018

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The use of chemical dispersants to combat oil spills at sea: A review of practice and research needs in Europe

Marine pollution bulletin, 2007-07, Vol.54 (7), p.827-838

2007

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A standardised approach to the environmental risk assessment of potentially polluting wrecks

Marine pollution bulletin, 2019-05, Vol.142, p.290-302

2019

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The principles of effective post-spill environmental monitoring in marine environments and their application to preparedness assessment

Marine pollution bulletin, 2014-05, Vol.82 (1-2), p.11-18

2014

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Foveal Anatomic Associations with the Secondary Peak and the Slope of the Macular Pigment Spatial Profile

Investigative ophthalmology & visual science, 2009-03, Vol.50 (3), p.1383-1391

2009

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Involvement of DPP‐IV catalytic residues in enzyme–saxagliptin complex formation

Protein science, 2008-02, Vol.17 (2), p.240-250

2008

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A circulating microRNA signature as noninvasive diagnostic and prognostic biomarkers for nonalcoholic steatohepatitis

BMC genomics, 2018-03, Vol.19 (1), p.188-188, Article 188

2018

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A central dip in the macular pigment spatial profile is associated with age and smoking

Investigative ophthalmology & visual science, 2010-12, Vol.51 (12), p.6722-6728

2010

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Potency, selectivity and prolonged binding of saxagliptin to DPP4: maintenance of DPP4 inhibition by saxagliptin in vitro and ex vivo when compared to a rapidly-dissociating DPP4 inhibitor

BMC pharmacology, 2012-04, Vol.12 (1), p.2-2, Article 2

2012

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Synthesis and SAR of azolopyrimidines as potent and selective dipeptidyl peptidase-4 (DPP4) inhibitors for type 2 diabetes

Bioorganic & medicinal chemistry letters, 2010-08, Vol.20 (15), p.4395-4398

2010

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Pharmacokinetics of the dipeptidyl peptidase 4 inhibitor saxagliptin in rats, dogs, and monkeys and clinical projections

Drug metabolism and disposition, 2009-06, Vol.37 (6), p.1164-1171

2009

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Substitution of hazardous offshore chemicals in UK waters: an evaluation of their use and discharge from 2000 to 2012

Journal of cleaner production, 2015-01, Vol.87, p.675-682

2015

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Substituted piperidinyl glycinyl 2-cyano-4,5-methano pyrrolidines as potent and stable dipeptidyl peptidase IV inhibitors

Bioorganic & medicinal chemistry letters, 2013-03, Vol.23 (6), p.1622-1625

2013

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Towards a scheme of toxic equivalency factors (TEFs) for the acute toxicity of PAHs in sediment

Ecotoxicology and environmental safety, 2011-11, Vol.74 (8), p.2245-2251

2011

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Changes in macular pigment optical density and serum concentrations of lutein and zeaxanthin in response to weight loss

British journal of nutrition, 2011-04, Vol.105 (7), p.1036-1046

2011

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Polycyclic aromatic hydrocarbons in fish from St Helena, South Atlantic, in relation to an historic wreck

Marine pollution bulletin, 2014-12, Vol.89 (1-2), p.451-454

2014

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Optimization of Activity, Selectivity, and Liability Profiles in 5‑Oxopyrrolopyridine DPP4 Inhibitors Leading to Clinical Candidate (Sa)‑2-(3-(Aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo‑5H‑pyrrolo[3,4‑b]pyridin-6(7H)‑yl)‑N,N‑dimethylacetamide (BMS-767778)

Journal of medicinal chemistry, 2013-09, Vol.56 (18), p.7343-7357

2013

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Interlaboratory Proficiency Testing for Measurement of the Polycyclic Aromatic Hydrocarbon Metabolite 1-Hydroxypyrene in Fish Bile for Marine Environmental Monitoring

Journal of AOAC International, 2013-05, Vol.96 (3), p.635-641

2013

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Oil spill treatment products approval: The UK approach and potential application to the Gulf region

Marine pollution bulletin, 2008-07, Vol.56 (7), p.1243-1247

2008

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Relationship between sex steroid and vitellogenin concentrations in flounder (Platichthys flesus) sampled from an estuary contaminated with estrogenic endocrine-disrupting compounds

Environmental health perspectives, 2006-04, Vol.114 Suppl 1 (Suppl 1), p.27-31

2006

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DPP8 and DPP9 expression in cynomolgus monkey and Sprague Dawley rat tissues

Regulatory peptides, 2013-09, Vol.186, p.26-35

2013

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Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

Accidental spills at sea – Risk, impact, mitigation and the need for co-ordinated post-incident monitoring

Discovery and Preclinical Profile of Saxagliptin (BMS-477118): A Highly Potent, Long-Acting, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition

Qualification of oil-spill treatment products – Adopting the Baffled Flask Test for testing of dispersant efficacy in the UK

The use of chemical dispersants to combat oil spills at sea: A review of practice and research needs in Europe

A standardised approach to the environmental risk assessment of potentially polluting wrecks

The principles of effective post-spill environmental monitoring in marine environments and their application to preparedness assessment

Foveal Anatomic Associations with the Secondary Peak and the Slope of the Macular Pigment Spatial Profile

Involvement of DPP‐IV catalytic residues in enzyme–saxagliptin complex formation

A circulating microRNA signature as noninvasive diagnostic and prognostic biomarkers for nonalcoholic steatohepatitis

A central dip in the macular pigment spatial profile is associated with age and smoking

Potency, selectivity and prolonged binding of saxagliptin to DPP4: maintenance of DPP4 inhibition by saxagliptin in vitro and ex vivo when compared to a rapidly-dissociating DPP4 inhibitor

Synthesis and SAR of azolopyrimidines as potent and selective dipeptidyl peptidase-4 (DPP4) inhibitors for type 2 diabetes

Pharmacokinetics of the dipeptidyl peptidase 4 inhibitor saxagliptin in rats, dogs, and monkeys and clinical projections

Substitution of hazardous offshore chemicals in UK waters: an evaluation of their use and discharge from 2000 to 2012

Substituted piperidinyl glycinyl 2-cyano-4,5-methano pyrrolidines as potent and stable dipeptidyl peptidase IV inhibitors

Towards a scheme of toxic equivalency factors (TEFs) for the acute toxicity of PAHs in sediment

Changes in macular pigment optical density and serum concentrations of lutein and zeaxanthin in response to weight loss

Polycyclic aromatic hydrocarbons in fish from St Helena, South Atlantic, in relation to an historic wreck

Optimization of Activity, Selectivity, and Liability Profiles in 5‑Oxopyrrolopyridine DPP4 Inhibitors Leading to Clinical Candidate (Sa)‑2-(3-(Aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo‑5H‑pyrrolo[3,4‑b]pyridin-6(7H)‑yl)‑N,N‑dimethylacetamide (BMS-767778)

Interlaboratory Proficiency Testing for Measurement of the Polycyclic Aromatic Hydrocarbon Metabolite 1-Hydroxypyrene in Fish Bile for Marine Environmental Monitoring

Oil spill treatment products approval: The UK approach and potential application to the Gulf region

Relationship between sex steroid and vitellogenin concentrations in flounder (Platichthys flesus) sampled from an estuary contaminated with estrogenic endocrine-disrupting compounds

DPP8 and DPP9 expression in cynomolgus monkey and Sprague Dawley rat tissues

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