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A Brief History of Use of Animals in Biomedical Research and Perspective on Non-Animal Alternatives

ILAR journal, 2021-12, Vol.62 (1-2), p.7-16

2021

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Perspectives on using a multiplex human kidney safety biomarker panel to detect cisplatin-induced tubular toxicity in male and female Cynomolgus monkeys

Toxicology and applied pharmacology, 2017-12, Vol.336, p.66-74

2017

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Evaluation and applications of radiotelemetry in small laboratory animals

Physiological genomics, 2003-05, Vol.13 (3), p.197-205

2003

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The harm in harm benefit analysis terminology and safety pharmacology

Journal of pharmacological and toxicological methods, 2019-09, Vol.99, p.106595, Article 106595

2019

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External passive heat-generating devises and body temperature support in small animals

Journal of pharmacological and toxicological methods, 2019-09, Vol.99, p.106595, Article 106595

2019

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History of the National Academies of Sciences, Engineering, and Medicine's Institute for Laboratory Animal Research

ILAR journal, 2021-12, Vol.62 (3), p.278-294

2021

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Pharmaceutical toxicology: Designing studies to reduce animal use, while maximizing human translation

Regulatory toxicology and pharmacology, 2013-06, Vol.66 (1), p.88-103

2013

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A Standard of Knowledge for the Professional Practice of Toxicology

Environmental health perspectives, 2015-08, Vol.123 (8), p.743-743

2015

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Scientific Knowledge and Technology, Animal Experimentation, and Pharmaceutical Development

ILAR journal, 2016-12, Vol.57 (2), p.101-108

2016

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Fit for Purpose Assessment: A New Direction for IACUCs

ILAR journal, 2021-12, Vol.62 (3), p.314-331

2021

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A Historical View and Vision into the Future of the Field of Safety Pharmacology

Handbook of experimental pharmacology, 2015, Vol.229, p.3

2015

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Uptake of propranolol, a cardiovascular pharmaceutical, from water into fish plasma and its effects on growth and organ biometry

Aquatic toxicology, 2009-07, Vol.93 (4), p.217-224

2009

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A defense of 'risk-benefit' terminology

Lab animal, 2015-10, Vol.44 (10), p.403-407

2015

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Using data from drug discovery and development to aid the aquatic environmental risk assessment of human pharmaceuticals: Concepts, considerations, and challenges

Integrated environmental assessment and management, 2010-01, Vol.6 (1), p.38-51

2010

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In vivo and in vitro liver and gill EROD activity in rainbow trout (Oncorhynchus mykiss) exposed to the beta-blocker propranolol

Environmental toxicology, 2012-10, Vol.27 (10), p.573-582

2012

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A peripherally restricted P2Y12 receptor antagonist altered rat tumor incidences with no human relevance: Mode of action consistent with dopamine agonism

Toxicology reports, 2014-11, Vol.1 (C), p.1202-1212

2014

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Renal biomarker changes associated with hyaline droplet nephropathy in rats are time and potentially compound dependent

Toxicology (Amsterdam), 2013-01, Vol.303, p.133-138

2013

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The value of repeating studies and multiple controls: replicated 28-day growth studies of rainbow trout exposed to clofibric acid

Environmental toxicology and chemistry, 2010-12, Vol.29 (12), p.2831-2839

2010

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Safety pharmacology in 2010 and beyond: survey of significant events of the past 10 years and a roadmap to the immediate-, intermediate- and long-term future in recognition of the tenth anniversary of the Safety Pharmacology Society

Journal of pharmacological and toxicological methods, 2011-07, Vol.64 (1), p.7-15

2011

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Inhibition of Oestradiol-induced Prolactin Release in a Dual-Cannulated Ovariectomized Rat Model by Carmoxirole, a Peripherally Restricted Dopamine Agonist

Basic & clinical pharmacology & toxicology, 2012-12, Vol.111 (6), p.411-416

2012

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Drugs effects on ventricular repolarization: A critical evaluation of the strengths and weaknesses of current methodologies and regulatory practices

Journal of pharmacological and toxicological methods, 2005-07, Vol.52 (1), p.12-21

2005

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Safety pharmacology and risk assessment

Fundamental & clinical pharmacology, 2002-06, Vol.16 (3), p.175-182

2002

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A peripherally restricted P2Y 12 receptor antagonist altered rat tumor incidences with no human relevance: Mode of action consistent with dopamine agonism

Toxicology reports, 2014, Vol.1, p.1202-1212

2014

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Conference Report: DIA/PhRMA workshop on DBS Sampling in the Pharmaceutical Industry: Methodology, Implementation & Best Practices

Bioanalysis, 2010-08, Vol.2 (8), p.1355-1359

2010

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Polymeric Gadolinium Chelate Magnetic Resonance Imaging Contrast Agents: Design, Synthesis, and Properties

Bioconjugate chemistry, 1999-05, Vol.10 (3), p.361-370

1999

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A Brief History of Use of Animals in Biomedical Research and Perspective on Non-Animal Alternatives

Perspectives on using a multiplex human kidney safety biomarker panel to detect cisplatin-induced tubular toxicity in male and female Cynomolgus monkeys

Evaluation and applications of radiotelemetry in small laboratory animals

The harm in harm benefit analysis terminology and safety pharmacology

External passive heat-generating devises and body temperature support in small animals

History of the National Academies of Sciences, Engineering, and Medicine's Institute for Laboratory Animal Research

Pharmaceutical toxicology: Designing studies to reduce animal use, while maximizing human translation

A Standard of Knowledge for the Professional Practice of Toxicology

Scientific Knowledge and Technology, Animal Experimentation, and Pharmaceutical Development

Fit for Purpose Assessment: A New Direction for IACUCs

A Historical View and Vision into the Future of the Field of Safety Pharmacology

Uptake of propranolol, a cardiovascular pharmaceutical, from water into fish plasma and its effects on growth and organ biometry

A defense of 'risk-benefit' terminology

Using data from drug discovery and development to aid the aquatic environmental risk assessment of human pharmaceuticals: Concepts, considerations, and challenges

In vivo and in vitro liver and gill EROD activity in rainbow trout (Oncorhynchus mykiss) exposed to the beta-blocker propranolol

A peripherally restricted P2Y12 receptor antagonist altered rat tumor incidences with no human relevance: Mode of action consistent with dopamine agonism

Renal biomarker changes associated with hyaline droplet nephropathy in rats are time and potentially compound dependent

The value of repeating studies and multiple controls: replicated 28-day growth studies of rainbow trout exposed to clofibric acid

Safety pharmacology in 2010 and beyond: survey of significant events of the past 10 years and a roadmap to the immediate-, intermediate- and long-term future in recognition of the tenth anniversary of the Safety Pharmacology Society

Inhibition of Oestradiol-induced Prolactin Release in a Dual-Cannulated Ovariectomized Rat Model by Carmoxirole, a Peripherally Restricted Dopamine Agonist

Drugs effects on ventricular repolarization: A critical evaluation of the strengths and weaknesses of current methodologies and regulatory practices

Safety pharmacology and risk assessment

A peripherally restricted P2Y 12 receptor antagonist altered rat tumor incidences with no human relevance: Mode of action consistent with dopamine agonism

Conference Report: DIA/PhRMA workshop on DBS Sampling in the Pharmaceutical Industry: Methodology, Implementation & Best Practices

Polymeric Gadolinium Chelate Magnetic Resonance Imaging Contrast Agents: Design, Synthesis, and Properties

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