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Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C

Nature (London), 2014-10, Vol.514 (7524), p.646-649

2014

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A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response

Nature cell biology, 2012-03, Vol.14 (3), p.318

2012

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Substrate degradation by the proteasome: A single-molecule kinetic analysis

Science (American Association for the Advancement of Science), 2015-04, Vol.348 (6231), p.200-200

2015

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The Insulin Receptor Adaptor IRS2 is an APC/C Substrate That Promotes Cell Cycle Protein Expression and a Robust Spindle Assembly Checkpoint

Molecular & cellular proteomics, 2020-09, Vol.19 (9), p.1450-1467

2020

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Enhancement of proteasome activity by a small-molecule inhibitor of USP14

Nature (London), 2010-09, Vol.467 (7312), p.179-184

2010

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Trimming of Ubiquitin Chains by Proteasome-associated Deubiquitinating Enzymes

Molecular & cellular proteomics, 2011-05, Vol.10 (5), p.R110.003871, Article R110.003871

2011

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USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites

Nature (London), 2016-04, Vol.532 (7599), p.398-401

2016

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Pharmacologic Inhibition of the Anaphase-Promoting Complex Induces A Spindle Checkpoint-Dependent Mitotic Arrest in the Absence of Spindle Damage

Cancer cell, 2010-10, Vol.18 (4), p.382-395

2010

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When 2 + 2 = 5: The origins and fates of aneuploid and tetraploid cells

Biochimica et biophysica acta, 2008-09, Vol.1786 (1), p.4-14

King, Randall W.

2008

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Understanding cytokinesis failure

Advances in experimental medicine and biology, 2010, Vol.676, p.27

2010

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Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines

Nature, 2005-10, Vol.437 (4061), p.1038-1042

2005

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A Step-By-Step Guide to Case-Based Collaborative Learning (CBCL)

1, 2022

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Identification of Deubiquitinase Substrates in Xenopus Egg Extract

Methods in molecular biology (Clifton, N.J.), 2023, Vol.2591, p.219

2023

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An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination

Nature chemical biology, 2012-02, Vol.8 (4), p.383

2012

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Vigilance and Validation: Keys to Success in RNAi Screening

ACS chemical biology, 2011-01, Vol.6 (1), p.47-60

2011

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Specificity profiling of deubiquitylases against endogenously generated ubiquitin-protein conjugates

Cell chemical biology, 2024-07, Vol.31 (7), p.1349-1362.e5

2024

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A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens

Nature methods, 2012-04, Vol.9 (4), p.363

2012

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A Nonapoptotic Cell Death Process, Entosis, that Occurs by Cell-in-Cell Invasion

Cell, 2007-11, Vol.131 (5), p.966-979

2007

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Using cognitive load theory to evaluate and improve preparatory materials and study time for the flipped classroom

BMC medical education, 2023-05, Vol.23 (1), p.345-345, Article 345

2023

Volltextzugriff (PDF)

An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons

The Journal of biological chemistry, 2017-11, Vol.292 (47), p.19209-19225

2017

Volltextzugriff (PDF)

Proteomics of broad deubiquitylase inhibition unmasks redundant enzyme function to reveal substrates and assess enzyme specificity

Cell chemical biology, 2021-04, Vol.28 (4), p.487-502.e5

2021

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A non-genetic route to aneuploidy in human cancers

Nature cell biology, 2011-03, Vol.13 (3), p.324

2011

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Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

Nature cell biology, 2006-07, Vol.8 (7), p.700-710

2006

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APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

Nature cell biology, 2012-02, Vol.14 (2), p.168

2012

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Deubiquitinating Enzyme Ubp6 Functions Noncatalytically to Delay Proteasomal Degradation

Cell, 2006-10, Vol.127 (1), p.99-111

2006

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Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C

A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response

Substrate degradation by the proteasome: A single-molecule kinetic analysis

The Insulin Receptor Adaptor IRS2 is an APC/C Substrate That Promotes Cell Cycle Protein Expression and a Robust Spindle Assembly Checkpoint

Enhancement of proteasome activity by a small-molecule inhibitor of USP14

Trimming of Ubiquitin Chains by Proteasome-associated Deubiquitinating Enzymes

USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites

Pharmacologic Inhibition of the Anaphase-Promoting Complex Induces A Spindle Checkpoint-Dependent Mitotic Arrest in the Absence of Spindle Damage

When 2 + 2 = 5: The origins and fates of aneuploid and tetraploid cells

Understanding cytokinesis failure

Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines

A Step-By-Step Guide to Case-Based Collaborative Learning (CBCL)

Identification of Deubiquitinase Substrates in Xenopus Egg Extract

An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination

Vigilance and Validation: Keys to Success in RNAi Screening

Specificity profiling of deubiquitylases against endogenously generated ubiquitin-protein conjugates

A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens

A Nonapoptotic Cell Death Process, Entosis, that Occurs by Cell-in-Cell Invasion

Using cognitive load theory to evaluate and improve preparatory materials and study time for the flipped classroom

An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons

Proteomics of broad deubiquitylase inhibition unmasks redundant enzyme function to reveal substrates and assess enzyme specificity

A non-genetic route to aneuploidy in human cancers

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

Deubiquitinating Enzyme Ubp6 Functions Noncatalytically to Delay Proteasomal Degradation

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