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Non-traditional roles of complement in type 2 diabetes: Metabolism, insulin secretion and homeostasis

Molecular immunology, 2017-04, Vol.84, p.34-42

2017

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The Complement Inhibitor CD59 Regulates Insulin Secretion by Modulating Exocytotic Events

Cell metabolism, 2014-05, Vol.19 (5), p.883-890

2014

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Complement Component 3 Is Required for Tissue Damage, Neutrophil Infiltration, and Ensuring NET Formation in Acute Pancreatitis

European surgical research, 2020, Vol.61 (6), p.163-176

2020

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C4b-binding protein inhibits particulate- and crystalline-induced NLRP3 inflammasome activation

Frontiers in immunology, 2023, Vol.14, p.1149822-1149822

2023

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The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation

Diabetologia, 2017-08, Vol.60 (8), p.1522-1533

2017

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Functional analyses of complement convertases using C3 and C5-depleted sera

PloS one, 2012-10, Vol.7 (10), p.e47245-e47245

2012

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Intracellular complement: Evidence, definitions, controversies, and solutions

Immunological reviews, 2023-01, Vol.313 (1), p.104-119

2023

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Outside in: Roles of complement in autophagy

British journal of pharmacology, 2021-07, Vol.178 (14), p.2786-2801

2021

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Coherent power scaling in photonic crystal surface emitting laser arrays

AIP advances, 2021-01, Vol.11 (1), p.015017-015017-4

2021

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Intracellular cytosolic complement component C3 regulates cytoprotective autophagy in pancreatic beta cells by interaction with ATG16L1

Autophagy, 2019-05, Vol.15 (5), p.919-921

2019

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Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation

Cell metabolism, 2019-01, Vol.29 (1), p.202-210.e6

2019

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Intracellular C3 protects β-cells from IL-1β-driven cytotoxicity via interaction with Fyn-related kinase

Proceedings of the National Academy of Sciences - PNAS, 2024-02, Vol.121 (8), p.e2312621121

2024

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The Noncoding RNA nc886 Regulates PKR Signaling and Cytokine Production in Human Cells

The Journal of immunology (1950), 2019-01, Vol.202 (1), p.131-141

2019

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Alternative translation and retrotranslocation of cytosolic C3 that detects cytoinvasive bacteria

Cellular and molecular life sciences : CMLS, 2022-06, Vol.79 (6), p.291-291, Article 291

2022

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A cryptic non–GPI‐anchored cytosolic isoform of CD59 controls insulin exocytosis in pancreatic β‐cells by interaction with SNARE proteins

The FASEB journal, 2019-11, Vol.33 (11), p.12425-12434

2019

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CD46 Activation Regulates miR-150-Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+ T Cells

The Journal of immunology (1950), 2016-02, Vol.196 (4), p.1636-1645

2016

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Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets

Proceedings of the National Academy of Sciences - PNAS, 2022-06, Vol.119 (24), p.e2120083119-e2120083119

2022

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1.5 μm Epitaxially Regrown Photonic Crystal Surface Emitting Laser Diode

IEEE photonics technology letters, 2020-12, Vol.32 (24), p.1531-1534

2020

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FACIN, a Double-Edged Sword of the Emerging Periodontal Pathogen Filifactor alocis: A Metabolic Enzyme Moonlighting as a Complement Inhibitor

The Journal of immunology (1950), 2016-10, Vol.197 (8), p.3245-3259

2016

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C4b-binding Protein Protects β-Cells from Islet Amyloid Polypeptide-induced Cytotoxicity

The Journal of biological chemistry, 2016-10, Vol.291 (41), p.21644-21655

2016

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Truncated and full-length thioredoxin-1 have opposing activating and inhibitory properties for human complement with relevance to endothelial surfaces

The Journal of immunology (1950), 2012-04, Vol.188 (8), p.4103-4112

2012

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The human complement inhibitor Sushi Domain-Containing Protein 4 (SUSD4) expression in tumor cells and infiltrating T cells is associated with better prognosis of breast cancer patients

BMC cancer, 2015-10, Vol.15 (1), p.737-737, Article 737

2015

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Unraveling the role of Sushi-domain containing protein 4 (SUSD4) in pancreatic islets by means of a SUSD4 knockout mouse model

Immunobiology (1979), 2016-10, Vol.221 (10), p.1165-1166

2016

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The complement regulator C4b-binding protein inhibits islet amyloid polypeptide-induced inflammasome activation

Immunobiology (1979), 2016-10, Vol.221 (10), p.1161-1161

2016

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A cryptic non-GPI anchored form of CD59 facilitates insulin secretion from pancreatic beta cells

Immunobiology (1979), 2016-10, Vol.221 (10), p.1165-1165

2016

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Non-traditional roles of complement in type 2 diabetes: Metabolism, insulin secretion and homeostasis

The Complement Inhibitor CD59 Regulates Insulin Secretion by Modulating Exocytotic Events

Complement Component 3 Is Required for Tissue Damage, Neutrophil Infiltration, and Ensuring NET Formation in Acute Pancreatitis

C4b-binding protein inhibits particulate- and crystalline-induced NLRP3 inflammasome activation

The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation

Functional analyses of complement convertases using C3 and C5-depleted sera

Intracellular complement: Evidence, definitions, controversies, and solutions

Outside in: Roles of complement in autophagy

Coherent power scaling in photonic crystal surface emitting laser arrays

Intracellular cytosolic complement component C3 regulates cytoprotective autophagy in pancreatic beta cells by interaction with ATG16L1

Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation

Intracellular C3 protects β-cells from IL-1β-driven cytotoxicity via interaction with Fyn-related kinase

The Noncoding RNA nc886 Regulates PKR Signaling and Cytokine Production in Human Cells

Alternative translation and retrotranslocation of cytosolic C3 that detects cytoinvasive bacteria

A cryptic non–GPI‐anchored cytosolic isoform of CD59 controls insulin exocytosis in pancreatic β‐cells by interaction with SNARE proteins

CD46 Activation Regulates miR-150-Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+ T Cells

Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets

1.5 μm Epitaxially Regrown Photonic Crystal Surface Emitting Laser Diode

FACIN, a Double-Edged Sword of the Emerging Periodontal Pathogen Filifactor alocis: A Metabolic Enzyme Moonlighting as a Complement Inhibitor

C4b-binding Protein Protects β-Cells from Islet Amyloid Polypeptide-induced Cytotoxicity

Truncated and full-length thioredoxin-1 have opposing activating and inhibitory properties for human complement with relevance to endothelial surfaces

The human complement inhibitor Sushi Domain-Containing Protein 4 (SUSD4) expression in tumor cells and infiltrating T cells is associated with better prognosis of breast cancer patients

Unraveling the role of Sushi-domain containing protein 4 (SUSD4) in pancreatic islets by means of a SUSD4 knockout mouse model

The complement regulator C4b-binding protein inhibits islet amyloid polypeptide-induced inflammasome activation

A cryptic non-GPI anchored form of CD59 facilitates insulin secretion from pancreatic beta cells

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