UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 30

Sortiert nach

Single-Stranded siRNAs Activate RNAi in Animals

Cell, 2012-08, Vol.150 (5), p.883-894

2012

Link zum Volltext

Verfügbarkeit prüfen

Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor

Nucleic acids research, 2017-03, Vol.45 (5), p.2294

2017

Link zum Volltext

Verfügbarkeit prüfen

Structural Analysis of Human Argonaute‑2 Bound to a Modified siRNA Guide

Journal of the American Chemical Society, 2016-07, Vol.138 (28), p.8694-8697

2016

Link zum Volltext

Verfügbarkeit prüfen

Comprehensive Structure–Activity Relationship of Triantennary N‑Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes

Journal of medicinal chemistry, 2016-03, Vol.59 (6), p.2718-2733

2016

Link zum Volltext

Verfügbarkeit prüfen

Efficient Synthesis and Biological Evaluation of 5′-GalNAc Conjugated Antisense Oligonucleotides

Bioconjugate chemistry, 2015-08, Vol.26 (8), p.1451-1455

2015

Link zum Volltext

Verfügbarkeit prüfen

Synergistic effect of phosphorothioate, 5′-vinylphosphonate and GalNAc modifications for enhancing activity of synthetic siRNA

Bioorganic & medicinal chemistry letters, 2016-06, Vol.26 (12), p.2817-2820

2016

Link zum Volltext

Verfügbarkeit prüfen

Dose-dependent reduction of somatic expansions but not Htt aggregates by di-valent siRNA-mediated silencing of MSH3 in HdhQ111 mice

Scientific reports, 2024-01, Vol.14 (1), p.2061-2061, Article 2061

2024

Link zum Volltext

Verfügbarkeit prüfen

Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes

Bioorganic & medicinal chemistry letters, 2016-08, Vol.26 (15), p.3690-3693

2016

Link zum Volltext

Verfügbarkeit prüfen

S -Acyl-2-Thioethyl: A Convenient Base-Labile Protecting Group for the Synthesis of siRNAs Containing 5'-Vinylphosphonate

Molecules (Basel, Switzerland), 2019-01, Vol.24 (2), p.225

2019

Link zum Volltext

Verfügbarkeit prüfen

Solid-phase synthesis of 5′-triantennary N-acetylgalactosamine conjugated antisense oligonucleotides using phosphoramidite chemistry

Bioorganic & medicinal chemistry letters, 2015-10, Vol.25 (19), p.4127-4130

2015

Link zum Volltext

Verfügbarkeit prüfen

A convenient synthesis of 5′-triantennary N-acetyl-galactosamine clusters based on nitromethanetrispropionic acid

Bioorganic & medicinal chemistry letters, 2016-05, Vol.26 (9), p.2194-2197

2016

Link zum Volltext

Verfügbarkeit prüfen

Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2'-modifications and enhances antisense activity

Nucleic acids research, 2016-05, Vol.44 (8), p.3892

2016

Link zum Volltext

Verfügbarkeit prüfen

Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primates

Nucleic acids research, 2019-07, Vol.47 (12), p.6045

2019

Link zum Volltext

Verfügbarkeit prüfen

Identification of metabolically stable 5'-phosphate analogs that support single-stranded siRNA activity

Nucleic acids research, 2015-03, Vol.43 (6), p.2993

2015

Link zum Volltext

Verfügbarkeit prüfen

Synthesis and Biophysical Evaluation of 2′,4′-Constrained 2′O-Methoxyethyl and 2′,4′-Constrained 2′O-Ethyl Nucleic Acid Analogues

Journal of organic chemistry, 2010-03, Vol.75 (5), p.1569-1581

2010

Link zum Volltext

Verfügbarkeit prüfen

Evaluation of the effect of 2′-O-methyl, fluoro hexitol, bicyclo and Morpholino nucleic acid modifications on potency of GalNAc conjugated antisense oligonucleotides in mice

Bioorganic & medicinal chemistry letters, 2018-12, Vol.28 (23-24), p.3774-3779

2018

Link zum Volltext

Verfügbarkeit prüfen

Collagen Mimetic Dendrimers

Journal of the American Chemical Society, 2002-12, Vol.124 (51), p.15162-15163

2002

Link zum Volltext

Verfügbarkeit prüfen

The design, synthesis, and characterization of a PAMAM-based triple helical collagen mimetic dendrimer

Tetrahedron, 2006-05, Vol.62 (22), p.5280-5286

2006

Link zum Volltext

Verfügbarkeit prüfen

Peptide Nucleic Acids Conjugated to Short Basic Peptides Show Improved Pharmacokinetics and Antisense Activity in Adipose Tissue

Journal of medicinal chemistry, 2010-05, Vol.53 (10), p.3919-3926

2010

Link zum Volltext

Verfügbarkeit prüfen

Fe(III)-binding collagen mimetics

Inorganic chemistry, 2006-02, Vol.45 (3), p.961-963

2006

Link zum Volltext

Verfügbarkeit prüfen

Evaluation of Basic Amphipathic Peptides for Cellular Delivery of Antisense Peptide Nucleic Acids

Journal of medicinal chemistry, 2006-04, Vol.49 (8), p.2534-2542

2006

Link zum Volltext

Verfügbarkeit prüfen

Structure−Activity Relationship Study on a Simple Cationic Peptide Motif for Cellular Delivery of Antisense Peptide Nucleic Acid

Journal of medicinal chemistry, 2005-10, Vol.48 (21), p.6741-6749

2005

Link zum Volltext

Verfügbarkeit prüfen

FeIII-Binding Collagen Mimetics

Inorganic chemistry, 2006-02, Vol.45 (3), p.961-963

2006

Link zum Volltext

Verfügbarkeit prüfen

Facile and efficient assembly of collagen-like triple helices on a TRIS scaffold

Bioorganic chemistry, 2007-08, Vol.35 (4), p.327-337

2007

Link zum Volltext

Verfügbarkeit prüfen

The new science of protein mimetics

Macromolecular symposia., 2003-10, Vol.201 (1), p.223-236

2003

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 30

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(28)
Mit Volltextzugriff
(26)

Publikationsform

Artikel
(29)
Tagungsberichte
(1)

Sprache

Englisch
(30)
Japanisch
(9)

Erscheinungsjahr

n.n

Thema

Science & Technology
(24)
Life Sciences & Biomedicine
(17)
Animals
(15)
Mice
(15)
Chemistry
(14)
Physical Sciences
(14)
Chemistry, Medicinal
(9)
Chemistry, Organic
(9)
Pharmacology & Pharmacy
(9)
Biochemistry & Molecular Biology
(8)
Structure-Activity Relationship
(8)
Humans
(7)
Male
(7)
Mice, Inbred Balb C
(7)
Organic Chemistry
(7)
Biochemistry
(6)
Oligonucleotides, Antisense - Chemistry
(6)
Acetylgalactosamine - Chemistry
(5)
Biological And Medical Sciences
(5)
Drug Discovery
(5)

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Single-Stranded siRNAs Activate RNAi in Animals

Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor

Structural Analysis of Human Argonaute‑2 Bound to a Modified siRNA Guide

Comprehensive Structure–Activity Relationship of Triantennary N‑Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes

Efficient Synthesis and Biological Evaluation of 5′-GalNAc Conjugated Antisense Oligonucleotides

Synergistic effect of phosphorothioate, 5′-vinylphosphonate and GalNAc modifications for enhancing activity of synthetic siRNA

Dose-dependent reduction of somatic expansions but not Htt aggregates by di-valent siRNA-mediated silencing of MSH3 in HdhQ111 mice

Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes

S -Acyl-2-Thioethyl: A Convenient Base-Labile Protecting Group for the Synthesis of siRNAs Containing 5'-Vinylphosphonate

Solid-phase synthesis of 5′-triantennary N-acetylgalactosamine conjugated antisense oligonucleotides using phosphoramidite chemistry

A convenient synthesis of 5′-triantennary N-acetyl-galactosamine clusters based on nitromethanetrispropionic acid

Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2'-modifications and enhances antisense activity

Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primates

Identification of metabolically stable 5'-phosphate analogs that support single-stranded siRNA activity

Synthesis and Biophysical Evaluation of 2′,4′-Constrained 2′O-Methoxyethyl and 2′,4′-Constrained 2′O-Ethyl Nucleic Acid Analogues

Evaluation of the effect of 2′-O-methyl, fluoro hexitol, bicyclo and Morpholino nucleic acid modifications on potency of GalNAc conjugated antisense oligonucleotides in mice

Collagen Mimetic Dendrimers

The design, synthesis, and characterization of a PAMAM-based triple helical collagen mimetic dendrimer

Peptide Nucleic Acids Conjugated to Short Basic Peptides Show Improved Pharmacokinetics and Antisense Activity in Adipose Tissue

Fe(III)-binding collagen mimetics

Evaluation of Basic Amphipathic Peptides for Cellular Delivery of Antisense Peptide Nucleic Acids

Structure−Activity Relationship Study on a Simple Cationic Peptide Motif for Cellular Delivery of Antisense Peptide Nucleic Acid

FeIII-Binding Collagen Mimetics

Facile and efficient assembly of collagen-like triple helices on a TRIS scaffold

The new science of protein mimetics

Suchergebnisse filtern