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Discoveries and Syntheses of Highly Potent Antimalarial Troponoids

Chemical and Pharmaceutical Bulletin, 2021/06/01, Vol.69(6), pp.564-572

2021

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Comprehensive analysis of biosynthetic gene clusters in bacteria and discovery of Tumebacillus as a potential producer of natural products

Journal of antibiotics, 2023-06, Vol.76 (6), p.316-323

2023

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A new tetronomycin analog, broad‐spectrum and potent antibiotic against drug‐resistant Gram‐positive bacteria

Chemistry & biodiversity, 2024-02, Vol.21 (2), p.e202301834-n/a

2024

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Sesquicillin F, a new insecticidal meroterpenoid produced by Mariannaea macrochlamydospora FKI-4735

Journal of antibiotics, 2021-11, Vol.74 (11), p.817-820

2021

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Pd-catalyzed Regio- and Stereoselective Hydrostannylation of an Alkyl Ethynyl Ether/One-Pot Stille Coupling Enables the Synthesis of 14-Membered Macrolactone of Luminamicin

Organic letters, 2021-03, Vol.23 (5), p.1758-1763

2021

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Total Syntheses and Chemical Biology Studies of Hymeglusin and Fusarilactone A, Novel Circumventors of β‐Lactam Drug Resistance in Methicillin‐Resistant Staphylococcus aureus

ChemMedChem, 2021-07, Vol.16 (13), p.2106-2111

2021

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Traminines A and B, produced by Fusarium concentricum, inhibit oxidative phosphorylation in Saccharomyces cerevisiae mitochondria

Journal of industrial microbiology & biotechnology, 2021-12, Vol.48 (9-10), p.1

2021

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Unified enantioselective total synthesis of 3,6-dioxygenated diketopiperazine natural products, diatretol and lepistamides A, B and C

Tetrahedron letters, 2021-03, Vol.67, p.152895, Article 152895

2021

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An efflux pump deletion mutant enabling the discovery of a macrolide as an overlooked anti-P. aeruginosa active compound

Journal of antibiotics, 2023-05, Vol.76 (5), p.301-303

2023

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Nanaomycin H: A new nanaomycin analog

Journal of bioscience and bioengineering, 2017-06, Vol.123 (6), p.765-770

2017

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Synthesis and biological evaluation of burnettiene A derivatives enabling discovery of novel fungicide candidates

Journal of Pesticide Science, 2024-08, Article D24-014

2024

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Binding Mode-Based Physicochemical Screening Method Using d‑Ala‑d‑Ala Silica Gel and Chemical Modification Approach to Facilitate Discovery of New Macrolactams, Banglactams A and B, from Nonomuraea bangladeshensis K18–0086

ACS omega, 2024-04, Vol.9 (15), p.17415-17422

2024

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Design and Synthesis of d‑Ala‑d‑Ala Silica Gel for a Binding Mode-Based Physicochemical Screening Method

ACS omega, 2023-10, Vol.8 (42), p.39035-39040

2023

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Total Syntheses of the Marine Polyketide Hippolachnin

Yūki gōsei kagaku kyōkaishi, 2020-09, Vol.78 (9), p.901-903

Kimishima, Aoi

2020

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Rediscovery of Tetronomycin as a Broad-Spectrum and Potent Antibiotic against Drug-Resistant Gram-Positive Bacteria

ACS omega, 2023-03, Vol.8 (12), p.11556-11563

2023

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Toward the total synthesis of luminamicin; an anaerobic antibiotic: construction of highly functionalized cis-decalin containing a bridged ether moiety

Journal of antibiotics, 2018-02, Vol.71 (2), p.268-272

2018

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Toward the total synthesis of Luminamicin: construction of 14-membered lactone framework possessing versatile enol ether moiety

Tetrahedron letters, 2012-06, Vol.53 (23), p.2813-2816

2012

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Total Synthesis of Herquline B and C

Journal of the American Chemical Society, 2019-01, Vol.141 (1), p.25-28

2019

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Efflux pump inhibitor, phenylalanine-arginine beta-naphthylamide analog potentiates the activity of 5-O-mycaminosyltylonolide for multi-drug resistant Pseudomonas aeruginosa

Journal of antibiotics, 2024-05, Vol.77 (5), p.331-333

2024

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Emblestatin: a new peptide antibiotic from Embleya scabrispora K20-0267

Journal of antibiotics, 2023-10, Vol.76 (10), p.592-597

2023

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Total Synthesis of Fusaramin, Enabling Stereochemical Elucidation, Structure–Activity Relationship, and Uncovering the Hidden Antimicrobial Activity against Plant Pathogenic Fungi

Organic letters, 2024-01, Vol.26 (3), p.597-601

2024

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Re-discovery of MS-347a as a fungicide candidate through a new drug discovery platform with a multidrug-sensitive Saccharomyces cerevisiae screening system and the introduction of a global secondary metabolism regulator, laeA gene

Bioscience, biotechnology, and biochemistry, 2024-06, Vol.88 (7), p.824-829

2024

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Isolation of microorganisms from the feces of Kitasato Yakumo beef cattle as bioactive natural product producers

Bioscience, biotechnology, and biochemistry, 2024-09, Vol.88 (10), p.1242-1246

2024

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The potentiation activity of β-lactam by phomoidrides and oxasetin against methicillin-resistant Staphylococcus aureus

Journal of antibiotics, 2024-03, Vol.77 (3), p.185-188

2024

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PurA is the main target of aurodox, a type III secretion system inhibitor

Proceedings of the National Academy of Sciences - PNAS, 2024-04, Vol.121 (17), p.e2322363121

2024

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Discoveries and Syntheses of Highly Potent Antimalarial Troponoids

Comprehensive analysis of biosynthetic gene clusters in bacteria and discovery of Tumebacillus as a potential producer of natural products

A new tetronomycin analog, broad‐spectrum and potent antibiotic against drug‐resistant Gram‐positive bacteria

Sesquicillin F, a new insecticidal meroterpenoid produced by Mariannaea macrochlamydospora FKI-4735

Pd-catalyzed Regio- and Stereoselective Hydrostannylation of an Alkyl Ethynyl Ether/One-Pot Stille Coupling Enables the Synthesis of 14-Membered Macrolactone of Luminamicin

Total Syntheses and Chemical Biology Studies of Hymeglusin and Fusarilactone A, Novel Circumventors of β‐Lactam Drug Resistance in Methicillin‐Resistant Staphylococcus aureus

Traminines A and B, produced by Fusarium concentricum, inhibit oxidative phosphorylation in Saccharomyces cerevisiae mitochondria

Unified enantioselective total synthesis of 3,6-dioxygenated diketopiperazine natural products, diatretol and lepistamides A, B and C

An efflux pump deletion mutant enabling the discovery of a macrolide as an overlooked anti-P. aeruginosa active compound

Nanaomycin H: A new nanaomycin analog

Synthesis and biological evaluation of burnettiene A derivatives enabling discovery of novel fungicide candidates

Binding Mode-Based Physicochemical Screening Method Using d‑Ala‑d‑Ala Silica Gel and Chemical Modification Approach to Facilitate Discovery of New Macrolactams, Banglactams A and B, from Nonomuraea bangladeshensis K18–0086

Design and Synthesis of d‑Ala‑d‑Ala Silica Gel for a Binding Mode-Based Physicochemical Screening Method

Total Syntheses of the Marine Polyketide Hippolachnin

Rediscovery of Tetronomycin as a Broad-Spectrum and Potent Antibiotic against Drug-Resistant Gram-Positive Bacteria

Toward the total synthesis of luminamicin; an anaerobic antibiotic: construction of highly functionalized cis-decalin containing a bridged ether moiety

Toward the total synthesis of Luminamicin: construction of 14-membered lactone framework possessing versatile enol ether moiety

Total Synthesis of Herquline B and C

Efflux pump inhibitor, phenylalanine-arginine beta-naphthylamide analog potentiates the activity of 5-O-mycaminosyltylonolide for multi-drug resistant Pseudomonas aeruginosa

Emblestatin: a new peptide antibiotic from Embleya scabrispora K20-0267

Total Synthesis of Fusaramin, Enabling Stereochemical Elucidation, Structure–Activity Relationship, and Uncovering the Hidden Antimicrobial Activity against Plant Pathogenic Fungi

Re-discovery of MS-347a as a fungicide candidate through a new drug discovery platform with a multidrug-sensitive Saccharomyces cerevisiae screening system and the introduction of a global secondary metabolism regulator, laeA gene

Isolation of microorganisms from the feces of Kitasato Yakumo beef cattle as bioactive natural product producers

The potentiation activity of β-lactam by phomoidrides and oxasetin against methicillin-resistant Staphylococcus aureus

PurA is the main target of aurodox, a type III secretion system inhibitor

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