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Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns

Cell, 2017-10, Vol.171 (2), p.321-330.e14

2017

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Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes

Cell metabolism, 2020-05, Vol.31 (5), p.1017-1031.e4

2020

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A genetic strategy to measure circulating Drosophila insulin reveals genes regulating insulin production and secretion

PLoS genetics, 2014-08, Vol.10 (8), p.e1004555-e1004555

2014

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Gene Regulatory Networks Governing Pancreas Development

Developmental cell, 2013-04, Vol.25 (1), p.5-13

2013

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A genetic strategy to measure insulin signaling regulation and physiology in Drosophila

PLoS genetics, 2023-02, Vol.19 (2), p.e1010619-e1010619

2023

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Using Drosophila to discover mechanisms underlying type 2 diabetes

Disease models & mechanisms, 2016-04, Vol.9 (4), p.365-376

2016

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Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function

Cell metabolism, 2016-05, Vol.23 (5), p.909-920

2016

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Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

Nature genetics, 2011-07, Vol.43 (7), p.621-629

2011

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Targeting SOX17 in Human Embryonic Stem Cells Creates Unique Strategies for Isolating and Analyzing Developing Endoderm

Cell stem cell, 2011-03, Vol.8 (3), p.335-346

2011

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Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing

Genes & development, 2015-07, Vol.29 (14), p.1576-1585

2015

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Suppression of Insulin Production and Secretion by a Decretin Hormone

Cell metabolism, 2015-02, Vol.21 (2), p.323-334

2015

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Single-cell transcriptome and accessible chromatin dynamics during endocrine pancreas development

Proceedings of the National Academy of Sciences - PNAS, 2022-06, Vol.119 (26), p.e2201267119

2022

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CRISPR-based genome editing in primary human pancreatic islet cells

Nature communications, 2021-04, Vol.12 (1), p.2397-2397, Article 2397

2021

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Neonatal β Cell Development in Mice and Humans Is Regulated by Calcineurin/NFAT

Developmental cell, 2012-07, Vol.23 (1), p.21-34

2012

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Discovering human diabetes-risk gene function with genetics and physiological assays

Nature communications, 2018-09, Vol.9 (1), p.3855-11, Article 3855

2018

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Molecular and genetic regulation of pig pancreatic islet cell development

Development (Cambridge), 2020-03, Vol.147 (6)

2020

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Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells

Nature communications, 2017-03, Vol.8 (1), p.14686-14686, Article 14686

2017

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Ablation of Insulin-Producing Neurons in Flies: Growth and Diabetic Phenotypes

Science (American Association for the Advancement of Science), 2002-05, Vol.296 (5570), p.1118-1120

2002

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Conserved mechanisms of glucose sensing and regulation by Drosophila corpora cardiaca cells

Nature, 2004-09, Vol.431 (7006), p.316-320

2004

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Cryopreservation and post-thaw characterization of dissociated human islet cells

PloS one, 2022-01, Vol.17 (1), p.e0263005-e0263005

2022

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Wnt signaling regulates pancreatic β cell proliferation

Proceedings of the National Academy of Sciences - PNAS, 2007-04, Vol.104 (15), p.6247-6252

2007

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An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development

PLoS genetics, 2014-10, Vol.10 (10), p.e1004645-e1004645

2014

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US–Guided, Direct Puncture Retrograde Thoracic Duct Access, Lymphangiography, and Embolization: Feasibility and Efficacy

Journal of vascular and interventional radiology, 2016-12, Vol.27 (12), p.1890-1896

2016

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Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells

eLife, 2013-11, Vol.2, p.e00940-e00940

2013

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NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21

Nature, 2006-06, Vol.441 (7093), p.595-600

2006

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Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns

Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes

A genetic strategy to measure circulating Drosophila insulin reveals genes regulating insulin production and secretion

Gene Regulatory Networks Governing Pancreas Development

A genetic strategy to measure insulin signaling regulation and physiology in Drosophila

Using Drosophila to discover mechanisms underlying type 2 diabetes

Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

Targeting SOX17 in Human Embryonic Stem Cells Creates Unique Strategies for Isolating and Analyzing Developing Endoderm

Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing

Suppression of Insulin Production and Secretion by a Decretin Hormone

Single-cell transcriptome and accessible chromatin dynamics during endocrine pancreas development

CRISPR-based genome editing in primary human pancreatic islet cells

Neonatal β Cell Development in Mice and Humans Is Regulated by Calcineurin/NFAT

Discovering human diabetes-risk gene function with genetics and physiological assays

Molecular and genetic regulation of pig pancreatic islet cell development

Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells

Ablation of Insulin-Producing Neurons in Flies: Growth and Diabetic Phenotypes

Conserved mechanisms of glucose sensing and regulation by Drosophila corpora cardiaca cells

Cryopreservation and post-thaw characterization of dissociated human islet cells

Wnt signaling regulates pancreatic β cell proliferation

An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development

US–Guided, Direct Puncture Retrograde Thoracic Duct Access, Lymphangiography, and Embolization: Feasibility and Efficacy

Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21

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