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Pharmacology of Antagonism of GPCR

Biological and Pharmaceutical Bulletin, 2022/06/01, Vol.45(6), pp.669-674

2022

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Gα12/13 signaling in metabolic diseases

Experimental and Molecular Medicine, 2020, 52(0), , pp.1-15

2020

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Scaffolding of Keap1 to the Actin Cytoskeleton Controls the Function of Nrf2 as Key Regulator of Cytoprotective Phase 2 Genes

Proceedings of the National Academy of Sciences - PNAS, 2004-02, Vol.101 (7), p.2046-2051

2004

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Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression

Gut, 2019-04, Vol.68 (4), p.708-720

2019

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Hypergravity Load Modulates Acetaminophen Nephrotoxicity via Endoplasmic Reticulum Stress in Association with Hepatic microRNA-122 Expression

International journal of molecular sciences, 2021-05, Vol.22 (9), p.4901

2021

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Endoplasmic Reticulum Stress in Hepatic Stellate Cells Promotes Liver Fibrosis via PERK-Mediated Degradation of HNRNPA1 and Up-regulation of SMAD2

Gastroenterology (New York, N.Y. 1943), 2016, Vol.150 (1), p.181-193.e8

2016

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3,3'-Diindolylmethane Suppresses the Inflammatory Response to Lipopolysaccharide in Murine Macrophages

The Journal of nutrition, 2008, Vol.138 (1), p.17-23

2008

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Role of non-coding RNAs in liver disease progression to hepatocellular carcinoma

Archives of Pharmacal Research, 2019, 42(1), , pp.48-62

2019

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FXR Inhibits Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome in Hepatocytes and Ameliorates Liver Injury

Cell reports (Cambridge), 2018-09, Vol.24 (11), p.2985-2999

2018

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Endoplasmic reticulum stress and autophagy dysregulation in alcoholic and non-alcoholic liver diseases

Clinical and Molecular Hepatology, 2020, 26(4), , pp.715-727

2020

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Intestinal Inflammation and Regeneration-Interdigitating Processes Controlled by Dietary Lipids in Inflammatory Bowel Disease

International journal of molecular sciences, 2024-01, Vol.25 (2), p.1311

2024

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Decrease of microRNA-122 causes hepatic insulin resistance by inducing protein tyrosine phosphatase 1B, which is reversed by licorice flavonoid

Hepatology (Baltimore, Md.), 2012-12, Vol.56 (6), p.2209-2220

2012

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Resveratrol Protects Mitochondria against Oxidative Stress through AMP-Activated Protein Kinase-Mediated Glycogen Synthase Kinase-3β Inhibition Downstream of Poly(ADP-ribose)polymerase-LKB1 Pathway

Molecular pharmacology, 2009-10, Vol.76 (4), p.884-895

2009

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Glucocorticoid Receptor (GR)-Associated SMRT Binding to C/EBPβ TAD and Nrf2 Neh4/5: Role of SMRT Recruited to GR in GSTA2 Gene Repression

Molecular and Cellular Biology, 2005-05, Vol.25 (10), p.4150-4165

2005

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Kidney: Toxicological Assessment

Kim, Sang Geon

1, 2013

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Gα12 and endoplasmic reticulum stress-mediated pyroptosis in a single cycle of dextran sulfate-induced mouse colitis

Scientific reports, 2024-03, Vol.14 (1), p.6335-6335, Article 6335

2024

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Roles of toll-like receptors in Cancer: A double-edged sword for defense and offense

Archives of Pharmacal Research, 2012, 35(8), , pp.1297-1316

2012

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Hepatic Gα13 ablation shifts region-specific colonic inflammatory status by modulating the bile acid synthetic pathway in mice

Scientific reports, 2024-08, Vol.14 (1), p.19580-18

2024

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Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D

Nature communications, 2022-10, Vol.13 (1), p.6080-19, Article 6080

2022

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Discovery of an integrative network of microRNAs and transcriptomics changes for acute kidney injury

Kidney international, 2014-11, Vol.86 (5), p.943-953

2014

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Identification of a novel class of dithiolethiones that prevent hepatic insulin resistance via the adenosine monophosphate–activated protein kinase–p70 ribosomal S6 kinase‐1 pathway

Hepatology (Baltimore, Md.), 2007-09, Vol.46 (3), p.730-739

2007

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AMPK-mediated GSK3β inhibition by isoliquiritigenin contributes to protecting mitochondria against iron-catalyzed oxidative stress

Biochemical pharmacology, 2010-05, Vol.79 (9), p.1352-1362

2010

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Dysregulated Liver Metabolism and Polycystic Ovarian Syndrome

International journal of molecular sciences, 2023-04, Vol.24 (8), p.7454

2023

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Auto-regulation of Secretory Flux by Sensing and Responding to the Folded Cargo Protein Load in the Endoplasmic Reticulum

Cell, 2019-03, Vol.176 (6), p.1461-1476.e23

2019

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AMPK-Dependent Metabolic Regulation by PPAR Agonists

PPAR Research, 2010-01, Vol.2010 (2010), p.1-10

2010

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Pharmacology of Antagonism of GPCR

Gα12/13 signaling in metabolic diseases

Scaffolding of Keap1 to the Actin Cytoskeleton Controls the Function of Nrf2 as Key Regulator of Cytoprotective Phase 2 Genes

Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression

Hypergravity Load Modulates Acetaminophen Nephrotoxicity via Endoplasmic Reticulum Stress in Association with Hepatic microRNA-122 Expression

Endoplasmic Reticulum Stress in Hepatic Stellate Cells Promotes Liver Fibrosis via PERK-Mediated Degradation of HNRNPA1 and Up-regulation of SMAD2

3,3'-Diindolylmethane Suppresses the Inflammatory Response to Lipopolysaccharide in Murine Macrophages

Role of non-coding RNAs in liver disease progression to hepatocellular carcinoma

FXR Inhibits Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome in Hepatocytes and Ameliorates Liver Injury

Endoplasmic reticulum stress and autophagy dysregulation in alcoholic and non-alcoholic liver diseases

Intestinal Inflammation and Regeneration-Interdigitating Processes Controlled by Dietary Lipids in Inflammatory Bowel Disease

Decrease of microRNA-122 causes hepatic insulin resistance by inducing protein tyrosine phosphatase 1B, which is reversed by licorice flavonoid

Resveratrol Protects Mitochondria against Oxidative Stress through AMP-Activated Protein Kinase-Mediated Glycogen Synthase Kinase-3β Inhibition Downstream of Poly(ADP-ribose)polymerase-LKB1 Pathway

Glucocorticoid Receptor (GR)-Associated SMRT Binding to C/EBPβ TAD and Nrf2 Neh4/5: Role of SMRT Recruited to GR in GSTA2 Gene Repression

Kidney: Toxicological Assessment

Gα12 and endoplasmic reticulum stress-mediated pyroptosis in a single cycle of dextran sulfate-induced mouse colitis

Roles of toll-like receptors in Cancer: A double-edged sword for defense and offense

Hepatic Gα13 ablation shifts region-specific colonic inflammatory status by modulating the bile acid synthetic pathway in mice

Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D

Discovery of an integrative network of microRNAs and transcriptomics changes for acute kidney injury

Identification of a novel class of dithiolethiones that prevent hepatic insulin resistance via the adenosine monophosphate–activated protein kinase–p70 ribosomal S6 kinase‐1 pathway

AMPK-mediated GSK3β inhibition by isoliquiritigenin contributes to protecting mitochondria against iron-catalyzed oxidative stress

Dysregulated Liver Metabolism and Polycystic Ovarian Syndrome

Auto-regulation of Secretory Flux by Sensing and Responding to the Folded Cargo Protein Load in the Endoplasmic Reticulum

AMPK-Dependent Metabolic Regulation by PPAR Agonists

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