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Notch signaling during cell fate determination in the inner ear

Seminars in cell & developmental biology, 2013-05, Vol.24 (5), p.470-479

Kiernan, Amy E.

2013

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The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear

PLoS computational biology, 2006-01, Vol.2 (1), p.e4-e4

2006

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Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear

Proceedings of the National Academy of Sciences - PNAS, 2010-09, Vol.107 (36), p.15798-15803

2010

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Ectopic expression of activated notch or SOX2 reveals similar and unique roles in the development of the sensory cell progenitors in the mammalian inner ear

The Journal of neuroscience, 2013-10, Vol.33 (41), p.16146-16157

2013

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SOX2 is required for inner ear neurogenesis

Scientific reports, 2017-06, Vol.7 (1), p.4086-11, Article 4086

2017

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Deletion of the Notch ligand Jagged1 during cochlear maturation leads to inner hair cell defects and hearing loss

Cell death & disease, 2022-11, Vol.13 (11), p.971-971, Article 971

2022

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The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear

Development (Cambridge), 2005-10, Vol.132 (19), p.4353-4362

2005

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Ciliary margin-derived BMP4 does not have a major role in ocular development

PloS one, 2018-05, Vol.13 (5), p.e0197048-e0197048

2018

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Increased central auditory gain in 5xFAD Alzheimer's disease mice as an early biomarker candidate for Alzheimer's disease diagnosis

Frontiers in neuroscience, 2023-05, Vol.17, p.1106570-1106570

2023

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Sox2 is required for sensory organ development in the mammalian inner ear

Nature, 2005-04, Vol.434 (7036), p.1031-1035

2005

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Activated notch causes deafness by promoting a supporting cell phenotype in developing auditory hair cells

PloS one, 2014-09, Vol.9 (9), p.e108160-e108160

2014

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Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye

Proceedings of the National Academy of Sciences - PNAS, 2013-05, Vol.110 (22), p.8966-8971

2013

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Deletion of Notch1 during Cochlear Maturation Leads to Rapid Supporting Cell Death and Profound Deafness

The Journal of neuroscience, 2023-01, Vol.43 (2), p.199-210

2023

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Mutanlallemand (mtl) and Belly Spot and Deafness (bsd) are two new mutations of Lmx1a causing severe cochlear and vestibular defects

PloS one, 2012-11, Vol.7 (11), p.e51065-e51065

2012

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Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice

Development (Cambridge), 2003-05, Vol.130 (9), p.2013-2025

2003

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The paintfill method as a tool for analyzing the three-dimensional structure of the inner ear

Brain research, 2006-05, Vol.1091 (1), p.270-276

Kiernan, Amy E.

2006

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SOX2 is required for inner ear growth and cochlear nonsensory formation before sensory development

Development (Cambridge), 2019-06, Vol.146 (13)

2019

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The Notch Ligand Jagged1 is Required for Inner Ear Sensory Development

Proceedings of the National Academy of Sciences - PNAS, 2001-03, Vol.98 (7), p.3873-3878

2001

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Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development

Developmental biology, 2020-06, Vol.462 (1), p.74-84

2020

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Deletion of a Long-Range Dlx5 Enhancer Disrupts Inner Ear Development in Mice

Genetics (Austin), 2018-03, Vol.208 (3), p.1165-1179

2018

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Trabecular meshwork morphogenesis: A comparative analysis of wildtype and anterior segment dysgenesis mouse models

Experimental eye research, 2018-05, Vol.170, p.81-91

2018

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Molecular Genetics of Pattern Formation in the Inner Ear: Do Compartment Boundaries Play a Role?

Proceedings of the National Academy of Sciences - PNAS, 2000-10, Vol.97 (22), p.11700-11706

2000

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Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities

Experimental eye research, 2015-12, Vol.141, p.42-56

2015

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LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea

The Journal of neuroscience, 2014-07, Vol.34 (30), p.10072-10077

2014

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Genetic Background Modifies Inner Ear and Eye Phenotypes of Jag1 Heterozygous Mice

Genetics (Austin), 2007-09, Vol.177 (1), p.307-311

2007

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Notch signaling during cell fate determination in the inner ear

The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear

Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear

Ectopic expression of activated notch or SOX2 reveals similar and unique roles in the development of the sensory cell progenitors in the mammalian inner ear

SOX2 is required for inner ear neurogenesis

Deletion of the Notch ligand Jagged1 during cochlear maturation leads to inner hair cell defects and hearing loss

The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear

Ciliary margin-derived BMP4 does not have a major role in ocular development

Increased central auditory gain in 5xFAD Alzheimer's disease mice as an early biomarker candidate for Alzheimer's disease diagnosis

Sox2 is required for sensory organ development in the mammalian inner ear

Activated notch causes deafness by promoting a supporting cell phenotype in developing auditory hair cells

Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye

Deletion of Notch1 during Cochlear Maturation Leads to Rapid Supporting Cell Death and Profound Deafness

Mutanlallemand (mtl) and Belly Spot and Deafness (bsd) are two new mutations of Lmx1a causing severe cochlear and vestibular defects

Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice

The paintfill method as a tool for analyzing the three-dimensional structure of the inner ear

SOX2 is required for inner ear growth and cochlear nonsensory formation before sensory development

The Notch Ligand Jagged1 is Required for Inner Ear Sensory Development

Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development

Deletion of a Long-Range Dlx5 Enhancer Disrupts Inner Ear Development in Mice

Trabecular meshwork morphogenesis: A comparative analysis of wildtype and anterior segment dysgenesis mouse models

Molecular Genetics of Pattern Formation in the Inner Ear: Do Compartment Boundaries Play a Role?

Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities

LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea

Genetic Background Modifies Inner Ear and Eye Phenotypes of Jag1 Heterozygous Mice

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