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Molecular Determinants of Dofetilide Block of HERG K+ Channels

Circulation research, 1998-02, Vol.82 (3), p.386-395

1998

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The antidepressant drug fluoxetine is an inhibitor of human ether-a-go-go-related gene (HERG) potassium channels

The Journal of pharmacology and experimental therapeutics, 2002-02, Vol.300 (2), p.543

2002

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Adrenergic regulation of the rapid component of the cardiac delayed rectifier potassium current, IKr, and the underlying hERG ion channel

Basic research in cardiology, 2004-07, Vol.99 (4), p.279

2004

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Deletion of Protein Kinase A Phosphorylation Sites in the HERG Potassium Channel Inhibits Activation Shift by Protein Kinase A

The Journal of biological chemistry, 1999-09, Vol.274 (39), p.27457-27462

1999

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High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872

The Journal of pharmacology and experimental therapeutics, 2001-05, Vol.297 (2), p.753

2001

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Inhibition of cardiac HERG channels by grapefruit flavonoid naringenin: implications for the influence of dietary compounds on cardiac repolarisation

Naunyn-Schmiedeberg's archives of pharmacology, 2005-06, Vol.371 (6), p.516-525

2005

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HERG Potassium Channel Activation Is Shifted by Phorbol Esters via Protein Kinase A-dependent Pathways

The Journal of biological chemistry, 1998-09, Vol.273 (39), p.25285-25291

1998

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Inhibition of cardiac HERG potassium channels by the atypical antidepressant trazodone

Naunyn-Schmiedeberg's archives of pharmacology, 2004-08, Vol.370 (2), p.146-156

2004

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Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine

Naunyn-Schmiedeberg's archives of pharmacology, 2003-11, Vol.368 (5), p.404-414

2003

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Comparison of Binding and Block Produced by Alternatively Spliced Kvβ1 Subunits

The Journal of biological chemistry, 1996-11, Vol.271 (45), p.28311-28317

1996

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Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by ?1A-adrenoceptors

Journal of molecular medicine (Berlin, Germany), 2004-12, Vol.82 (12), p.826-837

2004

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Defective protein trafficking in hERG-associated hereditary long QT syndrome (LQT2): molecular mechanisms and restoration of intracellular protein processing

Cardiovascular research, 2003-11, Vol.60 (2), p.235-241

2003

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Human ?3-adrenoreceptors couple to KvLQT1/MinK potassium channels in Xenopus oocytes via protein kinase C phosphorylation of the KvLQT1 protein

Naunyn-Schmiedeberg's archives of pharmacology, 2003-08, Vol.368 (2), p.119-126

2003

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QTc prolongation by grapefruit juice and its potential pharmacological basis: HERG channel blockade by flavonoids

Circulation (New York, N.Y.), 2005-02, Vol.111 (7), p.835-838

2005

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Molecular physiology and pharmacology of HERG : Single-channel currents and block by dofetilide

Circulation (New York, N.Y.), 1996-11, Vol.94 (10), p.2572-2579

1996

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Regulation of the Cardiac Repolarizing HERG Potassium Channel by Protein Kinase A

Trends in cardiovascular medicine, 2000-07, Vol.10 (5), p.205-209

Kiehn, Johann

2000

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Rapid component IKr of the guinea-pig cardiac delayed rectifier K+ current is inhibited by β1-adrenoreceptor activation, via cAMP/protein kinase A-dependent pathways

Cardiovascular research, 2002-02, Vol.53 (2), p.355-362

Karle, C

2002

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Antiarrhythmic drug carvedilol inhibits HERG potassium channels

Cardiovascular research, 2001-02, Vol.49 (2), p.361-370

2001

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Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/minK potassium channels

British journal of pharmacology, 2003-11, Vol.140 (5), p.996-1002

2003

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Doxazosin induces apoptosis of cells expressing hERG K + channels

European journal of pharmacology, 2008-01, Vol.579 (1), p.98-103

2008

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Regulation of HERG potassium channel activation by protein kinase C independent of direct phosphorylation of the channel protein

Cardiovascular research, 2003-07, Vol.59 (1), p.14-26

2003

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Pathways of HERG inactivation

American journal of physiology. Heart and circulatory physiology, 1999-07, Vol.277 (1), p.H199-H210

1999

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Human cardiac inwardly rectifying current IKir2.2 is upregulated by activation of protein kinase A

Cardiovascular research, 2004-08, Vol.63 (3), p.520-527

2004

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Inhibitory effects of the class III antiarrhythmic drug amiodarone on cloned HERG potassium channels

Naunyn-Schmiedeberg's archives of pharmacology, 1999-03, Vol.359 (3), p.212-219

1999

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Direct block of hERG potassium channels by the protein kinase C inhibitor bisindolylmaleimide I (GF109203X)

Cardiovascular research, 2004-12, Vol.64 (3), p.467-476

2004

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Molecular Determinants of Dofetilide Block of HERG K+ Channels

The antidepressant drug fluoxetine is an inhibitor of human ether-a-go-go-related gene (HERG) potassium channels

Adrenergic regulation of the rapid component of the cardiac delayed rectifier potassium current, IKr, and the underlying hERG ion channel

Deletion of Protein Kinase A Phosphorylation Sites in the HERG Potassium Channel Inhibits Activation Shift by Protein Kinase A

High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872

Inhibition of cardiac HERG channels by grapefruit flavonoid naringenin: implications for the influence of dietary compounds on cardiac repolarisation

HERG Potassium Channel Activation Is Shifted by Phorbol Esters via Protein Kinase A-dependent Pathways

Inhibition of cardiac HERG potassium channels by the atypical antidepressant trazodone

Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine

Comparison of Binding and Block Produced by Alternatively Spliced Kvβ1 Subunits

Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by ?1A-adrenoceptors

Defective protein trafficking in hERG-associated hereditary long QT syndrome (LQT2): molecular mechanisms and restoration of intracellular protein processing

Human ?3-adrenoreceptors couple to KvLQT1/MinK potassium channels in Xenopus oocytes via protein kinase C phosphorylation of the KvLQT1 protein

QTc prolongation by grapefruit juice and its potential pharmacological basis: HERG channel blockade by flavonoids

Molecular physiology and pharmacology of HERG : Single-channel currents and block by dofetilide

Regulation of the Cardiac Repolarizing HERG Potassium Channel by Protein Kinase A

Rapid component IKr of the guinea-pig cardiac delayed rectifier K+ current is inhibited by β1-adrenoreceptor activation, via cAMP/protein kinase A-dependent pathways

Antiarrhythmic drug carvedilol inhibits HERG potassium channels

Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/minK potassium channels

Doxazosin induces apoptosis of cells expressing hERG K + channels

Regulation of HERG potassium channel activation by protein kinase C independent of direct phosphorylation of the channel protein

Pathways of HERG inactivation

Human cardiac inwardly rectifying current IKir2.2 is upregulated by activation of protein kinase A

Inhibitory effects of the class III antiarrhythmic drug amiodarone on cloned HERG potassium channels

Direct block of hERG potassium channels by the protein kinase C inhibitor bisindolylmaleimide I (GF109203X)

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