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Leveraging Polygenic Functional Enrichment to Improve GWAS Power

American journal of human genetics, 2019-01, Vol.104 (1), p.65-75

2019

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Probabilistic fine-mapping of transcriptome-wide association studies

Nature genetics, 2019-04, Vol.51 (4), p.675-682

2019

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Integrating functional data to prioritize causal variants in statistical fine-mapping studies

PLoS genetics, 2014-10, Vol.10 (10), p.e1004722-e1004722

2014

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Improved methods for multi-trait fine mapping of pleiotropic risk loci

Bioinformatics (Oxford, England), 2017-01, Vol.33 (2), p.248-255

2017

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Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data

American journal of human genetics, 2016-07, Vol.99 (1), p.139-153

2016

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Localizing Components of Shared Transethnic Genetic Architecture of Complex Traits from GWAS Summary Data

American journal of human genetics, 2020-06, Vol.106 (6), p.805-817

2020

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Phenotype-Specific Enrichment of Mendelian Disorder Genes near GWAS Regions across 62 Complex Traits

American journal of human genetics, 2018-10, Vol.103 (4), p.535-552

2018

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Methods for fine-mapping with chromatin and expression data

PLoS genetics, 2018-02, Vol.14 (2), p.e1007240-e1007240

2018

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Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies

American journal of human genetics, 2015-08, Vol.97 (2), p.260-271

2015

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Integrating Gene Expression with Summary Association Statistics to Identify Genes Associated with 30 Complex Traits

American journal of human genetics, 2017-03, Vol.100 (3), p.473-487

2017

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Mixed-model association for biobank-scale datasets

Nature genetics, 2018-07, Vol.50 (7), p.906-908

2018

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Enhanced Delivery and Potency of Self-Amplifying mRNA Vaccines by Electroporation in Situ

Vaccines (Basel), 2013-08, Vol.1 (3), p.367-383

2013

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Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies

American journal of human genetics, 2015-08, Vol.97 (2), p.353-353

2015

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Optimized In Vivo Transfer of Small Interfering RNA Targeting Dermal Tissue Using In Vivo Surface Electroporation

Molecular therapy. Nucleic acids, 2012-02, Vol.1 (2), p.e11-e11, Article e11

2012

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Optimization of electroporation-enhanced intradermal delivery of DNA vaccine using a minimally invasive surface device

Human gene therapy. Part B. Methods, 2012-06, Vol.23 (3), p.157

2012

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Identification of causal genes for complex traits

Bioinformatics (Oxford, England), 2015-06, Vol.31 (12), p.i206-i213

2015

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Enhanced methods to detect haplotypic effects on gene expression

Bioinformatics (Oxford, England), 2017-08, Vol.33 (15), p.2307-2313

2017

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Widespread Allelic Heterogeneity in Complex Traits

American journal of human genetics, 2017-05, Vol.100 (5), p.789-802

2017

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Mixed model association for biobank-scale data sets

Nature genetics, 2018-07, Vol.50 (7), p.906-908

2018

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Elucidating the Kinetics of Expression and Immune Cell Infiltration Resulting from Plasmid Gene Delivery Enhanced by Surface Dermal Electroporation

Vaccines (Basel), 2013-08, Vol.1 (3), p.384-397

2013

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Annotations capturing cell type-specific TF binding explain a large fraction of disease heritability

Human molecular genetics, 2020-05, Vol.29 (7), p.1057-1067

2020

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Genetic associations of breast and prostate cancer are enriched for regulatory elements identified in disease-related tissues

Human genetics, 2019-10, Vol.138 (10), p.1091-1104

2019

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Integrative Statistical Methods to Understand the Genetic Basis of Complex Traits

Kichaev, Gleb

2018

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ProQuest

PADRE: Pedigree-Aware Distant-Relationship Estimation

American journal of human genetics, 2016-07, Vol.99 (1), p.154-162

2016

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Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci

Human molecular genetics, 2016-12, Vol.25 (24), p.5500-5512

2016

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Leveraging Polygenic Functional Enrichment to Improve GWAS Power

Probabilistic fine-mapping of transcriptome-wide association studies

Integrating functional data to prioritize causal variants in statistical fine-mapping studies

Improved methods for multi-trait fine mapping of pleiotropic risk loci

Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data

Localizing Components of Shared Transethnic Genetic Architecture of Complex Traits from GWAS Summary Data

Phenotype-Specific Enrichment of Mendelian Disorder Genes near GWAS Regions across 62 Complex Traits

Methods for fine-mapping with chromatin and expression data

Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies

Integrating Gene Expression with Summary Association Statistics to Identify Genes Associated with 30 Complex Traits

Mixed-model association for biobank-scale datasets

Enhanced Delivery and Potency of Self-Amplifying mRNA Vaccines by Electroporation in Situ

Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies

Optimized In Vivo Transfer of Small Interfering RNA Targeting Dermal Tissue Using In Vivo Surface Electroporation

Optimization of electroporation-enhanced intradermal delivery of DNA vaccine using a minimally invasive surface device

Identification of causal genes for complex traits

Enhanced methods to detect haplotypic effects on gene expression

Widespread Allelic Heterogeneity in Complex Traits

Mixed model association for biobank-scale data sets

Elucidating the Kinetics of Expression and Immune Cell Infiltration Resulting from Plasmid Gene Delivery Enhanced by Surface Dermal Electroporation

Annotations capturing cell type-specific TF binding explain a large fraction of disease heritability

Genetic associations of breast and prostate cancer are enriched for regulatory elements identified in disease-related tissues

Integrative Statistical Methods to Understand the Genetic Basis of Complex Traits

PADRE: Pedigree-Aware Distant-Relationship Estimation

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci

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