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Small molecule innate immune modulators in cancer therapy

Frontiers in immunology, 2024-09, Vol.15, p.1395655

2024

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AVA-NP-695 Selectively Inhibits ENPP1 to Activate STING Pathway and Abrogate Tumor Metastasis in 4T1 Breast Cancer Syngeneic Mouse Model

Molecules (Basel, Switzerland), 2022-10, Vol.27 (19), p.6721

2022

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Inhibition of Extracellular Cathepsin D Reduces Hepatic Lipid Accumulation and Leads to Mild Changes in Inflammationin NASH Mice

Frontiers in immunology, 2021-07, Vol.12, p.675535-675535

2021

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1041 Discovery of a potential first-in-class small molecule inhibitor of ADAR1 p150 which demonstrates strong anti-tumor efficacy in B16F10 syngeneic melanoma model

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1148-A1148

2023

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864 AVA-NP-695, a potent and selective ENPP1 inhibitor, demonstrates strong anti-tumor efficacy as monotherapy and in combination with radiation

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A963-A963

2023

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Inhibiting Extracellular Cathepsin D Reduces Hepatic Steatosis in Sprague⁻Dawley Rats

Biomolecules (Basel, Switzerland), 2019-05, Vol.9 (5), p.171

2019

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Abstract 3244: AVA-NP-695, a potent and selective ENPP1 inhibitor, abrogates tumor metastasis in 4T1 syngeneic tumor model and demonstrates strong tumor regression when combined with radiation

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.3244-3244

2023

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Abstract 4484: Discovery of a potential first-in-class Za targeted small molecule inhibitor of ADAR1 p150 which demonstrates strong anti-tumor efficacy

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.4484-4484

2024

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Identification and structure-activity relationship studies of small molecule inhibitors of the human cathepsin D

Bioorganic & medicinal chemistry, 2021-01, Vol.29, p.115879-115879, Article 115879

2021

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Abstract 3095: Development of a novel ADAR1 inhibitor as a potent immunomodulator for the treatment of solid tumors

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.3095-3095

2023

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Design, synthesis and biological evaluation studies of novel small molecule ENPP1 inhibitors for cancer immunotherapy

Bioorganic chemistry, 2022-02, Vol.119, p.105549-105549, Article 105549

2022

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Microbial taxonomy in the era of OMICS: application of DNA sequences, computational tools and techniques

Antonie van Leeuwenhoek, 2017-10, Vol.110 (10), p.1357-1371

2017

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Proceedings of Third International Conference on Computing, Communications, and Cyber-Security: Ic4s 2021

1, 2022

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Microbial Genomics and Metagenomics in India: Explorations and Perspectives

Proceedings of the Indian National Science Academy, Part A: Physical sciences, 2019-12

2019

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Small molecule innate immune modulators in cancer therapy

AVA-NP-695 Selectively Inhibits ENPP1 to Activate STING Pathway and Abrogate Tumor Metastasis in 4T1 Breast Cancer Syngeneic Mouse Model

Inhibition of Extracellular Cathepsin D Reduces Hepatic Lipid Accumulation and Leads to Mild Changes in Inflammationin NASH Mice

1041 Discovery of a potential first-in-class small molecule inhibitor of ADAR1 p150 which demonstrates strong anti-tumor efficacy in B16F10 syngeneic melanoma model

864 AVA-NP-695, a potent and selective ENPP1 inhibitor, demonstrates strong anti-tumor efficacy as monotherapy and in combination with radiation

Inhibiting Extracellular Cathepsin D Reduces Hepatic Steatosis in Sprague⁻Dawley Rats

Abstract 3244: AVA-NP-695, a potent and selective ENPP1 inhibitor, abrogates tumor metastasis in 4T1 syngeneic tumor model and demonstrates strong tumor regression when combined with radiation

Abstract 4484: Discovery of a potential first-in-class Za targeted small molecule inhibitor of ADAR1 p150 which demonstrates strong anti-tumor efficacy

Identification and structure-activity relationship studies of small molecule inhibitors of the human cathepsin D

Abstract 3095: Development of a novel ADAR1 inhibitor as a potent immunomodulator for the treatment of solid tumors

Design, synthesis and biological evaluation studies of novel small molecule ENPP1 inhibitors for cancer immunotherapy

Microbial taxonomy in the era of OMICS: application of DNA sequences, computational tools and techniques

Proceedings of Third International Conference on Computing, Communications, and Cyber-Security: Ic4s 2021

Microbial Genomics and Metagenomics in India: Explorations and Perspectives

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