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Amplification of neurotoxic HTTex1 assemblies in human neurons

Neurobiology of disease, 2021-11, Vol.159, p.105517-105517, Article 105517

2021

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The role of IκB kinase complex in the neurobiology of Huntington's disease

Neurobiology of disease, 2011-08, Vol.43 (2), p.305-311

2011

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IKKβ signaling mediates metabolic changes in the hypothalamus of a Huntington disease mouse model

iScience, 2022-02, Vol.25 (2), p.103771-103771, Article 103771

2022

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Gut Microbiota as a Modifier of Huntington’s Disease Pathogenesis

Journal of Huntington's disease, 2024-07, Vol.13 (2), p.133-147

Khoshnan, Ali

2024

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Elevated IKKα accelerates the differentiation of human neuronal progenitor cells and induces MeCP2-dependent BDNF expression

PloS one, 2012-07, Vol.7 (7), p.e41794-e41794

2012

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Corrigendum: Gut bacteria regulate the pathogenesis of Huntington's disease in Drosophila model

Frontiers in neuroscience, 2022-10, Vol.16, p.991513-991513

2022

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Small, Seeding-Competent Huntingtin Fibrils Are Prominent Aggregate Species in Brains of zQ175 Huntington’s Disease Knock-in Mice

Frontiers in neuroscience, 2021-06, Vol.15, p.682172-682172

2021

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Gut Bacteria Regulate the Pathogenesis of Huntington’s Disease in Drosophila Model

Frontiers in neuroscience, 2022-06, Vol.16, p.902205-902205

2022

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Intrabodies Binding the Proline-Rich Domains of Mutant Huntingtin Increase Its Turnover and Reduce Neurotoxicity

The Journal of neuroscience, 2008-09, Vol.28 (36), p.9013-9020

2008

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Effects of Intracellular Expression of Anti-Huntingtin Antibodies of Various Specificities on Mutant Huntingtin Aggregation and Toxicity

Proceedings of the National Academy of Sciences - PNAS, 2002-01, Vol.99 (2), p.1002-1007

2002

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Hepatitis C Virus Core Protein Binds to the Cytoplasmic Domain of Tumor Necrosis Factor (TNF) Receptor 1 and Enhances TNF-Induced Apoptosis

Journal of Virology, 1998-05, Vol.72 (5), p.3691-3697

1998

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Elevated IKK[alpha] Accelerates the Differentiation of Human Neuronal Progenitor Cells and Induces MeCP2-Dependent BDNF Expression

PloS one, 2012-07, Vol.7 (7), p.e41794

2012

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IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

The Journal of cell biology, 2009-12, Vol.187 (7), p.1083-1099

2009

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IKKβ and mutant huntingtin interactions regulate the expression of IL-34: implications for microglial-mediated neurodegeneration in HD

Human molecular genetics, 2017-11, Vol.26 (21), p.4267-4277

2017

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Identification of distinct conformations associated with monomers and fibril assemblies of mutant huntingtin

Human molecular genetics, 2018-07, Vol.27 (13), p.2330-2343

2018

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Trichomonas vaginalis with a double-stranded RNA virus has upregulated levels of phenotypically variable immunogen mRNA

Journal of Virology, 1994-06, Vol.68 (6), p.4035-4038

1994

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DJ-1 modulates aggregation and pathogenesis in models of Huntington's disease

Human molecular genetics, 2014-02, Vol.23 (3), p.755-766

2014

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Activation of the IκB Kinase Complex and Nuclear Factor-κB Contributes to Mutant Huntingtin Neurotoxicity

The Journal of neuroscience, 2004-09, Vol.24 (37), p.7999-8008

2004

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IKKα and IKKβ Regulation of DNA Damage-Induced Cleavage of Huntingtin

PloS one, 2009-06, Vol.4 (6), p.e5768

2009

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IKKalpha and IKKbeta regulation of DNA damage-induced cleavage of huntingtin

PloS one, 2009-06, Vol.4 (6), p.e5768-e5768

2009

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The physical association of protein kinase C theta with a lipid raft-associated inhibitor of kappa B factor kinase (IKK) complex plays a role in the activation of the NF-kappa B cascade by TCR and CD28

The Journal of immunology (1950), 2000-12, Vol.165 (12), p.6933-6940

2000

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Neurotoxicity of manganese oxide nanomaterials

Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology, 2009-11, Vol.11 (8), p.1957-1969

2009

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IKK[alpha] and IKK[beta] Regulation of DNA Damage-Induced Cleavage of Huntingtin

PloS one, 2009-06, Vol.4 (6), p.e5768

2009

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Response Differences between Human CD4+ and CD8+ T-Cells during CD28 Costimulation: Implications for Immune Cell-Based Therapies and Studies Related to the Expansion of Double-Positive T-Cells during Aging

Clinical immunology (Orlando, Fla.), 2000-09, Vol.96 (3), p.187-197

2000

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Antibodies against huntingtin: production and screening of monoclonals and single-chain recombinant forms

Methods in molecular biology (Clifton, N.J.), 2004, Vol.277, p.87

2004

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Amplification of neurotoxic HTTex1 assemblies in human neurons

The role of IκB kinase complex in the neurobiology of Huntington's disease

IKKβ signaling mediates metabolic changes in the hypothalamus of a Huntington disease mouse model

Gut Microbiota as a Modifier of Huntington’s Disease Pathogenesis

Elevated IKKα accelerates the differentiation of human neuronal progenitor cells and induces MeCP2-dependent BDNF expression

Corrigendum: Gut bacteria regulate the pathogenesis of Huntington's disease in Drosophila model

Small, Seeding-Competent Huntingtin Fibrils Are Prominent Aggregate Species in Brains of zQ175 Huntington’s Disease Knock-in Mice

Gut Bacteria Regulate the Pathogenesis of Huntington’s Disease in Drosophila Model

Intrabodies Binding the Proline-Rich Domains of Mutant Huntingtin Increase Its Turnover and Reduce Neurotoxicity

Effects of Intracellular Expression of Anti-Huntingtin Antibodies of Various Specificities on Mutant Huntingtin Aggregation and Toxicity

Hepatitis C Virus Core Protein Binds to the Cytoplasmic Domain of Tumor Necrosis Factor (TNF) Receptor 1 and Enhances TNF-Induced Apoptosis

Elevated IKK[alpha] Accelerates the Differentiation of Human Neuronal Progenitor Cells and Induces MeCP2-Dependent BDNF Expression

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

IKKβ and mutant huntingtin interactions regulate the expression of IL-34: implications for microglial-mediated neurodegeneration in HD

Identification of distinct conformations associated with monomers and fibril assemblies of mutant huntingtin

Trichomonas vaginalis with a double-stranded RNA virus has upregulated levels of phenotypically variable immunogen mRNA

DJ-1 modulates aggregation and pathogenesis in models of Huntington's disease

Activation of the IκB Kinase Complex and Nuclear Factor-κB Contributes to Mutant Huntingtin Neurotoxicity

IKKα and IKKβ Regulation of DNA Damage-Induced Cleavage of Huntingtin

IKKalpha and IKKbeta regulation of DNA damage-induced cleavage of huntingtin

The physical association of protein kinase C theta with a lipid raft-associated inhibitor of kappa B factor kinase (IKK) complex plays a role in the activation of the NF-kappa B cascade by TCR and CD28

Neurotoxicity of manganese oxide nanomaterials

IKK[alpha] and IKK[beta] Regulation of DNA Damage-Induced Cleavage of Huntingtin

Response Differences between Human CD4+ and CD8+ T-Cells during CD28 Costimulation: Implications for Immune Cell-Based Therapies and Studies Related to the Expansion of Double-Positive T-Cells during Aging

Antibodies against huntingtin: production and screening of monoclonals and single-chain recombinant forms

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