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Translation of new cancer treatments from pet dogs to humans

Nature reviews. Cancer, 2008-02, Vol.8 (2), p.147-156

2008

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Osteosarcoma

Journal of bone and mineral research, 2010-04, Vol.25 (4), p.683-691

2010

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Genomic landscapes of canine splenic angiosarcoma (hemangiosarcoma) contain extensive heterogeneity within and between patients

PloS one, 2022-07, Vol.17 (7), p.e0264986-e0264986

2022

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The Comparative Oncology Trials Consortium: using spontaneously occurring cancers in dogs to inform the cancer drug development pathway

PLoS medicine, 2009-10, Vol.6 (10), p.e1000161-e1000161

2009

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Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression

BMC genomics, 2009-12, Vol.10 (1), p.625-625

2009

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Feasibility of circulating tumor DNA analysis in dogs with naturally occurring malignant and benign splenic lesions

Scientific reports, 2022-04, Vol.12 (1), p.6337-6337, Article 6337

2022

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Combined SFK/MEK inhibition prevents metastatic outgrowth of dormant tumor cells

The Journal of clinical investigation, 2014-01, Vol.124 (1), p.156-168

2014

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Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (17), p.6323-6328

2014

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Prevalence and clinical features of thoracolumbar intervertebral disc‐associated epidural hemorrhage in dogs

Journal of veterinary internal medicine, 2022-07, Vol.36 (4), p.1365-1372

2022

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Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening

JNCI : Journal of the National Cancer Institute, 2011-06, Vol.103 (12), p.962-978

2011

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Type III Collagen Directs Stromal Organization and Limits Metastasis in a Murine Model of Breast Cancer

The American journal of pathology, 2015-05, Vol.185 (5), p.1471-1486

2015

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Guiding the Optimal Translation of New Cancer Treatments From Canine to Human Cancer Patients

Clinical cancer research, 2009-09, Vol.15 (18), p.5671-5677

2009

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Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton

Cancer research (Chicago, Ill.), 2008-08, Vol.68 (15), p.6241-6250

2008

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A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells

PLoS genetics, 2016-02, Vol.12 (2), p.e1005884-e1005884

2016

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Comparative Gene Expression Analyses Identify Luminal and Basal Subtypes of Canine Invasive Urothelial Carcinoma That Mimic Patterns in Human Invasive Bladder Cancer

PloS one, 2015-09, Vol.10 (9), p.e0136688-e0136688

2015

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Perspectives from man's best friend: National Academy of Medicine's Workshop on Comparative Oncology

Science translational medicine, 2016-02, Vol.8 (324), p.324ps5

2016

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The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

Nature medicine, 2004-02, Vol.10 (2), p.182-186

2004

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The dog as a cancer model

Nature biotechnology, 2006-09, Vol.24 (9), p.1065-1066

2006

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A potential early clinical phenotype of necrotizing meningoencephalitis in genetically at‐risk pug dogs

Journal of veterinary internal medicine, 2022-07, Vol.36 (4), p.1382-1389

2022

Volltextzugriff (PDF)

Assessing a Novel 3D Assay System for Drug Screening against OS Metastasis

Pharmaceuticals (Basel, Switzerland), 2021-09, Vol.14 (10), p.971

2021

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Leukocyte and cytokine variables in asymptomatic Pugs at genetic risk of necrotizing meningoencephalitis

Journal of veterinary internal medicine, 2021-11, Vol.35 (6), p.2846-2852

2021

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p53 Loss Increases the Osteogenic Differentiation of Bone Marrow Stromal Cells

Stem cells (Dayton, Ohio), 2015-04, Vol.33 (4), p.1304-1319

2015

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Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators

Nature medicine, 2004-02, Vol.10 (2), p.175-181

2004

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Translation of new cancer treatments from pet dogs to humans

Osteosarcoma

Genomic landscapes of canine splenic angiosarcoma (hemangiosarcoma) contain extensive heterogeneity within and between patients

The Comparative Oncology Trials Consortium: using spontaneously occurring cancers in dogs to inform the cancer drug development pathway

Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression

Feasibility of circulating tumor DNA analysis in dogs with naturally occurring malignant and benign splenic lesions

Combined SFK/MEK inhibition prevents metastatic outgrowth of dormant tumor cells

Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression

Prevalence and clinical features of thoracolumbar intervertebral disc‐associated epidural hemorrhage in dogs

Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening

Type III Collagen Directs Stromal Organization and Limits Metastasis in a Murine Model of Breast Cancer

Guiding the Optimal Translation of New Cancer Treatments From Canine to Human Cancer Patients

Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis

Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton

A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells

Comparative Gene Expression Analyses Identify Luminal and Basal Subtypes of Canine Invasive Urothelial Carcinoma That Mimic Patterns in Human Invasive Bladder Cancer

Perspectives from man's best friend: National Academy of Medicine's Workshop on Comparative Oncology

NCI Comparative Oncology Program Testing of Non-Camptothecin Indenoisoquinoline Topoisomerase I Inhibitors in Naturally Occurring Canine Lymphoma

The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

The dog as a cancer model

A potential early clinical phenotype of necrotizing meningoencephalitis in genetically at‐risk pug dogs

Assessing a Novel 3D Assay System for Drug Screening against OS Metastasis

Leukocyte and cytokine variables in asymptomatic Pugs at genetic risk of necrotizing meningoencephalitis

p53 Loss Increases the Osteogenic Differentiation of Bone Marrow Stromal Cells

Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators

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