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STING cyclic dinucleotide sensing originated in bacteria

Nature (London), 2020-10, Vol.586 (7829), p.429-433

2020

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Mechanism for recycling tRNAs on stalled ribosomes

Nature structural & molecular biology, 2019-05, Vol.26 (5), p.343-349

2019

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Cyclic CMP and cyclic UMP mediate bacterial immunity against phages

Cell, 2021-11, Vol.184 (23), p.5728-5739.e16

2021

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CBASS Immunity Uses CARF-Related Effectors to Sense 3′–5′- and 2′–5′-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection

Cell, 2020-07, Vol.182 (1), p.38-49.e17

2020

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Cryo-EM structure of an active bacterial TIR-STING filament complex

Nature (London), 2022-08, Vol.608 (7924), p.803-807

2022

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Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat

Nature communications, 2023-06, Vol.14 (1), p.3460-3460, Article 3460

2023

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Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation

Journal of the American Chemical Society, 2021-09, Vol.143 (34), p.13473-13477

2021

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Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase

Molecular and Cellular Biology, 2014-02, Vol.34 (3), p.362-373

2014

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Mechanism of catalysis, E2 recognition, and autoinhibition for the IpaH family of bacterial E3 ubiquitin ligases

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (6), p.1311-1316

2017

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Structural insights into metazoan pretargeting GET complexes

Nature structural & molecular biology, 2021-12, Vol.28 (12), p.1029-1037

2021

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Structural and Functional Analysis of Ubiquitin-based Inhibitors That Target the Backsides of E2 Enzymes

Journal of molecular biology, 2020-02, Vol.432 (4), p.952-966

2020

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FAM72A degrades UNG2 through the GID/CTLH complex to promote mutagenic repair during antibody maturation

Nature communications, 2024-08, Vol.15 (1), p.7541-19, Article 7541

2024

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The HisRS-like domain of GCN2 is a pseudoenzyme that can bind uncharged tRNA

Structure (London), 2024-06, Vol.32 (6), p.795-811.e6

2024

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Higher-Order Assembly of BRCC36–KIAA0157 Is Required for DUB Activity and Biological Function

Molecular cell, 2015-09, Vol.59 (6), p.970-983

2015

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Structure and dynamics of a pentameric KCTD5/CUL3/Gβγ E3 ubiquitin ligase complex

Proceedings of the National Academy of Sciences - PNAS, 2024-04, Vol.121 (17), p.e2315018121

2024

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Direct structural analysis of a single acyl carrier protein domain in fatty acid synthase from the fungus Saccharomyces cerevisiae

Communications biology, 2024-01, Vol.7 (1), p.92-92, Article 92

2024

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Conserved Structural Mechanisms for Autoinhibition in IpaH Ubiquitin Ligases

The Journal of biological chemistry, 2012-01, Vol.287 (1), p.268-275

2012

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Prostate cancer reshapes the secreted and extracellular vesicle urinary proteomes

Nature communications, 2024-06, Vol.15 (1), p.5069-16

2024

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Charting the conformational dynamics of human fatty acid synthase using cryo-EM

Biophysical journal, 2024-02, Vol.123 (3), p.159a-159a

2024

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Phosphorylated Serine Marks Proteins for Degradation By the Mitochondrial Matrix Protease, Clpxp

Blood, 2022-11, Vol.140 (Supplement 1), p.3023-3024

2022

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Serine Phosphorylation Marks Proteins for Degradation By the Mitochondrial Serine Protease Complex, Clpxp

Blood, 2023-11, Vol.142 (Supplement 1), p.5675-5675

2023

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Abstract 4834: Mitochondrial ClpXP degrades serine phosphorylated protein aggregates

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.4834-4834

2023

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Abstract 7053: Serine phosphorylation marks proteins for degradation by the mitochondrial matrix protease, ClpXP

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.7053-7053

2024

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Structure-Function Study of the IpaH Family of Bacterial E3 Ubiquitin Ligases

Keszei, Alexander Francis Attila

2017

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Empagliflozin does not change cardiac index nor systemic vascular resistance but rapidly improves left ventricular filling pressure in patients with type 2 diabetes: a randomized controlled study

Cardiovascular diabetology, 2021-01, Vol.20 (1), p.6-6, Article 6

2021

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STING cyclic dinucleotide sensing originated in bacteria

Mechanism for recycling tRNAs on stalled ribosomes

Cyclic CMP and cyclic UMP mediate bacterial immunity against phages

CBASS Immunity Uses CARF-Related Effectors to Sense 3′–5′- and 2′–5′-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection

Cryo-EM structure of an active bacterial TIR-STING filament complex

Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat

Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation

Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase

Mechanism of catalysis, E2 recognition, and autoinhibition for the IpaH family of bacterial E3 ubiquitin ligases

Structural insights into metazoan pretargeting GET complexes

Structural and Functional Analysis of Ubiquitin-based Inhibitors That Target the Backsides of E2 Enzymes

FAM72A degrades UNG2 through the GID/CTLH complex to promote mutagenic repair during antibody maturation

The HisRS-like domain of GCN2 is a pseudoenzyme that can bind uncharged tRNA

Higher-Order Assembly of BRCC36–KIAA0157 Is Required for DUB Activity and Biological Function

Structure and dynamics of a pentameric KCTD5/CUL3/Gβγ E3 ubiquitin ligase complex

Direct structural analysis of a single acyl carrier protein domain in fatty acid synthase from the fungus Saccharomyces cerevisiae

Conserved Structural Mechanisms for Autoinhibition in IpaH Ubiquitin Ligases

Prostate cancer reshapes the secreted and extracellular vesicle urinary proteomes

Charting the conformational dynamics of human fatty acid synthase using cryo-EM

Phosphorylated Serine Marks Proteins for Degradation By the Mitochondrial Matrix Protease, Clpxp

Serine Phosphorylation Marks Proteins for Degradation By the Mitochondrial Serine Protease Complex, Clpxp

Abstract 4834: Mitochondrial ClpXP degrades serine phosphorylated protein aggregates

Abstract 7053: Serine phosphorylation marks proteins for degradation by the mitochondrial matrix protease, ClpXP

Structure-Function Study of the IpaH Family of Bacterial E3 Ubiquitin Ligases

Empagliflozin does not change cardiac index nor systemic vascular resistance but rapidly improves left ventricular filling pressure in patients with type 2 diabetes: a randomized controlled study

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