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Differential Bile Acid Detection in Refractory GERD Patient Saliva Using a Simple and Sensitive Liquid Chromatography Tandem Mass Spectrometry Approach

Journal of clinical gastroenterology, 2022-03, Vol.56 (3), p.218-223

2022

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Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit

European journal of pharmacology, 2010-12, Vol.649 (1), p.328-335

2010

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Pharmacologic properties, metabolism, and disposition of linaclotide, a novel therapeutic peptide approved for the treatment of irritable bowel syndrome with constipation and chronic idiopathic constipation

The Journal of pharmacology and experimental therapeutics, 2013-01, Vol.344 (1), p.196-206

2013

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The Soluble Guanylate Cyclase Stimulator IWP-953 Increases Conventional Outflow Facility in Mouse Eyes

Investigative ophthalmology & visual science, 2016-03, Vol.57 (3), p.1317-1326

2016

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Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract

Life sciences (1973), 2010-05, Vol.86 (19), p.760-765

2010

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Gastrointestinal pain: Unraveling a novel endogenous pathway through uroguanylin/guanylate cyclase-C/cGMP activation

Pain (Amsterdam), 2013-09, Vol.154 (9), p.1820-1830

2013

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Linaclotide activates guanylate cyclase‐C/cGMP/protein kinase‐II‐dependent trafficking of CFTR in the intestine

Physiological reports, 2017-06, Vol.5 (11), p.e13299-n/a

2017

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MRP4 Modulation of the Guanylate Cyclase-C/cGMP Pathway: Effects on Linaclotide-Induced Electrolyte Secretion and cGMP Efflux

The Journal of pharmacology and experimental therapeutics, 2015-10, Vol.355 (1), p.48-56

2015

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Guanylate cyclase 2C agonism corrects CFTR mutants

JCI insight, 2017-10, Vol.2 (19)

2017

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Systematic discovery of new genes in the Saccharomyces cerevisiae genome

Genome research, 2003-02, Vol.13 (2), p.264-271

2003

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The Natriuretic Peptide Uroguanylin Elicits Physiologic Actions Through 2 Distinct Topoisomers

Hypertension (Dallas, Tex. 1979), 2009-05, Vol.53 (5), p.867-876

2009

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S513 Diagnostic Potential of Salivary Bile Acid for Laryngopharyngeal Reflux

The American journal of gastroenterology, 2023-10, Vol.118 (10S), p.S375-S376

2023

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Sa1212 THE G-PROTEIN-COUPLED BILE ACID RECEPTOR TGR5 (GPBAR1) IS EXPRESSED IN BOTH MUCOSA AND MUSCLE TISSUE FROM HUMAN LOWER ESOPHAGEAL SPHINCTER (LES)

Gastroenterology (New York, N.Y. 1943), 2020-05, Vol.158 (6), p.S-313-S-314

2020

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Sa1213 THE BILE ACID SEQUESTRANT COLESEVELAM AMELIORATES BILE ACID-DELAYED GASTRIC EMPTYING AND SLOWED SMALL INTESTINAL TRANSIT IN MICE

Gastroenterology (New York, N.Y. 1943), 2020-05, Vol.158 (6), p.S-314-S-314

2020

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Identification of potential cell‐surface proteins in Candida albicans and investigation of the role of a putative cell‐surface glycosidase in adhesion and virulence

Yeast (Chichester, England), 2004-03, Vol.21 (4), p.285-302

2004

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Pilot study evaluating salivary bile acids as a diagnostic biomarker of laryngopharyngeal reflux

Diseases of the esophagus, 2024-07, Vol.37 (7)

2024

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Pta1, a Component of Yeast CF II, Is Required for Both Cleavage and Poly(A) Addition of mRNA Precursor

Molecular and Cellular Biology, 1999-11, Vol.19 (11), p.7733-7740

1999

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1017 - Guanylate Cyclase 2C Activation Rescues the Folding Defect in F508Del CFTR

Gastroenterology (New York, N.Y. 1943), 2018-05, Vol.154 (6), p.S-193-S-193

2018

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Mo1886 Regulation of Linaclotide-Induced cGMP and Electrolyte Secretion by Multidrug Resistance-Associated Protein 4 (MRP4)

Gastroenterology (New York, N.Y. 1943), 2015-04, Vol.148 (4), p.S-735-S-735

2015

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A Comparison of the Physical and Pharmacological Properties of Plecanatide (SP-304) and the Human Hormone Uroguanylin: 1340

The American journal of gastroenterology, 2011-10, Vol.106, p.S513

2011

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Genomics strategies for antifungal drug discovery--from gene discovery to compound screening

Current pharmaceutical design, 2002-01, Vol.8 (13), p.1137-1154

2002

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Tu1211 IW-9179, a Phosphopeptide Designed to Target the Upper Gastrointestinal Tract, Is More Potent at Acidic pH and Is Rapidly Metabolized In Vitro in Rodent Intestinal Fluid

Gastroenterology (New York, N.Y. 1943), 2015-04, Vol.148 (4), p.S-823-S-823

2015

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956 IW-9179, a Potent Guanylate Cyclase-C (GC-C) Agonist, Improves Gastric Emptying In Vivo and Modulates Gastric Vagal Afferent Mechanosensitivity In Vitro

Gastroenterology (New York, N.Y. 1943), 2015-04, Vol.148 (4), p.S-186-S-186

2015

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The use of direct cDNA selection to rapidly and effectively identify genes in the fungus Aspergillus fumigatus

Fungal genetics and biology, 2002-06, Vol.36 (1), p.59-70

2002

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Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3'-end formation in yeast

Genes & development, 1997-10, Vol.11 (19), p.2545-2556

1997

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Differential Bile Acid Detection in Refractory GERD Patient Saliva Using a Simple and Sensitive Liquid Chromatography Tandem Mass Spectrometry Approach

Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit

Pharmacologic properties, metabolism, and disposition of linaclotide, a novel therapeutic peptide approved for the treatment of irritable bowel syndrome with constipation and chronic idiopathic constipation

The Soluble Guanylate Cyclase Stimulator IWP-953 Increases Conventional Outflow Facility in Mouse Eyes

Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract

Gastrointestinal pain: Unraveling a novel endogenous pathway through uroguanylin/guanylate cyclase-C/cGMP activation

Linaclotide activates guanylate cyclase‐C/cGMP/protein kinase‐II‐dependent trafficking of CFTR in the intestine

MRP4 Modulation of the Guanylate Cyclase-C/cGMP Pathway: Effects on Linaclotide-Induced Electrolyte Secretion and cGMP Efflux

Guanylate cyclase 2C agonism corrects CFTR mutants

Systematic discovery of new genes in the Saccharomyces cerevisiae genome

The Natriuretic Peptide Uroguanylin Elicits Physiologic Actions Through 2 Distinct Topoisomers

S513 Diagnostic Potential of Salivary Bile Acid for Laryngopharyngeal Reflux

Sa1212 THE G-PROTEIN-COUPLED BILE ACID RECEPTOR TGR5 (GPBAR1) IS EXPRESSED IN BOTH MUCOSA AND MUSCLE TISSUE FROM HUMAN LOWER ESOPHAGEAL SPHINCTER (LES)

Sa1213 THE BILE ACID SEQUESTRANT COLESEVELAM AMELIORATES BILE ACID-DELAYED GASTRIC EMPTYING AND SLOWED SMALL INTESTINAL TRANSIT IN MICE

Identification of potential cell‐surface proteins in Candida albicans and investigation of the role of a putative cell‐surface glycosidase in adhesion and virulence

Pilot study evaluating salivary bile acids as a diagnostic biomarker of laryngopharyngeal reflux

Pta1, a Component of Yeast CF II, Is Required for Both Cleavage and Poly(A) Addition of mRNA Precursor

1017 - Guanylate Cyclase 2C Activation Rescues the Folding Defect in F508Del CFTR

Mo1886 Regulation of Linaclotide-Induced cGMP and Electrolyte Secretion by Multidrug Resistance-Associated Protein 4 (MRP4)

A Comparison of the Physical and Pharmacological Properties of Plecanatide (SP-304) and the Human Hormone Uroguanylin: 1340

Genomics strategies for antifungal drug discovery--from gene discovery to compound screening

Tu1211 IW-9179, a Phosphopeptide Designed to Target the Upper Gastrointestinal Tract, Is More Potent at Acidic pH and Is Rapidly Metabolized In Vitro in Rodent Intestinal Fluid

956 IW-9179, a Potent Guanylate Cyclase-C (GC-C) Agonist, Improves Gastric Emptying In Vivo and Modulates Gastric Vagal Afferent Mechanosensitivity In Vitro

The use of direct cDNA selection to rapidly and effectively identify genes in the fungus Aspergillus fumigatus

Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3'-end formation in yeast

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