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CSF1R-dependent macrophages control postnatal somatic growth and organ maturation

PLoS genetics, 2021-06, Vol.17 (6), p.e1009605-e1009605

2021

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Analysis of homozygous and heterozygous Csf1r knockout in the rat as a model for understanding microglial function in brain development and the impacts of human CSF1R mutations

Neurobiology of disease, 2021-04, Vol.151, p.105268-105268, Article 105268

2021

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Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis

Nature communications, 2024-05, Vol.15 (1), p.4527-12, Article 4527

2024

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Liver and pancreatic-targeted interleukin-22 as a therapeutic for metabolic dysfunction-associated steatohepatitis

Nature communications, 2024-05, Vol.15 (1), p.4528-13, Article 4528

2024

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Editorial: Adipose Tissue in Obesity and Metabolic Disease

Frontiers in physiology, 2022-04, Vol.13, p.898861-898861

2022

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Therapeutic potential of macrophage colony-stimulating factor in chronic liver disease

Disease models & mechanisms, 2022-04, Vol.15 (4)

2022

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Pre-Diabetes Increases Tuberculosis Disease Severity, While High Body Fat Without Impaired Glucose Tolerance Is Protective

Frontiers in cellular and infection microbiology, 2021-07, Vol.11, p.691823-691823

2021

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Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction

Islets, 2018-01, Vol.10 (1), p.10-24

2018

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Macrophage deficiency in CSF1R-knockout rat embryos does not compromise placental or embryo development

Journal of leukocyte biology, 2023-10, Vol.114 (5), p.421-433

2023

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89: BUILDING A CASE FOR LIVER AND PANCREAS TARGETED INTERLEUKIN-22 THERAPY FOR USE IN NON-ALCOHOLIC FATTY LIVER DISEASE

Gastroenterology (New York, N.Y. 1943), 2022-05, Vol.162 (7), p.S-14-S-14

2022

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Evolution of the magic bullet: Single chain antibody fragments for the targeted delivery of immunomodulatory proteins

Experimental biology and medicine (Maywood, N.J.), 2018-01, Vol.243 (2), p.166-183

2018

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Non-classical monocytes scavenge the growth factor CSF1 from endothelial cells in the peripheral vascular tree to ensure survival and homeostasis

Immunity (Cambridge, Mass.), 2024-09, Vol.57 (9), p.2108-2121.e6

2024

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Relative contributions of osteal macrophages and osteoclasts to postnatal bone development in CSF1R-deficient rats and phenotype rescue following wild-type bone marrow cell transfer

Journal of leukocyte biology, 2024-10, Vol.116 (4), p.753-765

2024

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CSF1R as a Therapeutic Target in Bone Diseases: Obvious but Not so Simple

Current osteoporosis reports, 2022-12, Vol.20 (6), p.516-531

2022

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Analysis of the impact of CSF‐1 administration in adult rats using a novel Csf1r‐mApple reporter gene

Journal of leukocyte biology, 2020-02, Vol.107 (2), p.221-235

2020

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The Mononuclear Phagocyte System of the Rat

The Journal of immunology (1950), 2021-05, Vol.206 (10), p.2251-2263

2021

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119-LB: Targeted IL-22 Improves Glucose Tolerance and Reduces Hepatic Steatosis and Hepatic Fibrosis in Murine Models of Diabetes and Liver Disease

Diabetes (New York, N.Y.), 2022-06, Vol.71 (Supplement_1)

2022

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Building a case for pancreas and liver targeted intereukin-22 therapy in fatty liver disease

Journal of hepatology, 2022-07, Vol.77, p.S190-S191

2022

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Pancreatic Interleukin-22 Receptor Signaling is Critical in Maintaining Beta-Cell Insulin Production and is Hepatoprotective

The Journal of immunology (1950), 2022-05, Vol.208 (1_Supplement), p.46-46.08

2022

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Intraperitoneal transfer of wild‐type bone marrow repopulates tissue macrophages in the Csf1r knockout rat without contributing to monocytopoiesis

European journal of immunology, 2023-08, Vol.53 (8), p.e2250312-n/a

2023

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Fibrillin-1 and asprosin, novel players in metabolic syndrome

Molecular genetics and metabolism, 2023-01, Vol.138 (1), p.106979-106979, Article 106979

2023

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Characterisation of the adiponectin receptors: Differential cell-surface expression and temporal signalling profiles of AdipoR1 and AdipoR2 are regulated by the non-conserved N-terminal trunks

Molecular and cellular endocrinology, 2015-07, Vol.409, p.121-129

2015

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A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling

Development (Cambridge), 2022-04, Vol.149 (8)

2022

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Serum CC-Chemokine Ligand 2 Is Associated with Visceral Adiposity but Not Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease

Digestive diseases (Basel), 2023-05, Vol.41 (3), p.439-446

2023

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Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic lipid and carbohydrate metabolism

American journal of physiology: endocrinology and metabolism, 2024-02, Vol.326 (2), p.E149-E165

2024

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CSF1R-dependent macrophages control postnatal somatic growth and organ maturation

Analysis of homozygous and heterozygous Csf1r knockout in the rat as a model for understanding microglial function in brain development and the impacts of human CSF1R mutations

Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis

Liver and pancreatic-targeted interleukin-22 as a therapeutic for metabolic dysfunction-associated steatohepatitis

Editorial: Adipose Tissue in Obesity and Metabolic Disease

Therapeutic potential of macrophage colony-stimulating factor in chronic liver disease

Pre-Diabetes Increases Tuberculosis Disease Severity, While High Body Fat Without Impaired Glucose Tolerance Is Protective

Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction

Macrophage deficiency in CSF1R-knockout rat embryos does not compromise placental or embryo development

89: BUILDING A CASE FOR LIVER AND PANCREAS TARGETED INTERLEUKIN-22 THERAPY FOR USE IN NON-ALCOHOLIC FATTY LIVER DISEASE

Evolution of the magic bullet: Single chain antibody fragments for the targeted delivery of immunomodulatory proteins

Non-classical monocytes scavenge the growth factor CSF1 from endothelial cells in the peripheral vascular tree to ensure survival and homeostasis

Relative contributions of osteal macrophages and osteoclasts to postnatal bone development in CSF1R-deficient rats and phenotype rescue following wild-type bone marrow cell transfer

CSF1R as a Therapeutic Target in Bone Diseases: Obvious but Not so Simple

Analysis of the impact of CSF‐1 administration in adult rats using a novel Csf1r‐mApple reporter gene

The Mononuclear Phagocyte System of the Rat

119-LB: Targeted IL-22 Improves Glucose Tolerance and Reduces Hepatic Steatosis and Hepatic Fibrosis in Murine Models of Diabetes and Liver Disease

Building a case for pancreas and liver targeted intereukin-22 therapy in fatty liver disease

Pancreatic Interleukin-22 Receptor Signaling is Critical in Maintaining Beta-Cell Insulin Production and is Hepatoprotective

Intraperitoneal transfer of wild‐type bone marrow repopulates tissue macrophages in the Csf1r knockout rat without contributing to monocytopoiesis

Fibrillin-1 and asprosin, novel players in metabolic syndrome

Characterisation of the adiponectin receptors: Differential cell-surface expression and temporal signalling profiles of AdipoR1 and AdipoR2 are regulated by the non-conserved N-terminal trunks

A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling

Serum CC-Chemokine Ligand 2 Is Associated with Visceral Adiposity but Not Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease

Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic lipid and carbohydrate metabolism

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