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Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design

The Journal of biological chemistry, 2009-09, Vol.284 (38), p.25697-25703

2009

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In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi

PLoS neglected tropical diseases, 2010-09, Vol.4 (9), p.e825

2010

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Crystal Structures of TbCatB and rhodesain, potential chemotherapeutic targets and major cysteine proteases of Trypanosoma brucei

PLoS neglected tropical diseases, 2010-06, Vol.4 (6), p.e701-e701

2010

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Hemoglobin cleavage site-specificity of the Plasmodium falciparum cysteine proteases falcipain-2 and falcipain-3

PloS one, 2009-04, Vol.4 (4), p.e5156-e5156

2009

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Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome

Acta crystallographica. Section F, Structural biology communications, 2015-08, Vol.71 (8), p.981-985

2015

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Structures of Falcipain-2 and Falcipain-3 Bound to Small Molecule Inhibitors: Implications for Substrate Specificity

Journal of medicinal chemistry, 2009-02, Vol.52 (3), p.852-857

2009

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The Science and Art of Clinical Genetic Variant Classification and Its Impact on Test Accuracy

Annual review of genomics and human genetics, 2021-01, Vol.22 (1), p.285-307

2021

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Nonpeptidic Tetrafluorophenoxymethyl Ketone Cruzain Inhibitors as Promising New Leads for Chagas Disease Chemotherapy

Journal of medicinal chemistry, 2010-02, Vol.53 (4), p.1763-1773

2010

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Crystallographic and NMR Analyses of UvsW and UvsW.1 from Bacteriophage T4

The Journal of biological chemistry, 2007-11, Vol.282 (47), p.34392-34400

2007

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Structural Studies of Pterin-Based Inhibitors of Dihydropteroate Synthase

Journal of medicinal chemistry, 2010-01, Vol.53 (1), p.166-177

2010

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Comparison of locus-specific databases for BRCA1 and BRCA2 variants reveals disparity in variant classification within and among databases

Journal of community genetics, 2015-10, Vol.6 (4), p.351-359

2015

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A Novel Entamoeba histolytica Cysteine Proteinase, EhCP4, Is Key for Invasive Amebiasis and a Therapeutic Target

The Journal of biological chemistry, 2010-06, Vol.285 (24), p.18516-18527

2010

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Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases

Bioorganic & medicinal chemistry letters, 2009-11, Vol.19 (21), p.6218-6221

2009

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Assessment of in silico protein sequence analysis in the clinical classification of variants in cancer risk genes

Journal of community genetics, 2017-04, Vol.8 (2), p.87-95

2017

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Insights into ssDNA recognition by the OB fold from a structural and thermodynamic study of Sulfolobus SSB protein

The EMBO journal, 2003-06, Vol.22 (11), p.2561-2570

2003

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Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome

Acta crystallographica. Section F, Structural biology communications, 2015-07, Vol.71 (Pt 8)

2015

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Variation on a theme of SDR. dTDP-6-deoxy-L- lyxo-4-hexulose reductase (RmlD) shows a new Mg2+-dependent dimerization mode

Structure (London), 2002-06, Vol.10 (6), p.773

2002

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Variation on a Theme of SDR

Structure (London), 2002-06, Vol.10 (6), p.773-786

2002

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Variation on a Theme of SDR: dTDP-6-Deoxy-L- lyxo-4-Hexulose Reductase (RmlD) Shows a New Mg 2+-Dependent Dimerization Mode

Structure (London), 2002, Vol.10 (6), p.773-786

2002

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Overexpression, purification, crystallization and data collection of a single-stranded DNA-binding protein from Sulfolobus solfataricus

Acta crystallographica. Section D, Biological crystallography., 2001-09, Vol.57 (9), p.1290-1292

2001

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Protection against SARS-CoV-2 after Covid-19 Vaccination and Previous Infection

The New England journal of medicine, 2022-03, Vol.386 (13), p.1207-1220

2022

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Cutting Edge: Mast Cells Express IL-17A in Rheumatoid Arthritis Synovium

The Journal of immunology (1950), 2010-04, Vol.184 (7), p.3336-3340

2010

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Intravenous Iron in Patients Undergoing Maintenance Hemodialysis

The New England journal of medicine, 2019-01, Vol.380 (5), p.447-458

2019

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Mineralogy, Chemistry, and Fluid-Aided Evolution of the Pea Ridge Fe Oxide-(Y + REE) Deposit, Southeast Missouri, USA

Economic geology and the bulletin of the Society of Economic Geologists, 2016-12, Vol.111 (8), p.1963-1984

2016

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Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure

The New England journal of medicine, 2020-10, Vol.383 (15), p.1413-1424

2020

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Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design

In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi

Crystal Structures of TbCatB and rhodesain, potential chemotherapeutic targets and major cysteine proteases of Trypanosoma brucei

Hemoglobin cleavage site-specificity of the Plasmodium falciparum cysteine proteases falcipain-2 and falcipain-3

Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome

Structures of Falcipain-2 and Falcipain-3 Bound to Small Molecule Inhibitors: Implications for Substrate Specificity

The Science and Art of Clinical Genetic Variant Classification and Its Impact on Test Accuracy

Nonpeptidic Tetrafluorophenoxymethyl Ketone Cruzain Inhibitors as Promising New Leads for Chagas Disease Chemotherapy

Crystallographic and NMR Analyses of UvsW and UvsW.1 from Bacteriophage T4

Structural Studies of Pterin-Based Inhibitors of Dihydropteroate Synthase

Comparison of locus-specific databases for BRCA1 and BRCA2 variants reveals disparity in variant classification within and among databases

A Novel Entamoeba histolytica Cysteine Proteinase, EhCP4, Is Key for Invasive Amebiasis and a Therapeutic Target

Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases

Assessment of in silico protein sequence analysis in the clinical classification of variants in cancer risk genes

Insights into ssDNA recognition by the OB fold from a structural and thermodynamic study of Sulfolobus SSB protein

Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome

Variation on a theme of SDR. dTDP-6-deoxy-L- lyxo-4-hexulose reductase (RmlD) shows a new Mg2+-dependent dimerization mode

Variation on a Theme of SDR

Variation on a Theme of SDR: dTDP-6-Deoxy-L- lyxo-4-Hexulose Reductase (RmlD) Shows a New Mg 2+-Dependent Dimerization Mode

Overexpression, purification, crystallization and data collection of a single-stranded DNA-binding protein from Sulfolobus solfataricus

Protection against SARS-CoV-2 after Covid-19 Vaccination and Previous Infection

Cutting Edge: Mast Cells Express IL-17A in Rheumatoid Arthritis Synovium

Intravenous Iron in Patients Undergoing Maintenance Hemodialysis

Mineralogy, Chemistry, and Fluid-Aided Evolution of the Pea Ridge Fe Oxide-(Y + REE) Deposit, Southeast Missouri, USA

Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure

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