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Dietary Indole-3-Carbinol Activates AhR in the Gut, Alters Th17-Microbe Interactions, and Exacerbates Insulitis in NOD Mice

Frontiers in immunology, 2021-01, Vol.11, p.606441

2021

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The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells

PloS one, 2012-07, Vol.7 (7), p.e40926-e40926

2012

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TCDD: An Environmental Immunotoxicant Reveals a Novel Pathway of Immunoregulation—A 30-Year Odyssey

Toxicologic pathology, 2012-02, Vol.40 (2), p.138-142

Kerkvliet, Nancy I.

2012

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Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands

Journal of medicinal chemistry, 2009-09, Vol.52 (18), p.5635-5641

2009

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Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2-responding CD4 + T cells

Frontiers in immunology, 2023-11, Vol.14, p.1193535-1193535

2023

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The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

PloS one, 2010-10, Vol.5 (10), p.e13128

2010

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Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease

PloS one, 2014-02, Vol.9 (2), p.e88726

2014

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TCDD, FICZ, and Other High Affinity AhR Ligands Dose-Dependently Determine the Fate of CD4+ T Cell Differentiation

Toxicological sciences, 2018-02, Vol.161 (2), p.310-320

2018

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Dioxin and immune regulation: emerging role of aryl hydrocarbon receptor in the generation of regulatory T cells

Annals of the New York Academy of Sciences, 2010-01, Vol.1183 (1), p.25-37

2010

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Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells

Biology (Basel, Switzerland), 2017-12, Vol.6 (4), p.41

2017

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A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain

Biology (Basel, Switzerland), 2014-10, Vol.3 (4), p.645-669

2014

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Immune Cell Phenotyping Using Flow Cytometry

Current Protocols in Toxicology, 2015-11, Vol.66 (1), p.18.8.1-18.8.34

2015

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Aryl Hydrocarbon Receptor-Mediated Perturbations in Gene Expression during Early Stages of CD4(+) T-cell Differentiation

Frontiers in immunology, 2012-01, Vol.3, p.223

2012

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Discovery and Mechanistic Characterization of a Select Modulator of AhR-regulated Transcription (SMAhRT) with Anti-cancer Effects

Apoptosis (London), 2021-06, Vol.26 (5-6), p.307-322

2021

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Aryl Hydrocarbon Receptor-Deficient Mice Generate Normal Immune Responses to Model Antigens and Are Resistant to TCDD-Induced Immune Suppression

Toxicology and applied pharmacology, 2001-03, Vol.171 (3), p.157-164

2001

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Dioxin and immune regulation

Annals of the New York Academy of Sciences, 2010-01, Vol.1183 (1), p.25-37

2010

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Toxicity Testing in the 21st Century: A Vision and a Strategy

Journal of toxicology and environmental health. Part B, Critical reviews, 2010-02, Vol.13 (2-4), p.51-138

2010

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11-Cl-BBQ, a select modulator of AhR-regulated transcription, suppresses lung cancer cell growth via activation of p53 and p27 Kip1

The FEBS journal, 2023-04, Vol.290 (8), p.2064-2084

2023

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11‐Cl‐BBQ, a select modulator of AhR‐regulated transcription, suppresses lung cancer cell growth via activation of p53 and p27Kip1

The FEBS journal, 2023-04, Vol.290 (8), p.2064-2084

2023

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Recent advances in understanding the mechanisms of TCDD immunotoxicity

International Immunopharmacology, 2002-02, Vol.2 (2), p.277-291

Kerkvliet, Nancy I

2002

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Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice

The Journal of immunology (1950), 2016-01, Vol.196 (1), p.264-273

2016

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Recent advances in understanding the mechanisms of TCDD immunotoxicity

International immunopharmacology, 2002-02, Vol.2 (2-3), p.277-291

Kerkvliet, Nancy I

2002

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Arsenic exposure and prevalence of the varicella zoster virus in the United States: NHANES (2003-2004 and 2009-2010)

Environmental health perspectives, 2015-06, Vol.123 (6), p.590-590

2015

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Suppression of acute graft-versus-host response by TCDD is independent of the CTLA-4-IFN-γ-IDO pathway

Toxicological sciences, 2013-09, Vol.135 (1), p.81-90

2013

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Cutting Edge: Activation of the Aryl Hydrocarbon Receptor by 2,3,7,8-Tetrachlorodibenzo-p-dioxin Generates a Population of CD4+CD25+ Cells with Characteristics of Regulatory T Cells

The Journal of immunology (1950), 2005-10, Vol.175 (7), p.4184-4188

2005

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Dietary Indole-3-Carbinol Activates AhR in the Gut, Alters Th17-Microbe Interactions, and Exacerbates Insulitis in NOD Mice

The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells

TCDD: An Environmental Immunotoxicant Reveals a Novel Pathway of Immunoregulation—A 30-Year Odyssey

Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands

Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2-responding CD4 + T cells

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease

TCDD, FICZ, and Other High Affinity AhR Ligands Dose-Dependently Determine the Fate of CD4+ T Cell Differentiation

Dioxin and immune regulation: emerging role of aryl hydrocarbon receptor in the generation of regulatory T cells

Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells

A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain

Immune Cell Phenotyping Using Flow Cytometry

Aryl Hydrocarbon Receptor-Mediated Perturbations in Gene Expression during Early Stages of CD4(+) T-cell Differentiation

Discovery and Mechanistic Characterization of a Select Modulator of AhR-regulated Transcription (SMAhRT) with Anti-cancer Effects

Aryl Hydrocarbon Receptor-Deficient Mice Generate Normal Immune Responses to Model Antigens and Are Resistant to TCDD-Induced Immune Suppression

Dioxin and immune regulation

Toxicity Testing in the 21st Century: A Vision and a Strategy

11-Cl-BBQ, a select modulator of AhR-regulated transcription, suppresses lung cancer cell growth via activation of p53 and p27 Kip1

11‐Cl‐BBQ, a select modulator of AhR‐regulated transcription, suppresses lung cancer cell growth via activation of p53 and p27Kip1

Recent advances in understanding the mechanisms of TCDD immunotoxicity

Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice

Recent advances in understanding the mechanisms of TCDD immunotoxicity

Arsenic exposure and prevalence of the varicella zoster virus in the United States: NHANES (2003-2004 and 2009-2010)

Suppression of acute graft-versus-host response by TCDD is independent of the CTLA-4-IFN-γ-IDO pathway

Cutting Edge: Activation of the Aryl Hydrocarbon Receptor by 2,3,7,8-Tetrachlorodibenzo-p-dioxin Generates a Population of CD4+CD25+ Cells with Characteristics of Regulatory T Cells

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