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AHR-mediated immunomodulation: The role of altered gene transcription

Biochemical pharmacology, 2009-02, Vol.77 (4), p.746-760

Kerkvliet, Nancy I.

2009

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Discovery and Mechanistic Characterization of a Select Modulator of AhR-regulated Transcription (SMAhRT) with Anti-cancer Effects

Apoptosis (London), 2021-06, Vol.26 (5-6), p.307-322

2021

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Dietary Indole-3-Carbinol Activates AhR in the Gut, Alters Th17-Microbe Interactions, and Exacerbates Insulitis in NOD Mice

Frontiers in immunology, 2021-01, Vol.11, p.606441

2021

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TCDD, FICZ, and Other High Affinity AhR Ligands Dose-Dependently Determine the Fate of CD4+ T Cell Differentiation

Toxicological sciences, 2018-02, Vol.161 (2), p.310-320

2018

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The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells

PloS one, 2012-07, Vol.7 (7), p.e40926-e40926

2012

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Dioxin and immune regulation: emerging role of aryl hydrocarbon receptor in the generation of regulatory T cells

Annals of the New York Academy of Sciences, 2010-01, Vol.1183 (1), p.25-37

2010

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Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands

Journal of medicinal chemistry, 2009-09, Vol.52 (18), p.5635-5641

2009

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The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

PloS one, 2010-10, Vol.5 (10), p.e13128

2010

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TCDD: An Environmental Immunotoxicant Reveals a Novel Pathway of Immunoregulation—A 30-Year Odyssey

Toxicologic pathology, 2012-02, Vol.40 (2), p.138-142

Kerkvliet, Nancy I.

2012

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Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease

PloS one, 2014-02, Vol.9 (2), p.e88726

2014

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Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2-responding CD4 + T cells

Frontiers in immunology, 2023-11, Vol.14, p.1193535-1193535

2023

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Toxicity Testing in the 21st Century: A Vision and a Strategy

Journal of toxicology and environmental health. Part B, Critical reviews, 2010-02, Vol.13 (2-4), p.51-138

2010

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11-Cl-BBQ, a select modulator of AhR-regulated transcription, suppresses lung cancer cell growth via activation of p53 and p27 Kip1

The FEBS journal, 2023-04, Vol.290 (8), p.2064-2084

2023

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11‐Cl‐BBQ, a select modulator of AhR‐regulated transcription, suppresses lung cancer cell growth via activation of p53 and p27Kip1

The FEBS journal, 2023-04, Vol.290 (8), p.2064-2084

2023

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AhR activation increases IL‐2 production by alloreactive CD4+ T cells initiating the differentiation of mucosal‐homing Tim3+Lag3+ Tr1 cells

European journal of immunology, 2017-11, Vol.47 (11), p.1989-2001

2017

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A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain

Biology (Basel, Switzerland), 2014-10, Vol.3 (4), p.645-669

2014

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Recent advances in understanding the mechanisms of TCDD immunotoxicity

International immunopharmacology, 2002-02, Vol.2 (2-3), p.277-291

Kerkvliet, Nancy I

2002

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Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice

The Journal of immunology (1950), 2016-01, Vol.196 (1), p.264-273

2016

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Arsenic exposure and prevalence of the varicella zoster virus in the United States: NHANES (2003-2004 and 2009-2010)

Environmental health perspectives, 2015-06, Vol.123 (6), p.590-590

2015

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Cutting Edge: Activation of the Aryl Hydrocarbon Receptor by 2,3,7,8-Tetrachlorodibenzo-p-dioxin Generates a Population of CD4+CD25+ Cells with Characteristics of Regulatory T Cells

The Journal of immunology (1950), 2005-10, Vol.175 (7), p.4184-4188

2005

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Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells

Biology (Basel, Switzerland), 2017-12, Vol.6 (4), p.41

2017

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Suppression of acute graft-versus-host response by TCDD is independent of the CTLA-4-IFN-γ-IDO pathway

Toxicological sciences, 2013-09, Vol.135 (1), p.81-90

2013

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Functional Characterization and Gene Expression Analysis of CD4+CD25+ Regulatory T Cells Generated in Mice Treated with 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

The Journal of immunology (1950), 2008-08, Vol.181 (4), p.2382-2391

2008

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In vivo contaminant partitioning to silicone implants: Implications for use in biomonitoring and body burden

Environment international, 2015-12, Vol.85, p.182-188

2015

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The aryl hydrocarbon receptor is required for induction of p21cip1/waf1 expression and growth inhibition by SU5416 in hepatoma cells

Oncotarget, 2017-04, Vol.8 (15), p.25211-25225

2017

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AHR-mediated immunomodulation: The role of altered gene transcription

Discovery and Mechanistic Characterization of a Select Modulator of AhR-regulated Transcription (SMAhRT) with Anti-cancer Effects

Dietary Indole-3-Carbinol Activates AhR in the Gut, Alters Th17-Microbe Interactions, and Exacerbates Insulitis in NOD Mice

TCDD, FICZ, and Other High Affinity AhR Ligands Dose-Dependently Determine the Fate of CD4+ T Cell Differentiation

The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells

Dioxin and immune regulation: emerging role of aryl hydrocarbon receptor in the generation of regulatory T cells

Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

TCDD: An Environmental Immunotoxicant Reveals a Novel Pathway of Immunoregulation—A 30-Year Odyssey

Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease

Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2-responding CD4 + T cells

Toxicity Testing in the 21st Century: A Vision and a Strategy

11-Cl-BBQ, a select modulator of AhR-regulated transcription, suppresses lung cancer cell growth via activation of p53 and p27 Kip1

11‐Cl‐BBQ, a select modulator of AhR‐regulated transcription, suppresses lung cancer cell growth via activation of p53 and p27Kip1

AhR activation increases IL‐2 production by alloreactive CD4+ T cells initiating the differentiation of mucosal‐homing Tim3+Lag3+ Tr1 cells

A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain

Recent advances in understanding the mechanisms of TCDD immunotoxicity

Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice

Arsenic exposure and prevalence of the varicella zoster virus in the United States: NHANES (2003-2004 and 2009-2010)

Cutting Edge: Activation of the Aryl Hydrocarbon Receptor by 2,3,7,8-Tetrachlorodibenzo-p-dioxin Generates a Population of CD4+CD25+ Cells with Characteristics of Regulatory T Cells

Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells

Suppression of acute graft-versus-host response by TCDD is independent of the CTLA-4-IFN-γ-IDO pathway

Functional Characterization and Gene Expression Analysis of CD4+CD25+ Regulatory T Cells Generated in Mice Treated with 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

In vivo contaminant partitioning to silicone implants: Implications for use in biomonitoring and body burden

The aryl hydrocarbon receptor is required for induction of p21cip1/waf1 expression and growth inhibition by SU5416 in hepatoma cells

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