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Structure-guided design of an Hsp90β N-terminal isoform-selective inhibitor

Nature communications, 2018-01, Vol.9 (1), p.425-7, Article 425

2018

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Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding

Journal of medicinal chemistry, 2018-04, Vol.61 (7), p.2793-2805

2018

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Classics in Chemical Neuroscience: Baclofen

ACS chemical neuroscience, 2020-06, Vol.11 (12), p.1740-1755

2020

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Back to the Medicinal Chemistry Future

Journal of medicinal chemistry, 2021-11, Vol.64 (21), p.15515-15518

2021

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The Development of Hsp90β-Selective Inhibitors to Overcome Detriments Associated with pan-Hsp90 Inhibition

Journal of medicinal chemistry, 2021-02, Vol.64 (3), p.1545-1557

2021

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Structure‐Based Design, Synthesis, and Biological Evaluation of Hsp90β‐Selective Inhibitors

Chemistry : a European journal, 2021-10, Vol.27 (59), p.14747-14764

2021

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VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels

Molecular pharmacology, 2022-05, Vol.101 (5), p.357-370

2022

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Discovery and optimization of a novel CNS penetrant series of mGlu4 PAMs based on a 1,4-thiazepane core with in vivo efficacy in a preclinical Parkinsonian model

Bioorganic & medicinal chemistry letters, 2021-04, Vol.37, p.127838-127838, Article 127838

2021

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Synthesis and Biological Evaluation of Stilbene Analogues as Hsp90 C‐Terminal Inhibitors

ChemMedChem, 2017-12, Vol.12 (24), p.2022-2029

2017

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Cover Feature: Synthesis and Biological Evaluation of Stilbene Analogues as Hsp90 C‐Terminal Inhibitors (ChemMedChem 24/2017)

ChemMedChem, 2017-12, Vol.12 (24), p.2015-2015

2017

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Discovery of a Novel, Selective Inhibitor of the Kir4.1/5.1Heterotetramer, Development of a Novel mGlu4 PAM Chemotype, and Progress Towards the Total Synthesis of Thiocladospolide A

Kent, Caitlin N

2021

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Discovery and optimization of a novel CNS penetrant series of mGlu 4 PAMs based on a 1,4-thiazepane core with in vivo efficacy in a preclinical Parkinsonian model

Bioorganic & medicinal chemistry letters, 2021-04, Vol.37, p.127838

2021

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A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma

Cell, 2024-01, Vol.187 (2), p.464-480.e10

2024

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Does the Use of Clean or Sterile Dressing Technique Affect the Incidence of Wound Infection?

Journal of wound, ostomy, and continence nursing, 2018-05, Vol.45 (3), p.265-269

2018

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Comparison of FilmArray and Quantitative Real-Time Reverse Transcriptase PCR for Detection of Zaire Ebolavirus from Contrived and Clinical Specimens

Journal of clinical microbiology, 2015-09, Vol.53 (9), p.2956-2960

2015

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Variation of the aryl substituent on the piperazine ring within the 4-(piperazin-1-yl)-2,6-di(pyrrolidin-1-yl)pyrimidine scaffold unveils potent, non-competitive inhibitors of the inflammatory caspases

Bioorganic & medicinal chemistry letters, 2016-11, Vol.26 (22), p.5476-5480

2016

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Federal Programs in Climate Change and Health Research

Climate Change and Global Public Health, 2021, p.483-504

2021

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Structure-guided design of an Hsp90β N-terminal isoform-selective inhibitor

Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding

Classics in Chemical Neuroscience: Baclofen

Back to the Medicinal Chemistry Future

The Development of Hsp90β-Selective Inhibitors to Overcome Detriments Associated with pan-Hsp90 Inhibition

Structure‐Based Design, Synthesis, and Biological Evaluation of Hsp90β‐Selective Inhibitors

VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels

Discovery and optimization of a novel CNS penetrant series of mGlu4 PAMs based on a 1,4-thiazepane core with in vivo efficacy in a preclinical Parkinsonian model

Synthesis and Biological Evaluation of Stilbene Analogues as Hsp90 C‐Terminal Inhibitors

Cover Feature: Synthesis and Biological Evaluation of Stilbene Analogues as Hsp90 C‐Terminal Inhibitors (ChemMedChem 24/2017)

Discovery of a Novel, Selective Inhibitor of the Kir4.1/5.1Heterotetramer, Development of a Novel mGlu4 PAM Chemotype, and Progress Towards the Total Synthesis of Thiocladospolide A

Discovery and optimization of a novel CNS penetrant series of mGlu 4 PAMs based on a 1,4-thiazepane core with in vivo efficacy in a preclinical Parkinsonian model

A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma

Does the Use of Clean or Sterile Dressing Technique Affect the Incidence of Wound Infection?

Comparison of FilmArray and Quantitative Real-Time Reverse Transcriptase PCR for Detection of Zaire Ebolavirus from Contrived and Clinical Specimens

Variation of the aryl substituent on the piperazine ring within the 4-(piperazin-1-yl)-2,6-di(pyrrolidin-1-yl)pyrimidine scaffold unveils potent, non-competitive inhibitors of the inflammatory caspases

Federal Programs in Climate Change and Health Research

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