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Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport

PLoS genetics, 2016-12, Vol.12 (12), p.e1006469-e1006469

2016

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Ciliary Rab28 and the BBSome negatively regulate extracellular vesicle shedding

eLife, 2020-02, Vol.9

2020

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Evaluation of the Therapeutic Potential of Histone Deacetylase 6 Inhibitors for Primary and Metastatic Uveal Melanoma

International journal of molecular sciences, 2022-08, Vol.23 (16), p.9378

2022

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Gene therapy for RAB28: What can we learn from zebrafish?

Vision research (Oxford), 2023-09, Vol.210, p.108270-108270, Article 108270

2023

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Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib

Scientific reports, 2020-07, Vol.10 (1), p.12105-12105, Article 12105

2020

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Early safety assessment of human oculotoxic drugs using the zebrafish visualmotor response

Journal of pharmacological and toxicological methods, 2014-01, Vol.69 (1), p.1-8

2014

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Regulation of the rhythmic diversity of daily photoreceptor outer segment phagocytosis in vivo

The FASEB journal, 2022-10, Vol.36 (10), p.e22556-n/a

2022

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Combining 1,4-dihydroxy quininib with Bevacizumab/FOLFOX alters angiogenic and inflammatory secretions in ex vivo colorectal tumors

BMC cancer, 2020-10, Vol.20 (1), p.952-14, Article 952

2020

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A sustained release formulation of novel quininib-hyaluronan microneedles inhibits angiogenesis and retinal vascular permeability in vivo

Journal of controlled release, 2016-07, Vol.233, p.198-207

2016

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Selective inhibition of retinal angiogenesis by targeting PI3 kinase

PloS one, 2009-11, Vol.4 (11), p.e7867-e7867

2009

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Non-photopic and photopic visual cycles differentially regulate immediate, early, and late phases of cone photoreceptor-mediated vision

The Journal of biological chemistry, 2020-05, Vol.295 (19), p.6482-6497

2020

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Neuroprotective Nanoparticles Targeting the Retina: A Polymeric Platform for Ocular Drug Delivery Applications

Pharmaceutics, 2023-03, Vol.15 (4), p.1096

2023

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Pharmacological restoration of visual function in a zebrafish model of von-Hippel Lindau disease

Developmental biology, 2020-01, Vol.457 (2), p.226-234

2020

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Genes and signaling networks regulated during zebrafish optic vesicle morphogenesis

BMC genomics, 2014-09, Vol.15 (1), p.825-825, Article 825

2014

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Brain-Derived Neurotrophic Factor as a Treatment Option for Retinal Degeneration

Advances in experimental medicine and biology, 2018, Vol.1074, p.465-471

2018

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The Role of Mitochondria in Optic Atrophy With Autosomal Inheritance

Frontiers in neuroscience, 2021-11, Vol.15, p.784987

2021

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Dawn and dusk peaks of outer segment phagocytosis, and visual cycle function require Rab28

The FASEB journal, 2022-05, Vol.36 (5), p.e22309-n/a

2022

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Pyrazinib (P3), [(E)-2-(2-Pyrazin-2-yl-vinyl)-phenol], a small molecule pyrazine compound enhances radiosensitivity in oesophageal adenocarcinoma

Cancer letters, 2019-04, Vol.447, p.115-129

2019

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Uveal Melanoma Cell Line Proliferation Is Inhibited by Ricolinostat, a Histone Deacetylase Inhibitor

Cancers, 2022-02, Vol.14 (3), p.782

2022

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Targeting the PI3K/Akt/mTOR pathway in ocular neovascularization

Advances in experimental medicine and biology, 2014, Vol.801, p.805

2014

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Histone Deacetylase: Therapeutic Targets in Retinal Degeneration

Advances in experimental medicine and biology, 2016-01, Vol.854, p.455-461

2016

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A Quininib Analogue and Cysteinyl Leukotriene Receptor Antagonist Inhibits Vascular Endothelial Growth Factor (VEGF)-independent Angiogenesis and Exerts an Additive Antiangiogenic Response with Bevacizumab

The Journal of biological chemistry, 2017-03, Vol.292 (9), p.3552-3567

2017

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A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model

Scientific reports, 2017-09, Vol.7 (1), p.11320-18, Article 11320

2017

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Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport

Ciliary Rab28 and the BBSome negatively regulate extracellular vesicle shedding

Evaluation of the Therapeutic Potential of Histone Deacetylase 6 Inhibitors for Primary and Metastatic Uveal Melanoma

Gene therapy for RAB28: What can we learn from zebrafish?

Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib

Early safety assessment of human oculotoxic drugs using the zebrafish visualmotor response

Regulation of the rhythmic diversity of daily photoreceptor outer segment phagocytosis in vivo

Combining 1,4-dihydroxy quininib with Bevacizumab/FOLFOX alters angiogenic and inflammatory secretions in ex vivo colorectal tumors

A sustained release formulation of novel quininib-hyaluronan microneedles inhibits angiogenesis and retinal vascular permeability in vivo

Selective inhibition of retinal angiogenesis by targeting PI3 kinase

Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro and In Vivo Efficacy

High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma Cells

Non-photopic and photopic visual cycles differentially regulate immediate, early, and late phases of cone photoreceptor-mediated vision

Neuroprotective Nanoparticles Targeting the Retina: A Polymeric Platform for Ocular Drug Delivery Applications

Pharmacological restoration of visual function in a zebrafish model of von-Hippel Lindau disease

Genes and signaling networks regulated during zebrafish optic vesicle morphogenesis

Brain-Derived Neurotrophic Factor as a Treatment Option for Retinal Degeneration

The Role of Mitochondria in Optic Atrophy With Autosomal Inheritance

Dawn and dusk peaks of outer segment phagocytosis, and visual cycle function require Rab28

Pyrazinib (P3), [(E)-2-(2-Pyrazin-2-yl-vinyl)-phenol], a small molecule pyrazine compound enhances radiosensitivity in oesophageal adenocarcinoma

Uveal Melanoma Cell Line Proliferation Is Inhibited by Ricolinostat, a Histone Deacetylase Inhibitor

Targeting the PI3K/Akt/mTOR pathway in ocular neovascularization

Histone Deacetylase: Therapeutic Targets in Retinal Degeneration

A Quininib Analogue and Cysteinyl Leukotriene Receptor Antagonist Inhibits Vascular Endothelial Growth Factor (VEGF)-independent Angiogenesis and Exerts an Additive Antiangiogenic Response with Bevacizumab

A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model

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