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Animal models of pulmonary hypertension: Getting to the heart of the problem

British journal of pharmacology, 2022-03, Vol.179 (5), p.811-837

2022

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Inflammasomes: a novel therapeutic target in pulmonary hypertension?

British journal of pharmacology, 2019-06, Vol.176 (12), p.1880-1896

2019

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Simultaneous targeting of oxidative stress and fibrosis reverses cardiomyopathy‐induced ventricular remodelling and dysfunction

British journal of pharmacology, 2021-06, Vol.178 (12), p.2424-2442

2021

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Cardioprotective actions of nitroxyl donor Angeli's salt are preserved in the diabetic heart and vasculature in the face of nitric oxide resistance

British journal of pharmacology, 2022-08, Vol.179 (16), p.4117-4135

2022

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Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension

Cardiovascular research, 2019-03, Vol.115 (4), p.776-787

2019

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Hydrogen sulfide treatment reduces blood pressure and oxidative stress in angiotensin II-induced hypertensive mice

Hypertension research, 2015-01, Vol.38 (1), p.13-20

2015

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IL-4 and IL-13 induce equivalent expression of traditional M2 markers and modulation of reactive oxygen species in human macrophages

Scientific reports, 2023-11, Vol.13 (1), p.19589-19589, Article 19589

2023

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Nitroxyl (HNO): the Cinderella of the nitric oxide story

Trends in pharmacological sciences (Regular ed.), 2008-12, Vol.29 (12), p.601-608

2008

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The single-chain relaxin mimetic, B7-33, maintains the cardioprotective effects of relaxin and more rapidly reduces left ventricular fibrosis compared to perindopril in an experimental model of cardiomyopathy

Biomedicine & pharmacotherapy, 2023-04, Vol.160, p.114370-114370, Article 114370

2023

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An in vivo examination of the differences between rapid cardiovascular collapse and prolonged hypotension induced by snake venom

Scientific reports, 2019-12, Vol.9 (1), p.20231-9, Article 20231

2019

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A role for nitroxyl (HNO) as an endothelium‐derived relaxing and hyperpolarizing factor in resistance arteries

British journal of pharmacology, 2009-06, Vol.157 (4), p.540-550

2009

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Nitroxyl: A Novel Strategy to Circumvent Diabetes Associated Impairments in Nitric Oxide Signaling

Frontiers in pharmacology, 2020-05, Vol.11, p.727

2020

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Hydrogen sulfide protects endothelial nitric oxide function under conditions of acute oxidative stress in vitro

Naunyn-Schmiedeberg's archives of pharmacology, 2014-01, Vol.387 (1), p.67-74

2014

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Diabetes Attenuates the Contribution of Endogenous Nitric Oxide but Not Nitroxyl to Endothelium Dependent Relaxation of Rat Carotid Arteries

Frontiers in pharmacology, 2021-01, Vol.11, p.585740-585740

2021

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Nitroxyl: a vasodilator of human vessels that is not susceptible to tolerance

Clinical science (1979), 2015-07, Vol.129 (2), p.179-187

2015

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The soluble guanylyl cyclase activator bay 58-2667 selectively limits cardiomyocyte hypertrophy

PloS one, 2012-11, Vol.7 (11), p.e44481-e44481

2012

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The concomitant coronary vasodilator and positive inotropic actions of the nitroxyl donor Angeli's salt in the intact rat heart: contribution of soluble guanylyl cyclase‐dependent and ‐independent mechanisms

British journal of pharmacology, 2014-04, Vol.171 (7), p.1722-1734

2014

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Distinct Redox Signalling following Macrophage Activation Influences Profibrotic Activity

Journal of Immunology Research, 2019, Vol.2019 (2019), p.1-15

2019

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Nitroxyl (HNO) reduces endothelial and monocyte activation and promotes M2 macrophage polarization

Clinical science (1979), 2016-09, Vol.130 (18), p.1629-1640

2016

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Nitroxyl (HNO) stimulates soluble guanylyl cyclase to suppress cardiomyocyte hypertrophy and superoxide generation

PloS one, 2012-04, Vol.7 (4), p.e34892

2012

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D. russelii Venom Mediates Vasodilatation of Resistance Like Arteries via Activation of Kv and KCa Channels

Toxins, 2019-04, Vol.11 (4), p.197

2019

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ROLE OF ENDOTHELIUM-DERIVED HYPERPOLARIZING FACTOR IN ENDOTHELIAL DYSFUNCTION DURING DIABETES

Clinical and experimental pharmacology & physiology, 2005-05, Vol.32 (5-6), p.482-487

2005

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Vampire Venom: Vasodilatory Mechanisms of Vampire Bat ( Desmodus rotundus ) Blood Feeding

Toxins, 2019-01, Vol.11 (1), p.26

2019

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Targeting the NLRP3 inflammasome to treat cardiovascular fibrosis

Pharmacology & therapeutics (Oxford), 2020-05, Vol.209, p.107511-107511, Article 107511

2020

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The opposing roles of NO and oxidative stress in cardiovascular disease

Pharmacological research, 2017-02, Vol.116, p.57-69

2017

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Animal models of pulmonary hypertension: Getting to the heart of the problem

Inflammasomes: a novel therapeutic target in pulmonary hypertension?

Simultaneous targeting of oxidative stress and fibrosis reverses cardiomyopathy‐induced ventricular remodelling and dysfunction

Cardioprotective actions of nitroxyl donor Angeli's salt are preserved in the diabetic heart and vasculature in the face of nitric oxide resistance

Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension

Hydrogen sulfide treatment reduces blood pressure and oxidative stress in angiotensin II-induced hypertensive mice

IL-4 and IL-13 induce equivalent expression of traditional M2 markers and modulation of reactive oxygen species in human macrophages

Nitroxyl (HNO): the Cinderella of the nitric oxide story

The single-chain relaxin mimetic, B7-33, maintains the cardioprotective effects of relaxin and more rapidly reduces left ventricular fibrosis compared to perindopril in an experimental model of cardiomyopathy

An in vivo examination of the differences between rapid cardiovascular collapse and prolonged hypotension induced by snake venom

A role for nitroxyl (HNO) as an endothelium‐derived relaxing and hyperpolarizing factor in resistance arteries

Nitroxyl: A Novel Strategy to Circumvent Diabetes Associated Impairments in Nitric Oxide Signaling

Hydrogen sulfide protects endothelial nitric oxide function under conditions of acute oxidative stress in vitro

Diabetes Attenuates the Contribution of Endogenous Nitric Oxide but Not Nitroxyl to Endothelium Dependent Relaxation of Rat Carotid Arteries

Nitroxyl: a vasodilator of human vessels that is not susceptible to tolerance

The soluble guanylyl cyclase activator bay 58-2667 selectively limits cardiomyocyte hypertrophy

The concomitant coronary vasodilator and positive inotropic actions of the nitroxyl donor Angeli's salt in the intact rat heart: contribution of soluble guanylyl cyclase‐dependent and ‐independent mechanisms

Distinct Redox Signalling following Macrophage Activation Influences Profibrotic Activity

Nitroxyl (HNO) reduces endothelial and monocyte activation and promotes M2 macrophage polarization

Nitroxyl (HNO) stimulates soluble guanylyl cyclase to suppress cardiomyocyte hypertrophy and superoxide generation

D. russelii Venom Mediates Vasodilatation of Resistance Like Arteries via Activation of Kv and KCa Channels

ROLE OF ENDOTHELIUM-DERIVED HYPERPOLARIZING FACTOR IN ENDOTHELIAL DYSFUNCTION DURING DIABETES

Vampire Venom: Vasodilatory Mechanisms of Vampire Bat ( Desmodus rotundus ) Blood Feeding

Targeting the NLRP3 inflammasome to treat cardiovascular fibrosis

The opposing roles of NO and oxidative stress in cardiovascular disease

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