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Nitric oxide: a key mediator of biofilm dispersal with applications in infectious diseases

Current pharmaceutical design, 2015-01, Vol.21 (1), p.31-42

2015

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Anti‐tumour/metastasis effects of the potassium‐sparing diuretic amiloride: An orally active anti‐cancer drug waiting for its call‐of‐duty?

International journal of cancer, 2011-11, Vol.129 (9), p.2051-2061

2011

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The Urokinase Plasminogen Activation System in Rheumatoid Arthritis: Pathophysiological Roles and Prospective Therapeutic Targets

Current drug targets, 2019-01, Vol.20 (9), p.970-981

2019

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Ion Transport and Inhibitor Binding by Human NHE1: Insights from Molecular Dynamics Simulations and Free Energy Calculations

The journal of physical chemistry. B, 2024-01, Vol.128 (2), p.440-450

2024

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A comparison of patient matched meibum and tear lipidomes

Investigative ophthalmology & visual science, 2013-11, Vol.54 (12), p.7417-7424

2013

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Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function

The Journal of experimental medicine, 2006-11, Vol.203 (12), p.2691-2702

2006

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Disruption of Water Networks is the Cause of Human/Mouse Species Selectivity in Urokinase Plasminogen Activator (uPA) Inhibitors Derived from Hexamethylene Amiloride (HMA)

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.1933-1945

2022

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Screening of 5- and 6-Substituted Amiloride Libraries Identifies Dual-uPA/NHE1 Active and Single Target-Selective Inhibitors

International journal of molecular sciences, 2021-03, Vol.22 (6), p.2999

2021

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6‑Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer

Journal of medicinal chemistry, 2018-09, Vol.61 (18), p.8299-8320

2018

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Mass spectrometry-directed structure elucidation and total synthesis of ultra-long chain (O-acyl)-ω-hydroxy fatty acids

Journal of lipid research, 2018-08, Vol.59 (8), p.1510-1518

2018

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Introduction of a Fixed-Charge, Photolabile Derivative for Enhanced Structural Elucidation of Fatty Acids

Analytical chemistry (Washington), 2019-08, Vol.91 (15), p.9901-9909

2019

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Structure-activity relationships of pyrazole-4-carbodithioates as antibacterials against methicillin–resistant Staphylococcus aureus

Bioorganic & medicinal chemistry letters, 2018-12, Vol.28 (22), p.3526-3528

2018

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Cephalosporin nitric oxide-donor prodrug DEA-C3D disperses biofilms formed by clinical cystic fibrosis isolates of Pseudomonas aeruginosa

Journal of antimicrobial chemotherapy, 2020-01, Vol.75 (1), p.117-125

2020

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Determination of ester position in isomeric (O-acyl)-hydroxy fatty acids by ion trap mass spectrometry

Rapid communications in mass spectrometry, 2016-11, Vol.30 (21), p.2351-2359

2016

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Cephalosporin-3′-diazeniumdiolates: Targeted NO-Donor Prodrugs for Dispersing Bacterial Biofilms

Angewandte Chemie (International ed.), 2012-09, Vol.51 (36), p.9057-9060

International ed. in English, 2012

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Antifungal activity of 6-substituted amiloride and hexamethylene amiloride (HMA) analogs

Frontiers in cellular and infection microbiology, 2023-02, Vol.13, p.1101568-1101568

2023

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Attaching NorA efflux pump inhibitors to methylene blue enhances antimicrobial photodynamic inactivation of Escherichia coli and Acinetobacter baumannii in vitro and in vivo

Bioorganic & medicinal chemistry letters, 2018-09, Vol.28 (16), p.2736-2740

2018

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Antibacterial Properties of Four Novel Hit Compounds from a Methicillin-Resistant Staphylococcus aureus-Caenorhabditis elegans High-Throughput Screen

Microbial drug resistance (Larchmont, N.Y.), 2018-06, Vol.24 (5), p.666-674

2018

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Clostridium difficile infection: molecular pathogenesis and novel therapeutics

Expert review of anti-infective therapy, 2014-01, Vol.12 (1), p.131-150

2014

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Synthesis of cephalosporin-3'-diazeniumdiolates: biofilm dispersing NO-donor prodrugs activated by β-lactamase

Chemical communications (Cambridge, England), 2013-05, Vol.49 (42), p.4791-4793

2013

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A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis

Cell chemical biology, 2024-04, Vol.31 (4), p.683-698.e7

2024

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Strategies to Potentiate Antimicrobial Photoinactivation by Overcoming Resistant Phenotypes

Photochemistry and photobiology, 2012-05, Vol.88 (3), p.499-511

2012

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PAI-1 deficiency drives pulmonary vascular smooth muscle remodeling and pulmonary hypertension

American journal of physiology. Lung cellular and molecular physiology, 2024-09, Vol.327 (3), p.L319-L326

2024

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6-Substituted amiloride derivatives as inhibitors of the urokinase-type plasminogen activator for use in metastatic disease

Bioorganic & medicinal chemistry letters, 2019-12, Vol.29 (24), p.126753-126753, Article 126753

2019

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Nitric oxide: a key mediator of biofilm dispersal with applications in infectious diseases

Anti‐tumour/metastasis effects of the potassium‐sparing diuretic amiloride: An orally active anti‐cancer drug waiting for its call‐of‐duty?

The Urokinase Plasminogen Activation System in Rheumatoid Arthritis: Pathophysiological Roles and Prospective Therapeutic Targets

Ion Transport and Inhibitor Binding by Human NHE1: Insights from Molecular Dynamics Simulations and Free Energy Calculations

A comparison of patient matched meibum and tear lipidomes

Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function

Disruption of Water Networks is the Cause of Human/Mouse Species Selectivity in Urokinase Plasminogen Activator (uPA) Inhibitors Derived from Hexamethylene Amiloride (HMA)

Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis

Screening of 5- and 6-Substituted Amiloride Libraries Identifies Dual-uPA/NHE1 Active and Single Target-Selective Inhibitors

6‑Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer

Mass spectrometry-directed structure elucidation and total synthesis of ultra-long chain (O-acyl)-ω-hydroxy fatty acids

Introduction of a Fixed-Charge, Photolabile Derivative for Enhanced Structural Elucidation of Fatty Acids

Structure-activity relationships of pyrazole-4-carbodithioates as antibacterials against methicillin–resistant Staphylococcus aureus

Cephalosporin nitric oxide-donor prodrug DEA-C3D disperses biofilms formed by clinical cystic fibrosis isolates of Pseudomonas aeruginosa

Determination of ester position in isomeric (O-acyl)-hydroxy fatty acids by ion trap mass spectrometry

Cephalosporin-3′-diazeniumdiolates: Targeted NO-Donor Prodrugs for Dispersing Bacterial Biofilms

Antifungal activity of 6-substituted amiloride and hexamethylene amiloride (HMA) analogs

Attaching NorA efflux pump inhibitors to methylene blue enhances antimicrobial photodynamic inactivation of Escherichia coli and Acinetobacter baumannii in vitro and in vivo

Antibacterial Properties of Four Novel Hit Compounds from a Methicillin-Resistant Staphylococcus aureus-Caenorhabditis elegans High-Throughput Screen

Clostridium difficile infection: molecular pathogenesis and novel therapeutics

Synthesis of cephalosporin-3'-diazeniumdiolates: biofilm dispersing NO-donor prodrugs activated by β-lactamase

A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis

Strategies to Potentiate Antimicrobial Photoinactivation by Overcoming Resistant Phenotypes

PAI-1 deficiency drives pulmonary vascular smooth muscle remodeling and pulmonary hypertension

6-Substituted amiloride derivatives as inhibitors of the urokinase-type plasminogen activator for use in metastatic disease

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