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Engineering of cyclodextrin glucanotransferases and the impact for biotechnological applications

Applied microbiology and biotechnology, 2010-01, Vol.85 (4), p.823-835

2010

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Comparison of separation techniques for the elucidation of IgG N-glycans pooled from healthy mammalian species

Carbohydrate research, 2014-05, Vol.389, p.174-185

2014

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evolution of cyclodextrin glucanotransferase product specificity

Applied microbiology and biotechnology, 2009-08, Vol.84 (1), p.119-133

2009

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Directed evolution of enzymes: Library screening strategies

IUBMB life, 2009-03, Vol.61 (3), p.222-228

2009

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Enhanced sialylation of a human chimeric IgG1 variant produced in human and rodent cell lines

Journal of immunological methods, 2016-01, Vol.428, p.30-36

2016

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Mapping the molecular basis for growth related phenotypes in industrial producer CHO cell lines using differential proteomic analysis

BMC biotechnology, 2021-07, Vol.21 (1), p.43-43, Article 43

2021

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Elimination of competing hydrolysis and coupling side reactions of a cyclodextrin glucanotransferase by directed evolution

Biochemical journal, 2008-08, Vol.413 (3), p.517-525

2008

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Creation of a versatile automated two-step purification system with increased throughput capacity for preclinical mAb material generation

Protein expression and purification, 2023-07, Vol.207, p.106269-106269, Article 106269

2023

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Understanding biopharmaceutical production at single nucleotide resolution using ribosome footprint profiling

Current opinion in biotechnology, 2018-10, Vol.53, p.182-190

2018

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Modulation of IgG1 immunoeffector function by glycoengineering of the GDP‐fucose biosynthesis pathway

Biotechnology and bioengineering, 2018-03, Vol.115 (3), p.705-718

2018

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Generation of High Expressing Chinese Hamster Ovary Cell Pools Using the Leap‐In Transposon System

Biotechnology journal, 2018-10, Vol.13 (10), p.e1700748-n/a

2018

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Transcriptomic analysis of IgG4 Fc‐fusion protein degradation in a panel of clonally‐derived CHO cell lines using RNASeq

Biotechnology and bioengineering, 2019-06, Vol.116 (6), p.1556-1562

2019

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Evolution toward Small Molecule Inhibitor Resistance Affects Native Enzyme Function and Stability, Generating Acarbose-insensitive Cyclodextrin Glucanotransferase Variants

The Journal of biological chemistry, 2008-04, Vol.283 (16), p.10727-10734

2008

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Differential expression of miRNAs and functional role of mir-200a in high and low productivity CHO cells expressing an Fc fusion protein

Biotechnology letters, 2021-08, Vol.43 (8), p.1551-1563

2021

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Clonal variation in productivity and proteolytic clipping of an Fc-fusion protein in CHO cells: Proteomic analysis suggests a role for defective protein folding and the UPR

Journal of biotechnology, 2018-09, Vol.281, p.21-30

2018

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Starch and α-glucan acting enzymes, modulating their properties by directed evolution

Journal of biotechnology, 2009-03, Vol.140 (3-4), p.184-193

2009

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Conversion of a Cyclodextrin Glucanotransferase into an α-Amylase: Assessment of Directed Evolution Strategies

Biochemistry (Easton), 2007-10, Vol.46 (39), p.11216-11222

2007

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Global phosphoproteomic study of high/low specific productivity industrially relevant mAb producing recombinant CHO cell lines

Current research in biotechnology, 2021, Vol.3, p.49-56

2021

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Dabrafenib in patients with BRAFV600E -positive advanced non-small-cell lung cancer: a single-arm, multicentre, open-label, phase 2 trial

The lancet oncology, 2016-05, Vol.17 (5), p.642-650

2016

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Delivering maximum clinical benefit at an affordable price: engaging stakeholders in cancer care

The lancet oncology, 2014-03, Vol.15 (3), p.e112-e118

2014

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Cixutumumab for patients with recurrent or refractory advanced thymic epithelial tumours: a multicentre, open-label, phase 2 trial

The lancet oncology, 2014-02, Vol.15 (2), p.191-200

2014

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The Evolving Role of Checkpoint Inhibitors in the Management of Gastroesophageal Cancer

Hematology/oncology clinics of North America, 2017-06, Vol.31 (3), p.485-498

2017

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Pharmacodynamics and pharmacokinetics of single doses of prasugrel 30 mg and clopidogrel 300 mg in healthy chinese and white volunteers: An open-label trial

Clinical therapeutics, 2010-02, Vol.32 (2), p.365-379

2010

Volltextzugriff (PDF)

Inhibition of Sonic Hedgehog Signaling Pathway: A Novel Preventive Approach for Esophageal Adenocarcinoma

Journal of the American College of Surgeons, 2016-10, Vol.223 (4), p.e45-e46

2016

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Perceptions of inspiratory muscle training in adults recovering from COVID-19

PloS one, 2022-11, Vol.17 (11), p.e0270620-e0270620

2022

Volltextzugriff (PDF)

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Engineering of cyclodextrin glucanotransferases and the impact for biotechnological applications

Comparison of separation techniques for the elucidation of IgG N-glycans pooled from healthy mammalian species

evolution of cyclodextrin glucanotransferase product specificity

Directed evolution of enzymes: Library screening strategies

Enhanced sialylation of a human chimeric IgG1 variant produced in human and rodent cell lines

Mapping the molecular basis for growth related phenotypes in industrial producer CHO cell lines using differential proteomic analysis

Elimination of competing hydrolysis and coupling side reactions of a cyclodextrin glucanotransferase by directed evolution

Creation of a versatile automated two-step purification system with increased throughput capacity for preclinical mAb material generation

Understanding biopharmaceutical production at single nucleotide resolution using ribosome footprint profiling

Modulation of IgG1 immunoeffector function by glycoengineering of the GDP‐fucose biosynthesis pathway

Generation of High Expressing Chinese Hamster Ovary Cell Pools Using the Leap‐In Transposon System

Transcriptomic analysis of IgG4 Fc‐fusion protein degradation in a panel of clonally‐derived CHO cell lines using RNASeq

Evolution toward Small Molecule Inhibitor Resistance Affects Native Enzyme Function and Stability, Generating Acarbose-insensitive Cyclodextrin Glucanotransferase Variants

Differential expression of miRNAs and functional role of mir-200a in high and low productivity CHO cells expressing an Fc fusion protein

Clonal variation in productivity and proteolytic clipping of an Fc-fusion protein in CHO cells: Proteomic analysis suggests a role for defective protein folding and the UPR

Starch and α-glucan acting enzymes, modulating their properties by directed evolution

Conversion of a Cyclodextrin Glucanotransferase into an α-Amylase: Assessment of Directed Evolution Strategies

Global phosphoproteomic study of high/low specific productivity industrially relevant mAb producing recombinant CHO cell lines

Dabrafenib in patients with BRAFV600E -positive advanced non-small-cell lung cancer: a single-arm, multicentre, open-label, phase 2 trial

Delivering maximum clinical benefit at an affordable price: engaging stakeholders in cancer care

Cixutumumab for patients with recurrent or refractory advanced thymic epithelial tumours: a multicentre, open-label, phase 2 trial

The Evolving Role of Checkpoint Inhibitors in the Management of Gastroesophageal Cancer

Pharmacodynamics and pharmacokinetics of single doses of prasugrel 30 mg and clopidogrel 300 mg in healthy chinese and white volunteers: An open-label trial

Inhibition of Sonic Hedgehog Signaling Pathway: A Novel Preventive Approach for Esophageal Adenocarcinoma

Perceptions of inspiratory muscle training in adults recovering from COVID-19

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