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Synthesis and Pharmacological Evaluation of N-(3-(1H-Indol-4-yl)-5-(2-methoxyisonicotinoyl)phenyl)methanesulfonamide (LP-261), a Potent Antimitotic Agent

Journal of medicinal chemistry, 2011-01, Vol.54 (1), p.179-200

2011

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Discovery of 2‑[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β Agonist in Clinical Trials for the Treatment of Dyslipidemia

Journal of medicinal chemistry, 2014-05, Vol.57 (10), p.3912-3923

2014

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Lipid lowering in healthy volunteers treated with multiple doses of MGL-3196, a liver-targeted thyroid hormone receptor-β agonist

Atherosclerosis, 2013-10, Vol.230 (2), p.373-380

2013

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Efficient synthesis of 1,3,5-trisubstituted benzenes via three Pd-mediated carbon―sulfur, carbon―nitrogen and carbon―carbon bond formation reactions

Tetrahedron letters, 2011-04, Vol.52 (14), p.1680-1684

2011

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Two classes of p38α MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes

Bioorganic & medicinal chemistry letters, 2005-12, Vol.15 (23), p.5274-5279

2005

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Stereochemistry of vinylallene cycloadditions

Journal of the American Chemical Society, 1988-09, Vol.110 (19), p.6432-6442

1988

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Solid-phase synthesis of phenols and pyridinones via arylboronation/oxidation protocol using aryl bromides

Tetrahedron letters, 2006-07, Vol.47 (28), p.4897-4901

2006

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Solid-phase synthesis of 1-substituted 4,5-dihydro-1,2,4-triazin-6-ones

Tetrahedron letters, 2001-09, Vol.42 (37), p.6455-6457

2001

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Silyl ketone chemistry. Preparation and reactions of silyl allenol ethers. Diels-Alder reaction of siloxy vinylallenes leading to sesquiterpenes

Journal of the American Chemical Society, 1986-11, Vol.108 (24), p.7791-7800

1986

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Silyl ketone chemistry. Synthesis and reactions of olefinic and acetylenic silyl ketones

Journal of the American Chemical Society, 1982-02, Vol.104 (4), p.1119-1120

1982

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Two classes of p38alpha MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes

Bioorganic & medicinal chemistry letters, 2005-12, Vol.15 (23), p.5274-5279

2005

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Chiral toluene-2,α-sultam auxiliaries: Asymmetric diels-alder reactions of N-enoyl derivatives

Tetrahedron letters, 1990, Vol.31 (35), p.5015-5018

1990

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Silyl ketone chemistry : Preparation and reactions of unsaturated silyl ketones

Tetrahedron, 1983, Vol.39 (6), p.949-960

1983

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Preparation, structure and asymmetric diels-alder reactions of 10-arylsulfonylisobornyl acrylates

Tetrahedron letters, 1984, Vol.25 (51), p.5889-5892

1984

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Practical Asymmetric Diels-Alder Additions to Camphor-10-sulfonic-Acid-Derived Acrylates. Preliminary Communication

Helvetica chimica acta, 1983-11, Vol.66 (7), p.2358-2361

1983

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Silyl ketone chemistry

Tetrahedron, 1983-01, Vol.39 (6), p.949-960

1983

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Glutamate Dehydrogenase 1 Signals through Antioxidant Glutathione Peroxidase 1 to Regulate Redox Homeostasis and Tumor Growth

Cancer cell, 2015-02, Vol.27 (2), p.257-270

2015

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Insulin Excites Anorexigenic Proopiomelanocortin Neurons via Activation of Canonical Transient Receptor Potential Channels

Cell metabolism, 2014-04, Vol.19 (4), p.682-693

2014

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Evolution of structural diversity of trichothecenes, a family of toxins produced by plant pathogenic and entomopathogenic fungi

PLoS pathogens, 2018-04, Vol.14 (4), p.e1006946

2018

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Primary Open-Angle Glaucoma Preferred Practice Pattern

Ophthalmology (Rochester, Minn.), 2021-01, Vol.128 (1), p.P71-P150

2021

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Nanodroplet processing platform for deep and quantitative proteome profiling of 10-100 mammalian cells

Nature communications, 2018-02, Vol.9 (1), p.882-10, Article 882

2018

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Sequencing and analysis of globally obtained human respiratory syncytial virus A and B genomes

PloS one, 2015-03, Vol.10 (3), p.e0120098-e0120098

2015

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Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine

The New England journal of medicine, 2021-12, Vol.385 (25), p.2348-2360

2021

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Rapid Spread of a Bacterial Symbiont in an Invasive Whitefly Is Driven by Fitness Benefits and Female Bias

Science (American Association for the Advancement of Science), 2011-04, Vol.332 (6026), p.254-256

2011

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The Use of Language in Diabetes Care and Education

Diabetes care, 2017-12, Vol.40 (12), p.1790-1799

2017

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Synthesis and Pharmacological Evaluation of N-(3-(1H-Indol-4-yl)-5-(2-methoxyisonicotinoyl)phenyl)methanesulfonamide (LP-261), a Potent Antimitotic Agent

Discovery of 2‑[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β Agonist in Clinical Trials for the Treatment of Dyslipidemia

Lipid lowering in healthy volunteers treated with multiple doses of MGL-3196, a liver-targeted thyroid hormone receptor-β agonist

Efficient synthesis of 1,3,5-trisubstituted benzenes via three Pd-mediated carbon―sulfur, carbon―nitrogen and carbon―carbon bond formation reactions

Two classes of p38α MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes

Stereochemistry of vinylallene cycloadditions

Solid-phase synthesis of phenols and pyridinones via arylboronation/oxidation protocol using aryl bromides

Solid-phase synthesis of 1-substituted 4,5-dihydro-1,2,4-triazin-6-ones

Silyl ketone chemistry. Preparation and reactions of silyl allenol ethers. Diels-Alder reaction of siloxy vinylallenes leading to sesquiterpenes

Silyl ketone chemistry. Synthesis and reactions of olefinic and acetylenic silyl ketones

Two classes of p38alpha MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes

Chiral toluene-2,α-sultam auxiliaries: Asymmetric diels-alder reactions of N-enoyl derivatives

Silyl ketone chemistry : Preparation and reactions of unsaturated silyl ketones

Preparation, structure and asymmetric diels-alder reactions of 10-arylsulfonylisobornyl acrylates

Practical Asymmetric Diels-Alder Additions to Camphor-10-sulfonic-Acid-Derived Acrylates. Preliminary Communication

Silyl ketone chemistry

Glutamate Dehydrogenase 1 Signals through Antioxidant Glutathione Peroxidase 1 to Regulate Redox Homeostasis and Tumor Growth

Insulin Excites Anorexigenic Proopiomelanocortin Neurons via Activation of Canonical Transient Receptor Potential Channels

Evolution of structural diversity of trichothecenes, a family of toxins produced by plant pathogenic and entomopathogenic fungi

Primary Open-Angle Glaucoma Preferred Practice Pattern

Nanodroplet processing platform for deep and quantitative proteome profiling of 10-100 mammalian cells

Sequencing and analysis of globally obtained human respiratory syncytial virus A and B genomes

Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine

Rapid Spread of a Bacterial Symbiont in an Invasive Whitefly Is Driven by Fitness Benefits and Female Bias

The Use of Language in Diabetes Care and Education

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