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High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis

Cell, 2014-05, Vol.157 (5), p.1117-1129

2014

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Near-atomic model of microtubule-tau interactions

Science (American Association for the Advancement of Science), 2018-06, Vol.360 (6394), p.1242-1246

2018

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Role of conformational sampling in computing mutation-induced changes in protein structure and stability

Proteins, structure, function, and bioinformatics, 2011-03, Vol.79 (3), p.830-838

2011

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What Could Go Wrong? A Practical Guide to Single-Particle Cryo-EM: From Biochemistry to Atomic Models

Journal of chemical information and modeling, 2020-05, Vol.60 (5), p.2458-2469

2020

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Structures of the holo CRISPR RNA-guided transposon integration complex

Nature (London), 2023-01, Vol.613 (7945), p.775-782

2023

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High-resolution mapping of protein sequence-function relationships

Nature methods, 2010-09, Vol.7 (9), p.741-746

2010

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Genomic language model predicts protein co-regulation and function

Nature communications, 2024-04, Vol.15 (1), p.2880-2880, Article 2880

2024

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Structural differences between yeast and mammalian microtubules revealed by cryo-EM

The Journal of cell biology, 2017-09, Vol.216 (9), p.2669-2677

2017

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Scientific Benchmarks for Guiding Macromolecular Energy Function Improvement

Methods in Enzymology, 2013, Vol.523, p.109-143

2013

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Evaluation and Optimization of Discrete State Models of Protein Folding

The journal of physical chemistry. B, 2012-09, Vol.116 (37), p.11405-11413

2012

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Challenges and opportunities in the high-resolution cryo-EM visualization of microtubules and their binding partners

Current opinion in structural biology, 2017-10, Vol.46, p.65-70

2017

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Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures

Journal of molecular biology, 2017-03, Vol.429 (5), p.633-646

2017

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Structure of a P element transposase-DNA complex reveals unusual DNA structures and GTP-DNA contacts

Nature structural & molecular biology, 2019-11, Vol.26 (11), p.1013-1022

2019

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Mechanistic details of CRISPR-associated transposon recruitment and integration revealed by cryo-EM

Proceedings of the National Academy of Sciences - PNAS, 2022-08, Vol.119 (32), p.e2202590119-e2202590119

2022

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Structural basis for target site selection in RNA-guided DNA transposition systems

Science (American Association for the Advancement of Science), 2021-08, Vol.373 (6556), p.768-774

2021

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Compartmentalization of telomeres through DNA-scaffolded phase separation

Developmental cell, 2022-01, Vol.57 (2), p.277-290.e9

2022

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Near-atomic cryo-EM structure of PRC1 bound to the microtubule

Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (34), p.9430-9439

2016

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Mechanism of target site selection by type V-K CRISPR-associated transposases

Science (American Association for the Advancement of Science), 2023-11, Vol.382 (6672), p.eadj8543-eadj8543

2023

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Csx28 is a membrane pore that enhances CRISPR-Cas13b-dependent antiphage defense

Science (American Association for the Advancement of Science), 2023-04, Vol.380 (6643), p.410-415

2023

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Multiple adaptations underly co-option of a CRISPR surveillance complex for RNA-guided DNA transposition

Molecular cell, 2023-06, Vol.83 (11), p.1827-1838.e6

2023

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CRISPR-Csx28 forms a Cas13b-activated large-pore channel required for robust CRISPR-Cas immunity

Biophysical journal, 2023-02, Vol.122 (3), p.194a-194a

2023

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Structural and functional differences between porcine brain and budding yeast microtubules

Cell cycle (Georgetown, Tex.), 2018-02, Vol.17 (3), p.278-287

2018

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Towards a Mechanistic Understanding of P element Transposition Using Single-Particle Cryo-EM

Microscopy and microanalysis, 2019-08, Vol.25 (S2), p.1288-1289

2019

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What are the current bottlenecks in developing and applying CRISPR technologies?

Cell systems, 2022-08, Vol.13 (8), p.589-593

2022

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AAA+ regulator MuB distorts DNA to drive forward transposition

Biophysical journal, 2022-02, Vol.121 (3), p.332a-332a

2022

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High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis

Near-atomic model of microtubule-tau interactions

Role of conformational sampling in computing mutation-induced changes in protein structure and stability

What Could Go Wrong? A Practical Guide to Single-Particle Cryo-EM: From Biochemistry to Atomic Models

Structures of the holo CRISPR RNA-guided transposon integration complex

High-resolution mapping of protein sequence-function relationships

Genomic language model predicts protein co-regulation and function

Structural differences between yeast and mammalian microtubules revealed by cryo-EM

Scientific Benchmarks for Guiding Macromolecular Energy Function Improvement

Evaluation and Optimization of Discrete State Models of Protein Folding

Challenges and opportunities in the high-resolution cryo-EM visualization of microtubules and their binding partners

Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures

Structure of a P element transposase-DNA complex reveals unusual DNA structures and GTP-DNA contacts

Mechanistic details of CRISPR-associated transposon recruitment and integration revealed by cryo-EM

Structural basis for target site selection in RNA-guided DNA transposition systems

Compartmentalization of telomeres through DNA-scaffolded phase separation

Near-atomic cryo-EM structure of PRC1 bound to the microtubule

Mechanism of target site selection by type V-K CRISPR-associated transposases

Csx28 is a membrane pore that enhances CRISPR-Cas13b-dependent antiphage defense

Multiple adaptations underly co-option of a CRISPR surveillance complex for RNA-guided DNA transposition

CRISPR-Csx28 forms a Cas13b-activated large-pore channel required for robust CRISPR-Cas immunity

Structural and functional differences between porcine brain and budding yeast microtubules

Towards a Mechanistic Understanding of P element Transposition Using Single-Particle Cryo-EM

What are the current bottlenecks in developing and applying CRISPR technologies?

AAA+ regulator MuB distorts DNA to drive forward transposition

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