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Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies

Leukemia, 2014-01, Vol.28 (1), p.198-201

2014

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The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial–mesenchymal transition and invasive properties of prostate cancer

Oncogene, 2013-06, Vol.32 (23), p.2882-2890

2013

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ProSight PTM: an integrated environment for protein identification and characterization by top-down mass spectrometry

Nucleic acids research, 2004-07, Vol.32 (Web Server issue), p.W340-W345

2004

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Proteoforms in Peripheral Blood Mononuclear Cells as Novel Rejection Biomarkers in Liver Transplant Recipients

American journal of transplantation, 2017-09, Vol.17 (9), p.2458-2467

2017

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Attomole Protein Characterization by Capillary Electrophoresis-Mass Spectrometry

Science (American Association for the Advancement of Science), 1996-08, Vol.273 (5279), p.1199-1202

1996

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Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16

Mucosal immunology, 2016-11, Vol.9 (6), p.1549-1558

2016

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Lacticin 481: In vitro Reconstitution of Lantibiotic Synthetase Activity

Science (American Association for the Advancement of Science), 2004-01, Vol.303 (5658), p.679-681

2004

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Attomole-Sensitivity Electrospray Source for Large-Molecule Mass Spectrometry

Analytical chemistry (Washington), 1995-10, Vol.67 (20), p.3802-3805

1995

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Electron Capture Dissociation for Structural Characterization of Multiply Charged Protein Cations

Analytical chemistry (Washington), 2000-02, Vol.72 (3), p.563-573

2000

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Thiamin biosynthesis in Escherichia coli. Identification of ThiS thiocarboxylate as the immediate sulfur donor in the thiazole formation

The Journal of biological chemistry, 1998-06, Vol.273 (26), p.16555-16560

1998

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Staphylococcus aureus Sortase Transpeptidase SrtA: Insight into the Kinetic Mechanism and Evidence for a Reverse Protonation Catalytic Mechanism

Biochemistry (Easton), 2005-08, Vol.44 (33), p.11188-11200

2005

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Informatics and multiplexing of intact protein identification in bacteria and the archaea

Nature biotechnology, 2001-10, Vol.19 (10), p.952-957

2001

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Efficient sequence analysis of the six gene products (7‐74 kDA) from the escherichia coli thiamin biosynthetic operon by tandem high‐resolution mass spectrometry

Protein science, 1998-08, Vol.7 (8), p.1796-1801

1998

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Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging

Nature methods, 2022-03, Vol.19 (3), p.284-295

2022

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Targeted Analysis and Discovery of Posttranslational Modifications in Proteins from Methanogenic Archaea by Top-Down MS

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (9), p.2678-2683

2004

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Molecular-Level Description of Proteins from Saccharomyces cerevisiae Using Quadrupole FT Hybrid Mass Spectrometry for Top Down Proteomics

Analytical chemistry (Washington), 2004-05, Vol.76 (10), p.2852-2858

2004

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Overexpression of recombinant proteins with a C‐terminal thiocarboxylate: Implications for protein semisynthesis and thiamin biosynthesis

Protein science, 1998-08, Vol.7 (8), p.1839-1842

1998

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Activity Screening of Carrier Domains within Nonribosomal Peptide Synthetases Using Complex Substrate Mixtures and Large Molecule Mass Spectrometry

Biochemistry (Easton), 2006-02, Vol.45 (6), p.1537-1546

2006

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Top-down proteomics

Analytical chemistry (Washington), 2004-06, Vol.76 (11), p.197A-203A

KELLEHER, Neil L

2004

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Quantitative Analysis of Modified Proteins and Their Positional Isomers by Tandem Mass Spectrometry: Human Histone H4

Analytical chemistry (Washington), 2006-07, Vol.78 (13), p.4271-4280

2006

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Mechanistic studies on thiaminase I. Overexpression and identification of the active site nucleophile

The Journal of biological chemistry, 1996-02, Vol.271 (7), p.3445-3452

1996

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Posttranslational Heterocyclization of Cysteine and Serine Residues in the Antibiotic Microcin B17: Distributivity and Directionality

Biochemistry (Easton), 1999-11, Vol.38 (47), p.15623-15630

1999

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ProSight PTM 2.0: improved protein identification and characterization for top down mass spectrometry

Nucleic acids research, 2007-07, Vol.35 (Web Server issue), p.W701-W706

2007

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Role of the Active Site Cysteine of DpgA, a Bacterial Type III Polyketide Synthase

Biochemistry (Easton), 2004-02, Vol.43 (4), p.970-980

2004

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Metabologenomics: Discovery of new natural products and their biosynthetic gene clusters by genome-informed metabolomics

Planta medica, 2015, Vol.81 (11)

Kelleher, NL

2015

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Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies

The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial–mesenchymal transition and invasive properties of prostate cancer

ProSight PTM: an integrated environment for protein identification and characterization by top-down mass spectrometry

Proteoforms in Peripheral Blood Mononuclear Cells as Novel Rejection Biomarkers in Liver Transplant Recipients

Attomole Protein Characterization by Capillary Electrophoresis-Mass Spectrometry

Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16

Lacticin 481: In vitro Reconstitution of Lantibiotic Synthetase Activity

Attomole-Sensitivity Electrospray Source for Large-Molecule Mass Spectrometry

Electron Capture Dissociation for Structural Characterization of Multiply Charged Protein Cations

Thiamin biosynthesis in Escherichia coli. Identification of ThiS thiocarboxylate as the immediate sulfur donor in the thiazole formation

Staphylococcus aureus Sortase Transpeptidase SrtA: Insight into the Kinetic Mechanism and Evidence for a Reverse Protonation Catalytic Mechanism

Informatics and multiplexing of intact protein identification in bacteria and the archaea

Efficient sequence analysis of the six gene products (7‐74 kDA) from the escherichia coli thiamin biosynthetic operon by tandem high‐resolution mass spectrometry

Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging

Targeted Analysis and Discovery of Posttranslational Modifications in Proteins from Methanogenic Archaea by Top-Down MS

Molecular-Level Description of Proteins from Saccharomyces cerevisiae Using Quadrupole FT Hybrid Mass Spectrometry for Top Down Proteomics

Overexpression of recombinant proteins with a C‐terminal thiocarboxylate: Implications for protein semisynthesis and thiamin biosynthesis

Activity Screening of Carrier Domains within Nonribosomal Peptide Synthetases Using Complex Substrate Mixtures and Large Molecule Mass Spectrometry

Top-down proteomics

Quantitative Analysis of Modified Proteins and Their Positional Isomers by Tandem Mass Spectrometry: Human Histone H4

Mechanistic studies on thiaminase I. Overexpression and identification of the active site nucleophile

Posttranslational Heterocyclization of Cysteine and Serine Residues in the Antibiotic Microcin B17: Distributivity and Directionality

ProSight PTM 2.0: improved protein identification and characterization for top down mass spectrometry

Role of the Active Site Cysteine of DpgA, a Bacterial Type III Polyketide Synthase

Metabologenomics: Discovery of new natural products and their biosynthetic gene clusters by genome-informed metabolomics

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