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Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies

Clinical pharmacokinetics, 2010-08, Vol.49 (8), p.493-507

2010

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A hybrid machine learning/pharmacokinetic approach outperforms maximum a posteriori Bayesian estimation by selectively flattening model priors

CPT: pharmacometrics and systems pharmacology, 2021-10, Vol.10 (10), p.1150-1160

2021

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Clinical Decision Support for Precision Dosing: Opportunities for Enhanced Equity and Inclusion in Health Care

Clinical pharmacology and therapeutics, 2023-03, Vol.113 (3), p.565-574

2023

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Mathematical model and tool to explore shorter multi-drug therapy options for active pulmonary tuberculosis

PLoS computational biology, 2020-08, Vol.16 (8), p.e1008107-e1008107

2020

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Model-Informed Precision Dosing of Vancomycin in Hospitalized Children: Implementation and Adoption at an Academic Children's Hospital

Frontiers in pharmacology, 2020-04, Vol.11, p.551

2020

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Assessment of a Model-Informed Precision Dosing Platform Use in Routine Clinical Care for Personalized Busulfan Therapy in the Pediatric Hematopoietic Cell Transplantation (HCT) Population

Frontiers in pharmacology, 2020-07, Vol.11, p.888

2020

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The Effect of Famotidine, a MATE1-Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin

Clinical pharmacokinetics, 2016-06, Vol.55 (6), p.711-721

2016

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Clinical decision support for chemotherapy‐induced neutropenia using a hybrid pharmacodynamic/machine learning model

CPT: pharmacometrics and systems pharmacology, 2023-11, Vol.12 (11), p.1764-1776

2023

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Evaluating and Improving Neonatal Gentamicin Pharmacokinetic Models Using Aggregated Routine Clinical Care Data

Pharmaceutics, 2022-09, Vol.14 (10), p.2089

2022

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Population Pharmacokinetic Model Development of Tacrolimus in Pediatric and Young Adult Patients Undergoing Hematopoietic Cell Transplantation

Frontiers in pharmacology, 2021-12, Vol.12, p.750672-750672

2021

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Pharmacokinetics of Miltefosine in Old World Cutaneous Leishmaniasis Patients

Antimicrobial Agents and Chemotherapy, 2008-08, Vol.52 (8), p.2855-2860

2008

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Prospective Validation and Refinement of a Population Pharmacokinetic Model of Fludarabine in Children and Young Adults Undergoing Hematopoietic Cell Transplantation

Pharmaceutics, 2022-11, Vol.14 (11), p.2462

2022

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Model‐Informed Precision Dosing at the Bedside: Scientific Challenges and Opportunities

CPT: pharmacometrics and systems pharmacology, 2018-12, Vol.7 (12), p.785-787

2018

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Model‐based treatment optimization of a novel VEGFR inhibitor

British journal of clinical pharmacology, 2012-08, Vol.74 (2), p.315-326

2012

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Continuous Learning in Model‐Informed Precision Dosing: A Case Study in Pediatric Dosing of Vancomycin

Clinical pharmacology and therapeutics, 2021-01, Vol.109 (1), p.233-242

2021

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Personalized Antifungal Therapy Through Model-Informed Precision Dosing of Posaconazole

Clinical pharmacokinetics, 2024-05, Vol.63 (5), p.645-656

2024

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Evaluation of Neonatal and Paediatric Vancomycin Pharmacokinetic Models and the Impact of Maturation and Serum Creatinine Covariates in a Large Multicentre Data Set

Clinical pharmacokinetics, 2023-01, Vol.62 (1), p.67-76

2023

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Prospective validation of a model‐informed precision dosing tool for vancomycin in intensive care patients

British journal of clinical pharmacology, 2020-12, Vol.86 (12), p.2497-2506

2020

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Performance of Eight Infliximab Population Pharmacokinetic Models in a Cohort of Dutch Children with Inflammatory Bowel Disease

Clinical pharmacokinetics, 2024-04, Vol.63 (4), p.529-538

2024

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Bayesian clinical decision support-guided versus clinician-guided vancomycin dosing in attainment of targeted pharmacokinetic parameters in a paediatric population

Journal of antimicrobial chemotherapy, 2020-02, Vol.75 (2), p.434-437

2020

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Personalized Tuberculosis Treatment Through Model-Informed Dosing of Rifampicin

Clinical pharmacokinetics, 2019-06, Vol.58 (6), p.815-826

2019

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Get Real: Integration of Real‐World Data to Improve Patient Care

Clinical pharmacology and therapeutics, 2020-04, Vol.107 (4), p.722-725

2020

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Piraña and PCluster: A modeling environment and cluster infrastructure for NONMEM

Computer methods and programs in biomedicine, 2011, Vol.101 (1), p.72-79

2011

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Individualized Empiric Vancomycin Dosing in Neonates Using a Model-Based Approach

Journal of the Pediatric Infectious Diseases Society, 2019-05, Vol.8 (2), p.97-104

2019

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Evaluation of α2-Integrin Expression as a Biomarker for Tumor Growth Inhibition for the Investigational Integrin Inhibitor E7820 in Preclinical and Clinical Studies

The AAPS journal, 2011-06, Vol.13 (2), p.230-239

2011

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Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies

A hybrid machine learning/pharmacokinetic approach outperforms maximum a posteriori Bayesian estimation by selectively flattening model priors

Clinical Decision Support for Precision Dosing: Opportunities for Enhanced Equity and Inclusion in Health Care

Mathematical model and tool to explore shorter multi-drug therapy options for active pulmonary tuberculosis

Model-Informed Precision Dosing of Vancomycin in Hospitalized Children: Implementation and Adoption at an Academic Children's Hospital

Assessment of a Model-Informed Precision Dosing Platform Use in Routine Clinical Care for Personalized Busulfan Therapy in the Pediatric Hematopoietic Cell Transplantation (HCT) Population

The Effect of Famotidine, a MATE1-Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin

Clinical decision support for chemotherapy‐induced neutropenia using a hybrid pharmacodynamic/machine learning model

Evaluating and Improving Neonatal Gentamicin Pharmacokinetic Models Using Aggregated Routine Clinical Care Data

Population Pharmacokinetic Model Development of Tacrolimus in Pediatric and Young Adult Patients Undergoing Hematopoietic Cell Transplantation

Pharmacokinetics of Miltefosine in Old World Cutaneous Leishmaniasis Patients

Prospective Validation and Refinement of a Population Pharmacokinetic Model of Fludarabine in Children and Young Adults Undergoing Hematopoietic Cell Transplantation

Model‐Informed Precision Dosing at the Bedside: Scientific Challenges and Opportunities

Model‐based treatment optimization of a novel VEGFR inhibitor

Continuous Learning in Model‐Informed Precision Dosing: A Case Study in Pediatric Dosing of Vancomycin

Personalized Antifungal Therapy Through Model-Informed Precision Dosing of Posaconazole

Evaluation of Neonatal and Paediatric Vancomycin Pharmacokinetic Models and the Impact of Maturation and Serum Creatinine Covariates in a Large Multicentre Data Set

Prospective validation of a model‐informed precision dosing tool for vancomycin in intensive care patients

Performance of Eight Infliximab Population Pharmacokinetic Models in a Cohort of Dutch Children with Inflammatory Bowel Disease

Bayesian clinical decision support-guided versus clinician-guided vancomycin dosing in attainment of targeted pharmacokinetic parameters in a paediatric population

Personalized Tuberculosis Treatment Through Model-Informed Dosing of Rifampicin

Get Real: Integration of Real‐World Data to Improve Patient Care

Piraña and PCluster: A modeling environment and cluster infrastructure for NONMEM

Individualized Empiric Vancomycin Dosing in Neonates Using a Model-Based Approach

Evaluation of α2-Integrin Expression as a Biomarker for Tumor Growth Inhibition for the Investigational Integrin Inhibitor E7820 in Preclinical and Clinical Studies

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