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Evaluating the Classification Accuracy of Expression Quantitative Trait Loci Calculated Polygenic Risk Scores in Alzheimer’s Disease

International journal of molecular sciences, 2023-08, Vol.24 (16), p.12799

Brookes, Keeley J

2023

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A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene

Brain (London, England : 1878), 2021-12, Vol.144 (12), p.3727-3741

2021

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Gene Association Study of the Urokinase Plasminogen Activator and Its Receptor Gene in Alzheimer's Disease

Journal of Alzheimer's disease, 2024-01, Vol.99 (1), p.241

2024

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Genome-wide association findings from the brains for dementia research cohort

Neurobiology of aging, 2021-11, Vol.107, p.159-167

2021

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Genetic variants in glutamate-, Aβ−, and tau-related pathways determine polygenic risk for Alzheimer's disease

Neurobiology of aging, 2021-05, Vol.101, p.299.e13-299.e21

2021

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DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types

Nature communications, 2022-09, Vol.13 (1), p.5620-5620, Article 5620

2022

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Psychological stress, cognitive decline and the development of dementia in amnestic mild cognitive impairment

Scientific reports, 2020-02, Vol.10 (1), p.3618-3618, Article 3618

2020

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A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease

Molecular psychiatry, 2020-03, Vol.25 (3), p.629-639

2020

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Alzheimer's disease polygenic risk score as a predictor of conversion from mild-cognitive impairment

Translational psychiatry, 2019-05, Vol.9 (1), p.154-154, Article 154

2019

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An alternative method of SNP inclusion to develop a generalized polygenic risk score analysis across Alzheimer's disease cohorts

Frontiers in dementia, 2023-07, Vol.2, p.1120206

2023

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Age-related changes in tau and autophagy in human brain in the absence of neurodegeneration

PloS one, 2023-01, Vol.18 (1), p.e0262792-e0262792

2023

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Identification of Novel Genes Associated with Cortical Thickness in Alzheimer's Disease: Systems Biology Approach to Neuroimaging Endophenotype

Journal of Alzheimer's disease, 2020-01, Vol.75 (2), p.531

2020

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Dementia with Lewy Bodies: Genomics, Transcriptomics, and Its Future with Data Science

Cells (Basel, Switzerland), 2024-01, Vol.13 (3), p.223

2024

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Genetic architecture of epigenetic cortical clock age in brain tissue from older individuals: alterations in CD46 and other loci

Epigenetics, 2024-12, Vol.19 (1), p.2392050

2024

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Observations of extensive gene expression differences in the cerebellum and potential relevance to Alzheimer's disease

BMC research notes, 2018-09, Vol.11 (1), p.646-646, Article 646

2018

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The DRD4 receptor Exon 3 VNTR and 5′ SNP variants and mRNA expression in human post-mortem brain tissue

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2010-09, Vol.153B (6), p.1228-1233

2010

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Genetic variability in response to amyloid beta deposition influences Alzheimer's disease risk

Brain communications, 2019-01, Vol.1 (1), p.fcz022-fcz022

2019

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Oxytocin receptor (OXTR) does not play a major role in the aetiology of autism: Genetic and molecular studies

Neuroscience letters, 2010-05, Vol.474 (3), p.163-167

2010

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Association of Fatty Acid Desaturase Genes with Attention-Deficit/Hyperactivity Disorder

Biological psychiatry (1969), 2006-11, Vol.60 (10), p.1053-1061

2006

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Genotyping of the Alzheimer's Disease Genome-Wide Association Study Index Single Nucleotide Polymorphisms in the Brains for Dementia Research Cohort

Journal of Alzheimer's disease, 2018-01, Vol.64 (2), p.355

2018

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5HTT genotype moderates the influence of early institutional deprivation on emotional problems in adolescence: evidence from the English and Romanian Adoptee (ERA) study

Journal of child psychology and psychiatry, 2010-07, Vol.51 (7), p.755-762

2010

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Relationship between VNTR polymorphisms of the human dopamine transporter gene and expression in post-mortem midbrain tissue

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2007-12, Vol.144B (8), p.1070-1078

2007

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Dopamine transporter gene polymorphism moderates the effects of severe deprivation on ADHD symptoms: Developmental continuities in gene-environment interplay

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2009-09, Vol.150B (6), p.753-761

2009

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Correction: Alzheimer's disease polygenic risk score as a predictor of conversion from mild-cognitive impairment

Translational psychiatry, 2019-06, Vol.9 (1), p.167-167, Article 167

2019

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Evaluating the Classification Accuracy of Expression Quantitative Trait Loci Calculated Polygenic Risk Scores in Alzheimer’s Disease

A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene

Gene Association Study of the Urokinase Plasminogen Activator and Its Receptor Gene in Alzheimer's Disease

Genome-wide association findings from the brains for dementia research cohort

Genetic variants in glutamate-, Aβ−, and tau-related pathways determine polygenic risk for Alzheimer's disease

DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types

Psychological stress, cognitive decline and the development of dementia in amnestic mild cognitive impairment

A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease

Alzheimer's disease polygenic risk score as a predictor of conversion from mild-cognitive impairment

An alternative method of SNP inclusion to develop a generalized polygenic risk score analysis across Alzheimer's disease cohorts

Age-related changes in tau and autophagy in human brain in the absence of neurodegeneration

Identification of Novel Genes Associated with Cortical Thickness in Alzheimer's Disease: Systems Biology Approach to Neuroimaging Endophenotype

Dementia with Lewy Bodies: Genomics, Transcriptomics, and Its Future with Data Science

Genetic architecture of epigenetic cortical clock age in brain tissue from older individuals: alterations in CD46 and other loci

Observations of extensive gene expression differences in the cerebellum and potential relevance to Alzheimer's disease

Polygenic risk score in postmortem diagnosed sporadic early-onset Alzheimer's disease

The DRD4 receptor Exon 3 VNTR and 5′ SNP variants and mRNA expression in human post-mortem brain tissue

Genetic variability in response to amyloid beta deposition influences Alzheimer's disease risk

Oxytocin receptor (OXTR) does not play a major role in the aetiology of autism: Genetic and molecular studies

Association of Fatty Acid Desaturase Genes with Attention-Deficit/Hyperactivity Disorder

Genotyping of the Alzheimer's Disease Genome-Wide Association Study Index Single Nucleotide Polymorphisms in the Brains for Dementia Research Cohort

5HTT genotype moderates the influence of early institutional deprivation on emotional problems in adolescence: evidence from the English and Romanian Adoptee (ERA) study

Relationship between VNTR polymorphisms of the human dopamine transporter gene and expression in post-mortem midbrain tissue

Dopamine transporter gene polymorphism moderates the effects of severe deprivation on ADHD symptoms: Developmental continuities in gene-environment interplay

Correction: Alzheimer's disease polygenic risk score as a predictor of conversion from mild-cognitive impairment

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