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Fifty Years of Diazeniumdiolate Research. From Laboratory Curiosity to Broad-Spectrum Biomedical Advances

ACS chemical biology, 2011-11, Vol.6 (11), p.1147-1155

Keefer, Larry K

2011

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Key bioactive reaction products of the NO/H₂S interaction are S/N-hybrid species, polysulfides, and nitroxyl

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (34), p.E4651-E4660

2015

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Estrogen Metabolism and Risk of Breast Cancer in Postmenopausal Women

JNCI : Journal of the National Cancer Institute, 2012-02, Vol.104 (4), p.326-339

2012

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Chemistry of the Nitric Oxide-Releasing Diazeniumdiolate (“Nitrosohydroxylamine”) Functional Group and Its Oxygen-Substituted Derivatives

Chemical reviews, 2002-04, Vol.102 (4), p.1135-1154

2002

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Progress toward clinical application of the nitric oxide-releasing diazeniumdiolates

Annual review of pharmacology and toxicology, 2003-01, Vol.43 (1), p.585-607

KEEFER, Larry K

2003

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Urinary Estrogens and Estrogen Metabolites and Subsequent Risk of Breast Cancer among Premenopausal Women

Cancer research (Chicago, Ill.), 2012-02, Vol.72 (3), p.696-706

2012

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Comparison of Liquid Chromatography-Tandem Mass Spectrometry, RIA, and ELISA Methods for Measurement of Urinary Estrogens

Cancer epidemiology, biomarkers & prevention, 2010-01, Vol.19 (1), p.292-300

2010

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Nitric oxide and nanotechnology: A novel approach to inhibit neointimal hyperplasia

Journal of vascular surgery, 2008, Vol.47 (1), p.173-182

2008

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Macrophage-dependent nitric oxide expression regulates tumor cell detachment and metastasis after IL-2/anti-CD40 immunotherapy

The Journal of experimental medicine, 2010-10, Vol.207 (11), p.2455-2467

2010

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Nitric Oxide Inhibits Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia by Increasing the Ubiquitination and Degradation of UbcH10

Cell biochemistry and biophysics, 2011-06, Vol.60 (1-2), p.89-97

2011

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Dual Mechanisms of HNO Generation by a Nitroxyl Prodrug of the Diazeniumdiolate (NONOate) Class

Journal of the American Chemical Society, 2010-11, Vol.132 (46), p.16526-16532

2010

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Chemistry of the Diazeniumdiolates. 2. Kinetics and Mechanism of Dissociation to Nitric Oxide in Aqueous Solution

Journal of the American Chemical Society, 2001-06, Vol.123 (23), p.5473-5481

2001

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Isopropylamine NONOate (IPA/NO) moderates neointimal hyperplasia following vascular injury

Journal of vascular surgery, 2010-05, Vol.51 (5), p.1248-1259

2010

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Nitric oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance

Redox biology, 2013-01, Vol.1 (1), p.115-124

2013

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The Role of Estrogen Receptor α and β in Regulating Vascular Smooth Muscle Cell Proliferation is Based on Sex

The Journal of surgical research, 2012-03, Vol.173 (1), p.e1-e10

2012

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Structural modifications modulate stability of glutathione-activated arylated diazeniumdiolate prodrugs

Bioorganic & medicinal chemistry, 2012-05, Vol.20 (9), p.3094-3099

2012

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Effects of the nitric oxide donor JS-K on the blood-tumor barrier and on orthotopic U87 rat gliomas assessed by MRI

Nitric oxide, 2013-04, Vol.30, p.17-25

2013

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Green tea intake is associated with urinary estrogen profiles in Japanese-American women

Nutrition journal, 2013-02, Vol.12 (1), p.25-25, Article 25

2013

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Estrogen Metabolism and Risk of Breast Cancer in Postmenopausal Women

JNCI : Journal of the National Cancer Institute, 2012-02, Vol.104 (4), p.326-339

2012

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Quantitative Measurement of Endogenous Estrogens and Estrogen Metabolites in Human Serum by Liquid Chromatography−Tandem Mass Spectrometry

Analytical chemistry (Washington), 2007-10, Vol.79 (20), p.7813-7821

2007

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O2‑Functionalized Methylamine Diazeniumdiolates: Evidence for E ⇄ Z Equilibration in an Acyclic System

Journal of organic chemistry, 2012-12, Vol.77 (23), p.10804-10810

2012

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Nitric oxide (NO)- and nitroxyl (HNO)-generating diazeniumdiolates (NONOates): emerging commercial opportunities

Current topics in medicinal chemistry, 2005-01, Vol.5 (7), p.625-636

Keefer, Larry K

2005

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Heightened efficacy of nitric oxide-based therapies in type II diabetes mellitus and metabolic syndrome

American journal of physiology. Heart and circulatory physiology, 2008-12, Vol.295 (6), p.H2388-H2398

2008

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New nitric oxide-releasing zwitterions derived from polyamines

Journal of organic chemistry, 1993-03, Vol.58 (6), p.1472-1476

1993

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Fifty Years of Diazeniumdiolate Research. From Laboratory Curiosity to Broad-Spectrum Biomedical Advances

Key bioactive reaction products of the NO/H₂S interaction are S/N-hybrid species, polysulfides, and nitroxyl

Estrogen Metabolism and Risk of Breast Cancer in Postmenopausal Women

Chemistry of the Nitric Oxide-Releasing Diazeniumdiolate (“Nitrosohydroxylamine”) Functional Group and Its Oxygen-Substituted Derivatives

Progress toward clinical application of the nitric oxide-releasing diazeniumdiolates

Urinary Estrogens and Estrogen Metabolites and Subsequent Risk of Breast Cancer among Premenopausal Women

Comparison of Liquid Chromatography-Tandem Mass Spectrometry, RIA, and ELISA Methods for Measurement of Urinary Estrogens

Nitric oxide and nanotechnology: A novel approach to inhibit neointimal hyperplasia

Macrophage-dependent nitric oxide expression regulates tumor cell detachment and metastasis after IL-2/anti-CD40 immunotherapy

Nitric Oxide Inhibits Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia by Increasing the Ubiquitination and Degradation of UbcH10

JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells

Dual Mechanisms of HNO Generation by a Nitroxyl Prodrug of the Diazeniumdiolate (NONOate) Class

Chemistry of the Diazeniumdiolates. 2. Kinetics and Mechanism of Dissociation to Nitric Oxide in Aqueous Solution

Isopropylamine NONOate (IPA/NO) moderates neointimal hyperplasia following vascular injury

Nitric oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance

The Role of Estrogen Receptor α and β in Regulating Vascular Smooth Muscle Cell Proliferation is Based on Sex

Structural modifications modulate stability of glutathione-activated arylated diazeniumdiolate prodrugs

Effects of the nitric oxide donor JS-K on the blood-tumor barrier and on orthotopic U87 rat gliomas assessed by MRI

Green tea intake is associated with urinary estrogen profiles in Japanese-American women

Estrogen Metabolism and Risk of Breast Cancer in Postmenopausal Women

Quantitative Measurement of Endogenous Estrogens and Estrogen Metabolites in Human Serum by Liquid Chromatography−Tandem Mass Spectrometry

O2‑Functionalized Methylamine Diazeniumdiolates: Evidence for E ⇄ Z Equilibration in an Acyclic System

Nitric oxide (NO)- and nitroxyl (HNO)-generating diazeniumdiolates (NONOates): emerging commercial opportunities

Heightened efficacy of nitric oxide-based therapies in type II diabetes mellitus and metabolic syndrome

New nitric oxide-releasing zwitterions derived from polyamines

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