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Irreversible cell cycle exit associated with senescence is mediated by constitutive MYC degradation

Cell reports (Cambridge), 2023-09, Vol.42 (9), p.113079-113079, Article 113079

2023

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Loss of tumor suppressors promotes inflammatory tumor microenvironment and enhances LAG3+T cell mediated immune suppression

Nature communications, 2024-07, Vol.15 (1), p.5873-17, Article 5873

2024

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Spatial meta-transcriptomics reveal associations of intratumor bacteria burden with lung cancer cells showing a distinct oncogenic signature

Journal for immunotherapy of cancer, 2022-07, Vol.10 (7), p.e004698

2022

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Importance of the REM (Ras exchange) domain for membrane interactions by RasGRP3

Biochimica et biophysica acta. Biomembranes, 2017-12, Vol.1859 (12), p.2350-2360

2017

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SMAC Mimetics Synergistically Cooperate with HDAC Inhibitors Enhancing TNF-α Autocrine Signaling

Cancers, 2023-02, Vol.15 (4), p.1315

2023

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Preclinical Therapeutic Efficacy of RAF/MEK/ERK and IGF1R/AKT/mTOR Inhibition in Neuroblastoma

Cancers, 2024-06, Vol.16 (13), p.2320

2024

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Molecular Modeling, Total Synthesis, and Biological Evaluations of C9-Deoxy Bryostatin 1

Angewandte Chemie (International ed.), 2010-06, Vol.49 (27), p.4580-4584

2010

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RasGRPs are targets of the anti-cancer agent ingenol-3-angelate

PloS one, 2013-08, Vol.8 (8), p.e72331-e72331

2013

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Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP

Bioorganic & medicinal chemistry, 2014-06, Vol.22 (12), p.3123-3140

2014

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The synthetic bryostatin analog Merle 23 dissects distinct mechanisms of bryostatin activity in the LNCaP human prostate cancer cell line

Biochemical pharmacology, 2011-06, Vol.81 (11), p.1296-1308

2011

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Molecular Basis for Failure of “Atypical” C1 Domain of Vav1 to Bind Diacylglycerol/Phorbol Ester

The Journal of biological chemistry, 2012-04, Vol.287 (16), p.13137-13158

2012

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Abstract 5566: Streamlining tissue sample preparation: A comparative study on the efficiency and reproducibility of the Omni-Stainer™ dewaxing and HIER protocol

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.5566-5566

2024

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Evodiamine functions as an agonist for the vanilloid receptor TRPV1

Organic & biomolecular chemistry, 2004-08, Vol.2 (16), p.2281

2004

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Abstract 5344: Understanding the structural requirements of C1 domains for phorbol ester binding, analysis of the atypical C1 domain of STAC2

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.5344-5344

2017

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Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (12), p.4084-4088

2012

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The dimerization interface of initiator RctB governs chaperone and enhancer dependence of Vibrio cholerae chromosome 2 replication

Nucleic acids research, 2022-05, Vol.50 (8), p.4529-4544

2022

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The replication enhancer crtS depends on transcription factor Lrp for modulating binding of initiator RctB to ori2 of Vibrio cholerae

Nucleic acids research, 2024-01, Vol.52 (2), p.708-723

2024

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Spatial proximity of tumor-immune interactions predicts patient outcome in hepatocellular carcinoma

Hepatology (Baltimore, Md.), 2024-04, Vol.79 (4), p.768-779

2024

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Abstract 215: Characterization by mass spectrometry of protein kinase C substrates differentially phosphorylated in LNCaP cells in response to phorbol ester and bryostatin 1 treatment

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.215-215

2017

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Abstract 4450: Comparison of structural elements in RasGRP3 and RasGRP1 controlling membrane interaction

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.4450-4450

2014

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Absolute quantitation of endogenous proteins with precision and accuracy using a capillary Western system

Analytical biochemistry, 2013-11, Vol.442 (1), p.97-103

2013

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Abstract 1126: Importance of the REM (Ras exchange) motif for membrane interactions by RasGRP3

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1126-1126

2016

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Irreversible cell cycle exit associated with senescence is mediated by constitutive MYC degradation

Loss of tumor suppressors promotes inflammatory tumor microenvironment and enhances LAG3+T cell mediated immune suppression

Spatial meta-transcriptomics reveal associations of intratumor bacteria burden with lung cancer cells showing a distinct oncogenic signature

Importance of the REM (Ras exchange) domain for membrane interactions by RasGRP3

SMAC Mimetics Synergistically Cooperate with HDAC Inhibitors Enhancing TNF-α Autocrine Signaling

Preclinical Therapeutic Efficacy of RAF/MEK/ERK and IGF1R/AKT/mTOR Inhibition in Neuroblastoma

Systemic Nos2 Depletion and Cox inhibition limits TNBC disease progression and alters lymphoid cell spatial orientation and density

Molecular Modeling, Total Synthesis, and Biological Evaluations of C9-Deoxy Bryostatin 1

RasGRPs are targets of the anti-cancer agent ingenol-3-angelate

Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP

The synthetic bryostatin analog Merle 23 dissects distinct mechanisms of bryostatin activity in the LNCaP human prostate cancer cell line

Molecular Basis for Failure of “Atypical” C1 Domain of Vav1 to Bind Diacylglycerol/Phorbol Ester

Abstract 5566: Streamlining tissue sample preparation: A comparative study on the efficiency and reproducibility of the Omni-Stainer™ dewaxing and HIER protocol

Evodiamine functions as an agonist for the vanilloid receptor TRPV1

Abstract 5344: Understanding the structural requirements of C1 domains for phorbol ester binding, analysis of the atypical C1 domain of STAC2

Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity

The dimerization interface of initiator RctB governs chaperone and enhancer dependence of Vibrio cholerae chromosome 2 replication

The replication enhancer crtS depends on transcription factor Lrp for modulating binding of initiator RctB to ori2 of Vibrio cholerae

Spatial proximity of tumor-immune interactions predicts patient outcome in hepatocellular carcinoma

Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin

Abstract 215: Characterization by mass spectrometry of protein kinase C substrates differentially phosphorylated in LNCaP cells in response to phorbol ester and bryostatin 1 treatment

Abstract 4450: Comparison of structural elements in RasGRP3 and RasGRP1 controlling membrane interaction

Absolute quantitation of endogenous proteins with precision and accuracy using a capillary Western system

Abstract 1126: Importance of the REM (Ras exchange) motif for membrane interactions by RasGRP3

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