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Inside the Insulin Secretory Granule

Metabolites, 2021-08, Vol.11 (8), p.515

2021

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Islet Biology and Metabolism

Metabolites, 2021-11, Vol.11 (11), p.786

2021

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Enhanced structure and function of human pluripotent stem cell‐derived beta‐cells cultured on extracellular matrix

Stem cells translational medicine, 2021-03, Vol.10 (3), p.492-505

2021

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Insulin sensitivity is preserved in mice made obese by feeding a high starch diet

eLife, 2022-11, Vol.11

2022

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ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation

Molecular metabolism (Germany), 2019-07, Vol.25, p.83-94

2019

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The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets

PLoS genetics, 2016-12, Vol.12 (12), p.e1006466-e1006466

2016

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Deletion of miPEP in adipocytes protects against obesity and insulin resistance by boosting muscle metabolism

Molecular metabolism (Germany), 2024-08, Vol.86, p.101983, Article 101983

2024

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P.165: Engineering Functionally Mature Human Pluripotent Stem Cell-derived Beta-Cells by Modifying the Beta-cell Niche

Transplantation, 2021-12, Vol.105 (12 Suppl 2), p.S69-S69

2021

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What the BTBR/J mouse has taught us about diabetes and diabetic complications

iScience, 2023-07, Vol.26 (7), p.107036-107036, Article 107036

2023

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Corrigendum to ‘ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation’ [Molecular Metabolism 25 (2019) p.83–94]

Molecular metabolism (Germany), 2021-06, Vol.48, p.101219-101219, Article 101219

2021

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Sorting Out the Receptor Isoforms Underlying Dopamine Inhibition of Insulin Secretion

Diabetes (New York, N.Y.), 2022-09, Vol.71 (9), p.1831-1833

2022

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TRAIL-Expressing Monocyte/Macrophages Are Critical for Reducing Inflammation and Atherosclerosis

iScience, 2019-02, Vol.12, p.41-52

2019

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Machine Learning Algorithms, Applied to Intact Islets of Langerhans, Demonstrate Significantly Enhanced Insulin Staining at the Capillary Interface of Human Pancreatic β Cells

Metabolites, 2021-06, Vol.11 (6), p.363

2021

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Targeting the insulin granule for modulation of insulin exocytosis

Biochemical pharmacology, 2021-12, Vol.194, p.114821-114821, Article 114821

2021

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Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet

iScience, 2021-10, Vol.24 (10), p.103099, Article 103099

2021

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β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling

iScience, 2023-04, Vol.26 (4), p.106477-106477, Article 106477

2023

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Arp2/3 nucleates F-actin coating of fusing insulin granules in pancreatic β cells to control insulin secretion

Journal of cell science, 2020-03, Vol.133 (6)

2020

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Islet Biology and Metabolism

2022

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Optimised proteomic analysis of insulin granules from MIN6 cells identifies Scamp3, a novel regulator of insulin secretion and content

Diabetes (New York, N.Y.), 2024-09

2024

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Type 2 diabetes-associated single nucleotide polymorphism in Sorcs1 gene results in alternative processing of the Sorcs1 protein in INS1 β-cells

Scientific reports, 2019-12, Vol.9 (1), p.19466-11, Article 19466

2019

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Structural and functional polarisation of human pancreatic beta cells in islets from organ donors with and without type 2 diabetes

Diabetologia, 2021-03, Vol.64 (3), p.618-629

2021

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Sorcs1: From diabetes quantitative trait locus to cellular function

Diabetes research and clinical practice, 2016-10, Vol.120, p.S25-S25

Kebede, Melkam A

2016

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The metabolic consequences of ‘yo-yo’ dieting are markedly influenced by genetic diversity

International Journal of Obesity, 2024-08, Vol.48 (8), p.1170-1179

2024

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A fluorescent timer reporter enables sorting of insulin secretory granules by age

The Journal of biological chemistry, 2020-07, Vol.295 (27), p.8901-8911

2020

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Insights into obesity and diabetes at the intersection of mouse and human genetics

Trends in endocrinology and metabolism, 2014-10, Vol.25 (10), p.493-501

2014

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Inside the Insulin Secretory Granule

Islet Biology and Metabolism

Enhanced structure and function of human pluripotent stem cell‐derived beta‐cells cultured on extracellular matrix

Insulin sensitivity is preserved in mice made obese by feeding a high starch diet

ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation

The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets

Deletion of miPEP in adipocytes protects against obesity and insulin resistance by boosting muscle metabolism

P.165: Engineering Functionally Mature Human Pluripotent Stem Cell-derived Beta-Cells by Modifying the Beta-cell Niche

What the BTBR/J mouse has taught us about diabetes and diabetic complications

Corrigendum to ‘ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation’ [Molecular Metabolism 25 (2019) p.83–94]

Sorting Out the Receptor Isoforms Underlying Dopamine Inhibition of Insulin Secretion

TRAIL-Expressing Monocyte/Macrophages Are Critical for Reducing Inflammation and Atherosclerosis

Machine Learning Algorithms, Applied to Intact Islets of Langerhans, Demonstrate Significantly Enhanced Insulin Staining at the Capillary Interface of Human Pancreatic β Cells

Targeting the insulin granule for modulation of insulin exocytosis

Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet

β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling

Arp2/3 nucleates F-actin coating of fusing insulin granules in pancreatic β cells to control insulin secretion

Islet Biology and Metabolism

Optimised proteomic analysis of insulin granules from MIN6 cells identifies Scamp3, a novel regulator of insulin secretion and content

Type 2 diabetes-associated single nucleotide polymorphism in Sorcs1 gene results in alternative processing of the Sorcs1 protein in INS1 β-cells

Structural and functional polarisation of human pancreatic beta cells in islets from organ donors with and without type 2 diabetes

Sorcs1: From diabetes quantitative trait locus to cellular function

The metabolic consequences of ‘yo-yo’ dieting are markedly influenced by genetic diversity

A fluorescent timer reporter enables sorting of insulin secretory granules by age

Insights into obesity and diabetes at the intersection of mouse and human genetics

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