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Evidence for Bladder Urothelial Pathophysiology in Functional Bladder Disorders

BioMed research international, 2014-01, Vol.2014 (2014), p.1-15

2014

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Abnormal Akt signalling in bladder epithelial cell explants from patients with interstitial cystitis/bladder pain syndrome can be induced by antiproliferative factor treatment of normal bladder cells

BJU international, 2016-07, Vol.118 (1), p.161-172

2016

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Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice

Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (45), p.18035-18035

2013

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Death-associated Protein Kinase-1 Expression and Autophagy in Chronic Lymphocytic Leukemia Are Dependent on Activating Transcription Factor-6 and CCAAT/Enhancer-binding Protein-β

The Journal of biological chemistry, 2016-10, Vol.291 (42), p.22030-22042

2016

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A synthetic form of frizzled 8-associated antiproliferative factor enhances p53 stability through USP2a and MDM2

PloS one, 2012-12, Vol.7 (12), p.e50392-e50392

2012

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Antiproliferative factor decreases Akt phosphorylation and alters gene expression via CKAP4 in T24 bladder carcinoma cells

Journal of experimental & clinical cancer research, 2010-12, Vol.29 (1), p.160-160, Article 160

2010

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Identification of CKAP4/p63 as a Major Substrate of the Palmitoyl Acyltransferase DHHC2, a Putative Tumor Suppressor, Using a Novel Proteomics Method

Molecular & cellular proteomics, 2008-07, Vol.7 (7), p.1378-1388

2008

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Palmitoylation of cytoskeleton associated protein 4 by DHHC2 regulates antiproliferative factor-mediated signaling

Molecular biology of the cell, 2009-03, Vol.20 (5), p.1454-1463

2009

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An Antiproliferative Factor from Interstitial Cystitis Patients Is a Frizzled 8 Protein-Related Sialoglycopeptide

Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (32), p.11803-11808

2004

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Heparin‐binding epidermal growth factor‐like growth factor functionally antagonizes interstitial cystitis antiproliferative factor via mitogen‐activated protein kinase pathway activation

BJU international, 2009-02, Vol.103 (4), p.541-546

2009

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CKAP4/p63 Is a Receptor for the Frizzled-8 Protein-related Antiproliferative Factor from Interstitial Cystitis Patients

The Journal of biological chemistry, 2006-12, Vol.281 (49), p.37836-37843

2006

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Cell signaling in interstitial cystitis/painful bladder syndrome

Cellular signalling, 2008-12, Vol.20 (12), p.2174-2179

Keay, Susan

2008

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A Comparison of Multiple Urine Markers for Interstitial Cystitis

The Journal of urology, 2002-06, Vol.167 (6), p.2461-2469

2002

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Quantitative Proteomics Identifies a β-Catenin Network as an Element of the Signaling Response to Frizzled-8 Protein-Related Antiproliferative Factor

Molecular & cellular proteomics, 2011-06, Vol.10 (6), p.M110.007492-M110.007492, Article M110.007492

2011

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Urine Markers Do Not Predict Biopsy Findings or Presence of Bladder Ulcers in Interstitial Cystitis/Painful Bladder Syndrome

The Journal of urology, 2008-05, Vol.179 (5), p.1850-1856

2008

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p53 mediates interstitial cystitis antiproliferative factor (APF)-induced growth inhibition of human urothelial cells

FEBS letters, 2007-08, Vol.581 (20), p.3795-3799

2007

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Integration analysis of quantitative proteomics and transcriptomics data identifies potential targets of frizzled‐8 protein‐related antiproliferative factor in vivo

BJU international, 2012-12, Vol.110 (11c), p.E1138-E1146

2012

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Glycoamino Acid Analogues of the Thomsen–Friedenreich Tumor-Associated Carbohydrate Antigen: Synthesis and Evaluation of Novel Antiproliferative Factor Glycopeptides

ACS omega, 2017-09, Vol.2 (9), p.5618-5632

2017

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A mouse model for interstitial cystitis/painful bladder syndrome based on APF inhibition of bladder epithelial repair: a pilot study

BMC urology, 2012-06, Vol.12 (1), p.17-17, Article 17

2012

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hTERT-immortalized human urothelial cell line that responds to anti-proliferative factor

In vitro cellular & developmental biology. Animal, 2011-01, Vol.47 (1), p.2-9

2011

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Changes in Urine Markers and Symptoms After Bladder Distention for Interstitial Cystitis

The Journal of urology, 2007-02, Vol.177 (2), p.556-560

2007

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Sensitivity and specificity of antiproliferative factor, heparin-binding epidermal growth factor–like growth factor, and epidermal growth factor as urine markers for interstitial cystitis

Urology (Ridgewood, N.J.), 2001-06, Vol.57 (6), p.9-14

2001

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DO THE NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES CYSTOSCOPIC CRITERIA ASSOCIATE WITH OTHER CLINICAL AND OBJECTIVE FEATURES OF INTERSTITIAL CYSTITIS?

The Journal of urology, 2005, Vol.173 (1), p.93-97

2005

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HIV-1-associated nephropathy and response to highly-active antiretroviral therapy

The Lancet (British edition), 1998-09, Vol.352 (9130), p.783-784

1998

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Evidence for Bladder Urothelial Pathophysiology in Functional Bladder Disorders

Abnormal Akt signalling in bladder epithelial cell explants from patients with interstitial cystitis/bladder pain syndrome can be induced by antiproliferative factor treatment of normal bladder cells

Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice

Death-associated Protein Kinase-1 Expression and Autophagy in Chronic Lymphocytic Leukemia Are Dependent on Activating Transcription Factor-6 and CCAAT/Enhancer-binding Protein-β

A synthetic form of frizzled 8-associated antiproliferative factor enhances p53 stability through USP2a and MDM2

Antiproliferative factor decreases Akt phosphorylation and alters gene expression via CKAP4 in T24 bladder carcinoma cells

Identification of CKAP4/p63 as a Major Substrate of the Palmitoyl Acyltransferase DHHC2, a Putative Tumor Suppressor, Using a Novel Proteomics Method

Palmitoylation of cytoskeleton associated protein 4 by DHHC2 regulates antiproliferative factor-mediated signaling

An Antiproliferative Factor from Interstitial Cystitis Patients Is a Frizzled 8 Protein-Related Sialoglycopeptide

Heparin‐binding epidermal growth factor‐like growth factor functionally antagonizes interstitial cystitis antiproliferative factor via mitogen‐activated protein kinase pathway activation

CKAP4/p63 Is a Receptor for the Frizzled-8 Protein-related Antiproliferative Factor from Interstitial Cystitis Patients

Cell signaling in interstitial cystitis/painful bladder syndrome

A Comparison of Multiple Urine Markers for Interstitial Cystitis

Safety of Zoster Vaccine in Elderly Adults Following Documented Herpes Zoster

Quantitative Proteomics Identifies a β-Catenin Network as an Element of the Signaling Response to Frizzled-8 Protein-Related Antiproliferative Factor

Urine Markers Do Not Predict Biopsy Findings or Presence of Bladder Ulcers in Interstitial Cystitis/Painful Bladder Syndrome

p53 mediates interstitial cystitis antiproliferative factor (APF)-induced growth inhibition of human urothelial cells

Integration analysis of quantitative proteomics and transcriptomics data identifies potential targets of frizzled‐8 protein‐related antiproliferative factor in vivo

Glycoamino Acid Analogues of the Thomsen–Friedenreich Tumor-Associated Carbohydrate Antigen: Synthesis and Evaluation of Novel Antiproliferative Factor Glycopeptides

A mouse model for interstitial cystitis/painful bladder syndrome based on APF inhibition of bladder epithelial repair: a pilot study

hTERT-immortalized human urothelial cell line that responds to anti-proliferative factor

Changes in Urine Markers and Symptoms After Bladder Distention for Interstitial Cystitis

Sensitivity and specificity of antiproliferative factor, heparin-binding epidermal growth factor–like growth factor, and epidermal growth factor as urine markers for interstitial cystitis

DO THE NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES CYSTOSCOPIC CRITERIA ASSOCIATE WITH OTHER CLINICAL AND OBJECTIVE FEATURES OF INTERSTITIAL CYSTITIS?

HIV-1-associated nephropathy and response to highly-active antiretroviral therapy

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