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Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

The Journal of experimental medicine, 2012-01, Vol.209 (1), p.51-60

2012

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Proinsulin-specific, HLA-DQ8, and HLA-DQ8-transdimer-restricted CD4+ T cells infiltrate islets in type 1 diabetes

Diabetes (New York, N.Y.), 2015-01, Vol.64 (1), p.172-182

2015

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Development of a standardized MRI protocol for pancreas assessment in humans

PloS one, 2021-08, Vol.16 (8), p.e0256029-e0256029

2021

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Baricitinib and β-Cell Function in Patients with New-Onset Type 1 Diabetes

The New England journal of medicine, 2023-12, Vol.389 (23), p.2140-2150

2023

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Gut dysbiosis promotes islet-autoimmunity by increasing T-cell attraction in islets via CXCL10 chemokine

Journal of autoimmunity, 2023-11, Vol.140, p.103090-103090, Article 103090

2023

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Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation

Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (23), p.9554-9559

2011

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T-Cell-Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities

Diabetes (New York, N.Y.), 2019-06, Vol.68 (6), p.1251-1266

2019

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Deficiency in Type I Interferon Signaling Prevents the Early Interferon-Induced Gene Signature in Pancreatic Islets but Not Type 1 Diabetes in NOD Mice

Diabetes (New York, N.Y.), 2014-03, Vol.63 (3), p.1032-1040

2014

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Loss of intra-islet heparan sulfate is a highly sensitive marker of type 1 diabetes progression in humans

PloS one, 2018-02, Vol.13 (2), p.e0191360-e0191360

2018

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Understanding and preventing type 1 diabetes through the unique working model of TrialNet

Diabetologia, 2017-11, Vol.60 (11), p.2139-2147

2017

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Deficiency of the innate immune adaptor STING promotes autoreactive T cell expansion in NOD mice

Diabetologia, 2021-04, Vol.64 (4), p.878-889

2021

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Monitoring immunomodulation strategies in type 1 diabetes

Frontiers in immunology, 2023-06, Vol.14, p.1206874

2023

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Proinsulin C-peptide is an autoantigen in people with type 1 diabetes

Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (42), p.10732-10737

2018

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Do all patients require ureteroscopy prior to nephroureterectomy?

BJU international, 2022-06, Vol.129 (6), p.655-656

2022

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Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP

The Journal of clinical investigation, 2006-12, Vol.116 (12), p.3258-3265

2006

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Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity

Biochemical journal, 2014-07, Vol.461 (2), p.177-188

2014

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Glucose Induces Pancreatic Islet Cell Apoptosis That Requires the BH3-Only Proteins Bim and Puma and Multi-BH Domain Protein Bax

Diabetes (New York, N.Y.), 2010-03, Vol.59 (3), p.644-652

2010

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Extraislet expression of islet antigen boosts T cell exhaustion to partially prevent autoimmune diabetes

Proceedings of the National Academy of Sciences - PNAS, 2024-02, Vol.121 (6), p.e2315419121

2024

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Predicting sepsis after percutaneous nephrolithotomy

BJU international, 2019-06, Vol.123 (6), p.914-915

2019

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Evidence-informed clinical practice recommendations for treatment of type 1 diabetes complicated by problematic hypoglycemia

Diabetes care, 2015-06, Vol.38 (6), p.1016-1029

2015

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Proapoptotic BH3-Only Protein Bid Is Essential For Death Receptor–Induced Apoptosis of Pancreatic β-Cells

Diabetes (New York, N.Y.), 2008-05, Vol.57 (5), p.1284-1292

2008

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IL-17F induces inflammation, dysfunction and cell death in mouse islets

Scientific reports, 2020-08, Vol.10 (1), p.13077, Article 13077

2020

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Autoreactive T cells induce necrosis and not BCL-2-regulated or death receptor-mediated apoptosis or RIPK3-dependent necroptosis of transplanted islets in a mouse model of type 1 diabetes

Diabetologia, 2015-01, Vol.58 (1), p.140-148

2015

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Increased Thyroidal Activity on Routine FDG-PET/CT after Combination Immune Checkpoint Inhibition: Temporal Associations with Clinical and Biochemical Thyroiditis

Cancers, 2023-12, Vol.15 (24), p.5803

2023

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Severe acute respiratory syndrome coronavirus 2 as a potential cause of type 1 diabetes facilitated by spike protein receptor binding domain attachment to human islet cells: An illustrative case study and experimental data

Diabetic medicine, 2021-11, Vol.38 (11), p.e14608-n/a

2021

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Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

Proinsulin-specific, HLA-DQ8, and HLA-DQ8-transdimer-restricted CD4+ T cells infiltrate islets in type 1 diabetes

Development of a standardized MRI protocol for pancreas assessment in humans

Baricitinib and β-Cell Function in Patients with New-Onset Type 1 Diabetes

Gut dysbiosis promotes islet-autoimmunity by increasing T-cell attraction in islets via CXCL10 chemokine

Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation

T-Cell-Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities

Deficiency in Type I Interferon Signaling Prevents the Early Interferon-Induced Gene Signature in Pancreatic Islets but Not Type 1 Diabetes in NOD Mice

Loss of intra-islet heparan sulfate is a highly sensitive marker of type 1 diabetes progression in humans

Understanding and preventing type 1 diabetes through the unique working model of TrialNet

Deficiency of the innate immune adaptor STING promotes autoreactive T cell expansion in NOD mice

Monitoring immunomodulation strategies in type 1 diabetes

Proinsulin C-peptide is an autoantigen in people with type 1 diabetes

Do all patients require ureteroscopy prior to nephroureterectomy?

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP

Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity

Glucose Induces Pancreatic Islet Cell Apoptosis That Requires the BH3-Only Proteins Bim and Puma and Multi-BH Domain Protein Bax

Extraislet expression of islet antigen boosts T cell exhaustion to partially prevent autoimmune diabetes

Predicting sepsis after percutaneous nephrolithotomy

Evidence-informed clinical practice recommendations for treatment of type 1 diabetes complicated by problematic hypoglycemia

Proapoptotic BH3-Only Protein Bid Is Essential For Death Receptor–Induced Apoptosis of Pancreatic β-Cells

IL-17F induces inflammation, dysfunction and cell death in mouse islets

Autoreactive T cells induce necrosis and not BCL-2-regulated or death receptor-mediated apoptosis or RIPK3-dependent necroptosis of transplanted islets in a mouse model of type 1 diabetes

Increased Thyroidal Activity on Routine FDG-PET/CT after Combination Immune Checkpoint Inhibition: Temporal Associations with Clinical and Biochemical Thyroiditis

Severe acute respiratory syndrome coronavirus 2 as a potential cause of type 1 diabetes facilitated by spike protein receptor binding domain attachment to human islet cells: An illustrative case study and experimental data

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