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Anti–IL-5 (mepolizumab) therapy induces bone marrow eosinophil maturational arrest and decreases eosinophil progenitors in the bronchial mucosa of atopic asthmatics

Journal of allergy and clinical immunology, 2003-04, Vol.111 (4), p.714-719

2003

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Basophils, eosinophils, and mast cells in atopic and nonatopic asthma and in late-phase allergic reactions in the lung and skin

Journal of allergy and clinical immunology, 2000-01, Vol.105 (1), p.99-107

2000

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The role of T lymphocytes in the pathogenesis of asthma

Journal of allergy and clinical immunology, 2003-03, Vol.111 (3), p.450-463

2003

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TH1/TH2 cytokines and inflammatory cells in skin biopsy specimens from patients with chronic idiopathic urticaria: Comparison with the allergen-induced late-phase cutaneous reaction

Journal of allergy and clinical immunology, 2002-04, Vol.109 (4), p.694-700

2002

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Local expression of ε germline gene transcripts and RNA for the ε heavy chain of IgE in the bronchial mucosa in atopic and nonatopic asthma

Journal of allergy and clinical immunology, 2001-04, Vol.107 (4), p.686-692

2001

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Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma

Journal of allergy and clinical immunology, 1997-05, Vol.99 (5), p.657-665

1997

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Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-γ

Journal of allergy and clinical immunology, 1996-06, Vol.97 (6), p.1356-1365

1996

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The immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: more similarities than differences

Immunology Today, 1999-11, Vol.20 (11), p.528-533

1999

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Late asthmatic reactions provoked by intradermal injection of T-cell peptide epitopes are not associated with bronchial mucosal infiltration of eosinophils or TH2-type cells or with elevated concentrations of histamine or eicosanoids in bronchoalveolar fluid

Journal of allergy and clinical immunology, 2001-09, Vol.108 (3), p.394-401

2001

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Expression of high-affinity IgE receptors (FcϵRI) on peripheral blood basophils, monocytes, and eosinophils in atopic and nonatopic subjects: Relationship to total serum IgE concentrations

Journal of allergy and clinical immunology, 1997-05, Vol.99 (5), p.699-706

1997

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IL-5 secretion by allergen-stimulated CD4+ T cells in primary culture: Relationship to expression of allergic disease

Journal of allergy and clinical immunology, 1997-04, Vol.99 (4), p.563-569

1997

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Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: Comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness

Journal of allergy and clinical immunology, 1991-10, Vol.88 (4), p.661-674

1991

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Relationships among numbers of bronchoalveolar lavage cells expressing messenger ribonucleic acid for cytokines, asthma symptoms, and airway methacholine responsiveness in atopic asthma

Journal of allergy and clinical immunology, 1993-09, Vol.92 (3), p.397-403

1993

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Cytokine generation by eosinophils

Journal of allergy and clinical immunology, 1994-12, Vol.94 (6), p.1183-1188

1994

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IL-4– and IL-5–positive T lymphocytes, eosinophils, and mast cells in allergen-induced late-phase cutaneous reactions in atopic subjects

Journal of allergy and clinical immunology, 1998-02, Vol.101 (2), p.222-230

1998

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Expression of endothelial and leukocyte adhesion molecules intercellular adhesion molecule-1, E-selectin, and vascular cell adhesion molecule-1 in the bronchial mucosa in steady-state and allergen-induced asthma

Journal of allergy and clinical immunology, 1993-12, Vol.92 (6), p.857-868

1993

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Proliferation and release of IL-5 and IFN-γ by peripheral blood mononuclear cells from cat-allergic asthmatics and rhinitics, non–cat-allergic asthmatics, and normal controls to peptides derived from Fel d 1 chain 1

Journal of allergy and clinical immunology, 2001-09, Vol.108 (3), p.349-356

2001

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Enhanced expression of high-affinity IgE receptor (FcϵRI) α chain in human allergen-induced rhinitis with co-localization to mast cells, macrophages, eosinophils, and dendritic cells

Journal of allergy and clinical immunology, 1997-07, Vol.100 (1), p.78-86

1997

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Expression of the IL-4 receptor α-subunit is increased in bronchial biopsy specimens from atopic and nonatopic asthmatic subjects

Journal of allergy and clinical immunology, 1998-11, Vol.102 (5), p.859-866

1998

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Immunohistology of the nasal mucosa in seasonal allergic rhinitis: Increases in activated eosinophils and epithelial mast cells

Journal of allergy and clinical immunology, 1992-04, Vol.89 (4), p.877-883

1992

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Nasal eosinophilia and IL-5 mRNA expression in seasonal allergic rhinitis induced by natural allergen exposure: Effect of topical corticosteroids

Journal of allergy and clinical immunology, 1998-10, Vol.102 (4), p.610-617

1998

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Blood eosinophils from atopic donors express messenger RNA for the α, β, and γ subunits of the high-affinity IgE receptor (FcϵRI) and intracellular, but not cell surface, α subunit protein

Journal of allergy and clinical immunology, 2000-02, Vol.105 (2), p.309-317

2000

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Activated T-lymphocytes and eosinophils in the bronchial mucosa in isocyanate-induced asthma

Journal of allergy and clinical immunology, 1992-04, Vol.89 (4), p.821-829

1992

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Increased mature and immature CCR3 messenger RNA+ eosinophils in bone marrow from patients with atopic asthma compared with atopic and nonatopic control subjects

Journal of allergy and clinical immunology, 1999, Vol.103 (1), p.99-106

1999

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IL-3, IL-5, granulocyte-macrophage colony- stimulating factor receptor α-subunit, and common β-subunit expression by peripheral leukocytes and blood dendritic cells

Journal of allergy and clinical immunology, 1998-05, Vol.101 (5), p.677-682

1998

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Anti–IL-5 (mepolizumab) therapy induces bone marrow eosinophil maturational arrest and decreases eosinophil progenitors in the bronchial mucosa of atopic asthmatics

Basophils, eosinophils, and mast cells in atopic and nonatopic asthma and in late-phase allergic reactions in the lung and skin

The role of T lymphocytes in the pathogenesis of asthma

TH1/TH2 cytokines and inflammatory cells in skin biopsy specimens from patients with chronic idiopathic urticaria: Comparison with the allergen-induced late-phase cutaneous reaction

Local expression of ε germline gene transcripts and RNA for the ε heavy chain of IgE in the bronchial mucosa in atopic and nonatopic asthma

Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma

Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-γ

The immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: more similarities than differences

Late asthmatic reactions provoked by intradermal injection of T-cell peptide epitopes are not associated with bronchial mucosal infiltration of eosinophils or TH2-type cells or with elevated concentrations of histamine or eicosanoids in bronchoalveolar fluid

Expression of high-affinity IgE receptors (FcϵRI) on peripheral blood basophils, monocytes, and eosinophils in atopic and nonatopic subjects: Relationship to total serum IgE concentrations

IL-5 secretion by allergen-stimulated CD4+ T cells in primary culture: Relationship to expression of allergic disease

Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: Comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness

Relationships among numbers of bronchoalveolar lavage cells expressing messenger ribonucleic acid for cytokines, asthma symptoms, and airway methacholine responsiveness in atopic asthma

Cytokine generation by eosinophils

IL-4– and IL-5–positive T lymphocytes, eosinophils, and mast cells in allergen-induced late-phase cutaneous reactions in atopic subjects

Expression of endothelial and leukocyte adhesion molecules intercellular adhesion molecule-1, E-selectin, and vascular cell adhesion molecule-1 in the bronchial mucosa in steady-state and allergen-induced asthma

Proliferation and release of IL-5 and IFN-γ by peripheral blood mononuclear cells from cat-allergic asthmatics and rhinitics, non–cat-allergic asthmatics, and normal controls to peptides derived from Fel d 1 chain 1

Enhanced expression of high-affinity IgE receptor (FcϵRI) α chain in human allergen-induced rhinitis with co-localization to mast cells, macrophages, eosinophils, and dendritic cells

Expression of the IL-4 receptor α-subunit is increased in bronchial biopsy specimens from atopic and nonatopic asthmatic subjects

Immunohistology of the nasal mucosa in seasonal allergic rhinitis: Increases in activated eosinophils and epithelial mast cells

Nasal eosinophilia and IL-5 mRNA expression in seasonal allergic rhinitis induced by natural allergen exposure: Effect of topical corticosteroids

Blood eosinophils from atopic donors express messenger RNA for the α, β, and γ subunits of the high-affinity IgE receptor (FcϵRI) and intracellular, but not cell surface, α subunit protein

Activated T-lymphocytes and eosinophils in the bronchial mucosa in isocyanate-induced asthma

Increased mature and immature CCR3 messenger RNA+ eosinophils in bone marrow from patients with atopic asthma compared with atopic and nonatopic control subjects

IL-3, IL-5, granulocyte-macrophage colony- stimulating factor receptor α-subunit, and common β-subunit expression by peripheral leukocytes and blood dendritic cells

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