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The mechanisms and roles of selective autophagy in mammals

Nature reviews. Molecular cell biology, 2023-03, Vol.24 (3), p.167-185

2023

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Autophagosome biogenesis and human health

Cell discovery, 2020-06, Vol.6 (1), p.33-33, Article 33

2020

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Suppression of autophagic activity by Rubicon is a signature of aging

Nature communications, 2019-02, Vol.10 (1), p.847-11, Article 847

2019

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Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy

Nature communications, 2020-08, Vol.11 (1), p.4150-4150, Article 4150

2020

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Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice

Hepatology (Baltimore, Md.), 2016-12, Vol.64 (6), p.1994-2014

2016

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Nicaraven Attenuates Postoperative Systemic Inflammatory Responses-Induced Tumor Metastasis

Annals of surgical oncology, 2020-04, Vol.27 (4), p.1068-1074

2020

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Chronic replication stress invokes mitochondria dysfunction via impaired parkin activity

Scientific reports, 2024-04, Vol.14 (1), p.7877-7877, Article 7877

2024

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Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense

Nature immunology, 2017-08, Vol.18 (8), p.899-910

2017

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Deregulated MTOR (mechanistic target of rapamycin kinase) is responsible for autophagy defects exacerbating kidney stone development

Autophagy, 2020-04, Vol.16 (4), p.709-723

2020

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Polη, a Y-family translesion synthesis polymerase, promotes cellular tolerance of Myc-induced replication stress

Journal of cell science, 2018-06, Vol.131 (12), p.jcs212183-jcs212183

2018

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Rubicon regulates A2E-induced autophagy impairment in the retinal pigment epithelium implicated in the pathology of age-related macular degeneration

Biochemical and biophysical research communications, 2021-04, Vol.551, p.148-154

2021

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Rubicon prevents autophagic degradation of GATA4 to promote Sertoli cell function

PLoS genetics, 2021-08, Vol.17 (8), p.e1009688-e1009688

2021

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Bacterial secretion system skews the fate of Legionella-containing vacuoles towards LC3-associated phagocytosis

Scientific reports, 2017-03, Vol.7 (1), p.44795-44795, Article 44795

2017

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Nicaraven induces programmed cell death by distinct mechanisms according to the expression levels of Bcl-2 and poly (ADP-ribose) glycohydrolase in cancer cells

Translational oncology, 2022-12, Vol.26, p.101548-101548, Article 101548

2022

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Enhanced Expression of ABCB1 and Nrf2 in CD133-Positive Cancer Stem Cells Associates with Doxorubicin Resistance

Stem cells international, 2020, Vol.2020 (2020), p.1-13

2020

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Nicaraven prevents the fast growth of inflamed tumors by an anti-inflammatory mechanism

Medical oncology (Northwood, London, England), 2022-01, Vol.39 (1), p.7-7, Article 7

2022

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Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes

PLoS pathogens, 2017-07, Vol.13 (7), p.e1006444-e1006444

2017

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A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression

Nucleic acids research, 2014-05, Vol.42 (9), p.5605-5615

2014

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Beyond starvation: An update on the autophagic machinery and its functions

Journal of molecular and cellular cardiology, 2016-06, Vol.95, p.2-10

2016

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Methods for the detection of genome instability derived from replication stress in primary mouse embryonic fibroblasts

Methods in molecular biology (Clifton, N.J.), 2014-01, Vol.1194, p.341

2014

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Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis

Autophagy, 2022-10, Vol.18 (10), p.2323-2332

2022

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Loss of RUBCN/rubicon in adipocytes mediates the upregulation of autophagy to promote the fasting response

Autophagy, 2022-11, Vol.18 (11), p.2686-2696

2022

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Neurosprora crassa RAD5 homologue, mus-41, inactivation results in higher sensitivity to mutagens but has little effect on PCNA-ubiquitylation in response to UV-irradiation

Current genetics, 2007-09, Vol.52 (3-4), p.125-135

2007

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Biphasic effect of mechanical stress on lymphocyte activation

Journal of cellular physiology, 2022-02, Vol.237 (2), p.1521-1531

2022

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Stalled Fork Rescue via Dormant Replication Origins in Unchallenged S Phase Promotes Proper Chromosome Segregation and Tumor Suppression

Molecular cell, 2011-03, Vol.41 (5), p.543-553

2011

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The mechanisms and roles of selective autophagy in mammals

Autophagosome biogenesis and human health

Suppression of autophagic activity by Rubicon is a signature of aging

Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy

Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice

Nicaraven Attenuates Postoperative Systemic Inflammatory Responses-Induced Tumor Metastasis

Chronic replication stress invokes mitochondria dysfunction via impaired parkin activity

Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense

Deregulated MTOR (mechanistic target of rapamycin kinase) is responsible for autophagy defects exacerbating kidney stone development

Polη, a Y-family translesion synthesis polymerase, promotes cellular tolerance of Myc-induced replication stress

Rubicon regulates A2E-induced autophagy impairment in the retinal pigment epithelium implicated in the pathology of age-related macular degeneration

Rubicon prevents autophagic degradation of GATA4 to promote Sertoli cell function

Bacterial secretion system skews the fate of Legionella-containing vacuoles towards LC3-associated phagocytosis

Nicaraven induces programmed cell death by distinct mechanisms according to the expression levels of Bcl-2 and poly (ADP-ribose) glycohydrolase in cancer cells

Enhanced Expression of ABCB1 and Nrf2 in CD133-Positive Cancer Stem Cells Associates with Doxorubicin Resistance

Nicaraven prevents the fast growth of inflamed tumors by an anti-inflammatory mechanism

Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes

A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression

Beyond starvation: An update on the autophagic machinery and its functions

Methods for the detection of genome instability derived from replication stress in primary mouse embryonic fibroblasts

Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis

Loss of RUBCN/rubicon in adipocytes mediates the upregulation of autophagy to promote the fasting response

Neurosprora crassa RAD5 homologue, mus-41, inactivation results in higher sensitivity to mutagens but has little effect on PCNA-ubiquitylation in response to UV-irradiation

Biphasic effect of mechanical stress on lymphocyte activation

Stalled Fork Rescue via Dormant Replication Origins in Unchallenged S Phase Promotes Proper Chromosome Segregation and Tumor Suppression

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