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Microglial NMDA receptors drive pro‐inflammatory responses via PARP‐1/TRMP2 signaling

Glia, 2020-07, Vol.68 (7), p.1421-1434

2020

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Microglial Activation in Stroke: Therapeutic Targets

Neurotherapeutics, 2010-10, Vol.7 (4), p.378-391

2010

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NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

Nature neuroscience, 2009-07, Vol.12 (7), p.857-863

2009

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CX3CR1 Protein Signaling Modulates Microglial Activation and Protects against Plaque-independent Cognitive Deficits in a Mouse Model of Alzheimer Disease

The Journal of biological chemistry, 2011-09, Vol.286 (37), p.32713-32722

2011

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Exposure to gestational diabetes mellitus induces neuroinflammation, derangement of hippocampal neurons, and cognitive changes in rat offspring

Journal of neuroinflammation, 2017-04, Vol.14 (1), p.80-80, Article 80

2017

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Cortical astrocyte N-methyl-D-aspartate receptors influence whisker barrel activity and sensory discrimination in mice

Nature communications, 2024-02, Vol.15 (1), p.1571-1571, Article 1571

2024

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Minocycline Inhibits Poly(ADP-Ribose) Polymerase-1 at Nanomolar Concentrations

Proceedings of the National Academy of Sciences - PNAS, 2006-06, Vol.103 (25), p.9685-9690

2006

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Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor

Journal of neuroinflammation, 2012-02, Vol.9 (1), p.31-31, Article 31

2012

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N-acetylcysteine prevents loss of dopaminergic neurons in the EAAC1−/− mouse

Annals of neurology, 2011-03, Vol.69 (3), p.509-520

2011

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Zinc Triggers Microglial Activation

The Journal of neuroscience, 2008-05, Vol.28 (22), p.5827-5835

2008

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Inhibition of NADPH oxidase activation reduces EAE-induced white matter damage in mice

Journal of neuroinflammation, 2015-05, Vol.12 (1), p.104-104, Article 104

2015

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Poly(ADP-Ribose) Polymerase-1 Promotes Microglial Activation, Proliferation, and Matrix Metalloproteinase-9-Mediated Neuron Death

The Journal of immunology (1950), 2005-02, Vol.174 (4), p.2288-2296

2005

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Recurrent/moderate hypoglycemia induces hippocampal dendritic injury, microglial activation, and cognitive impairment in diabetic rats

Journal of neuroinflammation, 2012-07, Vol.9 (1), p.182-182, Article 182

2012

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Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β

Journal of neuroinflammation, 2011-11, Vol.8 (1), p.152-152

2011

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Direct Phosphorylation and Regulation of Poly(ADP-Ribose) Polymerase-1 by Extracellular Signal-Regulated Kinases 1/2

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (18), p.7136-7141

2006

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PARP-DNA trapping ability of PARP inhibitors jeopardizes astrocyte viability: Implications for CNS disease therapeutics

Neuropharmacology, 2021-04, Vol.187, p.108502-108502, Article 108502

2021

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Use of a poly(ADP-ribose) polymerase inhibitor to suppress inflammation and neuronal death after cerebral ischemia-reperfusion

Stroke (1970), 2007-02, Vol.38 (2), p.632-636

2007

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EAAC1 gene deletion alters zinc homeostasis and exacerbates neuronal injury after transient cerebral ischemia

The Journal of neuroscience, 2010-11, Vol.30 (46), p.15409-15418

2010

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NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death

The Journal of neuroscience, 2010-02, Vol.30 (8), p.2967-2978

2010

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Prevention of hypoglycemia-induced neuronal death by minocycline

Journal of neuroinflammation, 2012-09, Vol.9 (1), p.225-225, Article 225

2012

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Poly(ADP-ribose) polymerase-1-induced NAD+ depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation

Biochimica et biophysica acta, 2013-08, Vol.1833 (8), p.1985-1991

2013

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Selective down-regulation of nuclear poly(ADP-ribose) glycohydrolase

PloS one, 2009-03, Vol.4 (3), p.e4896-e4896

2009

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Prevention of hypoglycemia-induced neuronal death by hypothermia

Journal of cerebral blood flow and metabolism, 2010-02, Vol.30 (2), p.390-402

2010

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Poly(ADP-ribose) polymerase-1 regulates microglia mediated decrease of endothelial tight junction integrity

Neurochemistry international, 2017-09, Vol.108, p.266-271

2017

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Astrocyte influences on ischemic neuronal death

Current molecular medicine, 2004-03, Vol.4 (2), p.193-205

2004

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Microglial NMDA receptors drive pro‐inflammatory responses via PARP‐1/TRMP2 signaling

Microglial Activation in Stroke: Therapeutic Targets

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

CX3CR1 Protein Signaling Modulates Microglial Activation and Protects against Plaque-independent Cognitive Deficits in a Mouse Model of Alzheimer Disease

Exposure to gestational diabetes mellitus induces neuroinflammation, derangement of hippocampal neurons, and cognitive changes in rat offspring

Cortical astrocyte N-methyl-D-aspartate receptors influence whisker barrel activity and sensory discrimination in mice

Minocycline Inhibits Poly(ADP-Ribose) Polymerase-1 at Nanomolar Concentrations

Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor

N-acetylcysteine prevents loss of dopaminergic neurons in the EAAC1−/− mouse

Zinc Triggers Microglial Activation

Inhibition of NADPH oxidase activation reduces EAE-induced white matter damage in mice

Poly(ADP-Ribose) Polymerase-1 Promotes Microglial Activation, Proliferation, and Matrix Metalloproteinase-9-Mediated Neuron Death

Recurrent/moderate hypoglycemia induces hippocampal dendritic injury, microglial activation, and cognitive impairment in diabetic rats

Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β

Direct Phosphorylation and Regulation of Poly(ADP-Ribose) Polymerase-1 by Extracellular Signal-Regulated Kinases 1/2

PARP-DNA trapping ability of PARP inhibitors jeopardizes astrocyte viability: Implications for CNS disease therapeutics

Use of a poly(ADP-ribose) polymerase inhibitor to suppress inflammation and neuronal death after cerebral ischemia-reperfusion

EAAC1 gene deletion alters zinc homeostasis and exacerbates neuronal injury after transient cerebral ischemia

NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death

Prevention of hypoglycemia-induced neuronal death by minocycline

Poly(ADP-ribose) polymerase-1-induced NAD+ depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation

Selective down-regulation of nuclear poly(ADP-ribose) glycohydrolase

Prevention of hypoglycemia-induced neuronal death by hypothermia

Poly(ADP-ribose) polymerase-1 regulates microglia mediated decrease of endothelial tight junction integrity

Astrocyte influences on ischemic neuronal death

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