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The mitochondrial transcription factor TFAM in neurodegeneration: emerging evidence and mechanisms

FEBS letters, 2018-03, Vol.592 (5), p.793-811

2018

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Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis

Cell metabolism, 2019-10, Vol.30 (4), p.784-799.e5

2019

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Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number

Biochimica et biophysica acta, 2012-09, Vol.1819 (9-10), p.921-929

2012

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Reconstitution of mitochondria derived vesicle formation demonstrates selective enrichment of oxidized cargo

PloS one, 2012-12, Vol.7 (12), p.e52830-e52830

2012

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POLB: A new role of DNA polymerase beta in mitochondrial base excision repair

DNA repair, 2017-12, Vol.60, p.A1-A5

2017

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Stress and circulating cell-free mitochondrial DNA: A systematic review of human studies, physiological considerations, and technical recommendations

Mitochondrion, 2021-07, Vol.59, p.225-245

2021

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Potential Roles for G-Quadruplexes in Mitochondria

Current medicinal chemistry, 2019-01, Vol.26 (16), p.2918-2932

2019

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Mitofusin 1 and 2 regulation of mitochondrial DNA content is a critical determinant of glucose homeostasis

Nature communications, 2022-04, Vol.13 (1), p.2340-16, Article 2340

2022

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PINK1 attenuates mtDNA release in alveolar epithelial cells and TLR9 mediated profibrotic responses

PloS one, 2019-06, Vol.14 (6), p.e0218003-e0218003

2019

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LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson's disease

Human molecular genetics, 2017-11, Vol.26 (22), p.4340-4351

2017

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The Diabetes Susceptibility Gene Clec16a Regulates Mitophagy

Cell, 2014-06, Vol.157 (7), p.1577-1590

2014

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Mutation in TACO1 , encoding a translational activator of COX I, results in cytochrome c oxidase deficiency and late-onset Leigh syndrome

Nature genetics, 2009-07, Vol.41 (7), p.833-837

2009

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A novel ultrasound-guided mouse model of sudden cardiac arrest

PloS one, 2020-12, Vol.15 (12), p.e0237292

2020

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Small molecule-mediated allosteric activation of the base excision repair enzyme 8-oxoguanine DNA glycosylase and its impact on mitochondrial function

Scientific reports, 2022-08, Vol.12 (1), p.14685-14685, Article 14685

2022

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Digital PCR methods improve detection sensitivity and measurement precision of low abundance mtDNA deletions

Scientific reports, 2016-04, Vol.6 (1), p.25186-25186, Article 25186

2016

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Cell-free DNA levels associate with COPD exacerbations and mortality

Respiratory research, 2024-01, Vol.25 (1), p.42-42, Article 42

2024

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Loss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death

The Journal of clinical investigation, 2022-09, Vol.132 (18), p.1-16

2022

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G-quadruplex-mediated reduction of a pathogenic mitochondrial heteroplasmy

Human molecular genetics, 2019-10, Vol.28 (19), p.3163-3174

2019

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Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice

Free radical biology & medicine, 2014-10, Vol.75, p.241-251

2014

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Nox1/Ref-1-mediated activation of CREB promotes Gremlin1-driven endothelial cell proliferation and migration

Redox biology, 2019-04, Vol.22, p.101138-101138, Article 101138

2019

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Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance

Molecular metabolism (Germany), 2020-11, Vol.41, p.101051-101051, Article 101051

2020

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A murine model of the human CREBRFR457Q obesity-risk variant does not influence energy or glucose homeostasis in response to nutritional stress

PloS one, 2021-09, Vol.16 (9), p.e0251895

2021

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OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases

Communications biology, 2023-01, Vol.6 (1), p.22-22, Article 22

2023

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Aconitase couples metabolic regulation to mitochondrial DNA maintenance

Science (American Association for the Advancement of Science), 2005-02, Vol.307 (5710), p.714-717

2005

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Extracellular Release of Mitochondrial DNA: Triggered by Cigarette Smoke and Detected in COPD

Cells (Basel, Switzerland), 2022-01, Vol.11 (3), p.369

2022

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The mitochondrial transcription factor TFAM in neurodegeneration: emerging evidence and mechanisms

Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis

Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number

Reconstitution of mitochondria derived vesicle formation demonstrates selective enrichment of oxidized cargo

POLB: A new role of DNA polymerase beta in mitochondrial base excision repair

Stress and circulating cell-free mitochondrial DNA: A systematic review of human studies, physiological considerations, and technical recommendations

Potential Roles for G-Quadruplexes in Mitochondria

Mitofusin 1 and 2 regulation of mitochondrial DNA content is a critical determinant of glucose homeostasis

PINK1 attenuates mtDNA release in alveolar epithelial cells and TLR9 mediated profibrotic responses

LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson's disease

The Diabetes Susceptibility Gene Clec16a Regulates Mitophagy

Mutation in TACO1 , encoding a translational activator of COX I, results in cytochrome c oxidase deficiency and late-onset Leigh syndrome

A novel ultrasound-guided mouse model of sudden cardiac arrest

Small molecule-mediated allosteric activation of the base excision repair enzyme 8-oxoguanine DNA glycosylase and its impact on mitochondrial function

Digital PCR methods improve detection sensitivity and measurement precision of low abundance mtDNA deletions

Cell-free DNA levels associate with COPD exacerbations and mortality

Loss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death

G-quadruplex-mediated reduction of a pathogenic mitochondrial heteroplasmy

Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice

Nox1/Ref-1-mediated activation of CREB promotes Gremlin1-driven endothelial cell proliferation and migration

Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance

A murine model of the human CREBRFR457Q obesity-risk variant does not influence energy or glucose homeostasis in response to nutritional stress

OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases

Aconitase couples metabolic regulation to mitochondrial DNA maintenance

Extracellular Release of Mitochondrial DNA: Triggered by Cigarette Smoke and Detected in COPD

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