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Phospholipid Transfer Protein Is Regulated by Liver X Receptors in Vivo

The Journal of biological chemistry, 2002-10, Vol.277 (42), p.39561-39565

2002

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Raloxifene inhibits aortic accumulation of cholesterol in ovariectomized, cholesterol-fed rabbits

Circulation (New York, N.Y.), 1997-09, Vol.96 (6), p.1964-1969

1997

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Cholesteryl ester transfer protein expression prevents diet-induced atherosclerotic lesions in male db/db mice

Arteriosclerosis, thrombosis, and vascular biology, 2003-08, Vol.23 (8), p.1412-1415

2003

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Peroxisome proliferator-activated receptor subtype-specific regulation of hepatic and peripheral gene expression in the zucker diabetic fatty rat

Metabolism, clinical and experimental, 2001-08, Vol.50 (8), p.963-971

2001

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Design and Synthesis of a Potent and Selective Triazolone-Based Peroxisome Proliferator-Activated Receptor α Agonist

Journal of medicinal chemistry, 2003-11, Vol.46 (24), p.5121-5124

2003

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Coadministration of a liver X receptor agonist and a peroxisome proliferator activator receptor-alpha agonist in Mice: effects of nuclear receptor interplay on high-density lipoprotein and triglyceride metabolism in vivo

The Journal of pharmacology and experimental therapeutics, 2004-06, Vol.309 (3), p.861-868

2004

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Design and Synthesis of 2-Methyl-2-{4-[2-(5-methyl-2-aryloxazol- 4-yl)ethoxy]phenoxy}propionic Acids: A New Class of Dual PPARα/γ Agonists

Journal of medicinal chemistry, 2001-06, Vol.44 (13), p.2061-2064

2001

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Peroxisome proliferator‐activated receptor α,γ coagonist LY465608 inhibits macrophage activation and atherosclerosis in apolipoprotein E knockout mice

Lipids, 2002-05, Vol.37 (5), p.487-494

2002

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Raloxifene and estrogen reduces progression of advanced atherosclerosis — a study in ovariectomized, cholesterol-fed rabbits

Atherosclerosis, 2001, Vol.154 (1), p.97-102

2001

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Identification and Characterization of Hamster Stearoyl-CoA Desaturase Isoforms

Lipids, 2008-03, Vol.43 (3), p.197-205

2008

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Rosiglitazone treatment improves insulin regulation and dyslipidemia in type 2 diabetic cynomolgus monkeys

Metabolism, clinical and experimental, 2004-09, Vol.53 (9), p.1121-1125

2004

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Raloxifene reduces atherosclerosis: studies of optimized raloxifene doses in ovariectomized, cholesterol-fed rabbits

Clinical endocrinology (Oxford), 2000-02, Vol.52 (2), p.225-233

2000

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Dihydropyridazinone cardiotonics: synthesis and inotropic activity of 5'-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-spiro[cycloalkane-1,3'-[3H]indol]-2'(1'H)-ones

Journal of medicinal chemistry, 1987-05, Vol.30 (5), p.824-829

1987

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Dihydropyridazinone cardiotonics. The discovery and inotropic activity of 1,3-dihydro-3,3-dimethyl-5-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-2H-indol-2-one

Journal of medicinal chemistry, 1986-10, Vol.29 (10), p.1832-1840

1986

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Conversion of human-selective PPARα agonists to human/mouse dual agonists: a molecular modeling analysis

Bioorganic & medicinal chemistry letters, 2004-12, Vol.14 (24), p.6113-6116

2004

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Losartan, a nonpeptide angiotensin II (Ang II) receptor antagonist, inhibits neointima formation following balloon injury to rat carotid arteries

Life sciences (1973), 1991, Vol.49 (25), p.PL223-PL228

1991

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Hypocholesterolemic activity of raloxifene (LY139481): pharmacological characterization as a selective estrogen receptor modulator

The Journal of pharmacology and experimental therapeutics, 1997-01, Vol.280 (1), p.146

1997

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Raloxifene and Estrogen Inhibit Neointimal Thickening After Balloon Injury in the Carotid Artery of Male and Ovariectomized Female Rats

Journal of cardiovascular pharmacology, 2000-10, Vol.36 (4), p.459-465

2000

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Comment on Lack of Effect of Raloxifene on Coronary Artery Atherosclerosis of Postmenopausal Monkeys

The journal of clinical endocrinology and metabolism, 1998-08, Vol.83 (8), p.3001-a-3002

1998

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Effects of LY295427, a low-density lipoprotein (LDL) receptor up-regulator, on LDL receptor gene transcription and cholesterol metabolism in normal and hypercholesterolemic hamsters

The Journal of pharmacology and experimental therapeutics, 1999-04, Vol.289 (1), p.85

1999

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Raloxifene (LY139481 HCl) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats

The Journal of clinical investigation, 1994, Vol.93 (1), p.63-69

1994

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A Tailored Therapy for the Metabolic Syndrome

Diabetes (New York, N.Y.), 2002-04, Vol.51 (4), p.1083-1087

2002

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Synthesis and Biological Evaluation of a New Series of Sterols as Potential Hypocholesterolemic Agents

Journal of medicinal chemistry, 1995-01, Vol.38 (2), p.277-288

1995

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Design and Synthesis of α-Aryloxy-α-methylhydrocinnamic Acids: A Novel Class of Dual Peroxisome Proliferator-Activated Receptor α/γ Agonists

Journal of medicinal chemistry, 2004-05, Vol.47 (10), p.2422-2425

2004

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Phospholipid Transfer Protein Is Regulated by Liver X Receptors in Vivo

Raloxifene inhibits aortic accumulation of cholesterol in ovariectomized, cholesterol-fed rabbits

Cholesteryl ester transfer protein expression prevents diet-induced atherosclerotic lesions in male db/db mice

Peroxisome proliferator-activated receptor subtype-specific regulation of hepatic and peripheral gene expression in the zucker diabetic fatty rat

Design and Synthesis of a Potent and Selective Triazolone-Based Peroxisome Proliferator-Activated Receptor α Agonist

A tailored therapy for the metabolic syndrome: The dual peroxisome proliferator-activated receptor-α/γ agonist LY465608 ameliorates insulin resistance and diabetic hyperglycemia while improving cardiovascular risk factors in preclinical models

Coadministration of a liver X receptor agonist and a peroxisome proliferator activator receptor-alpha agonist in Mice: effects of nuclear receptor interplay on high-density lipoprotein and triglyceride metabolism in vivo

Design and Synthesis of 2-Methyl-2-{4-[2-(5-methyl-2-aryloxazol- 4-yl)ethoxy]phenoxy}propionic Acids: A New Class of Dual PPARα/γ Agonists

Peroxisome proliferator‐activated receptor α,γ coagonist LY465608 inhibits macrophage activation and atherosclerosis in apolipoprotein E knockout mice

Raloxifene and estrogen reduces progression of advanced atherosclerosis — a study in ovariectomized, cholesterol-fed rabbits

Identification and Characterization of Hamster Stearoyl-CoA Desaturase Isoforms

Rosiglitazone treatment improves insulin regulation and dyslipidemia in type 2 diabetic cynomolgus monkeys

Raloxifene reduces atherosclerosis: studies of optimized raloxifene doses in ovariectomized, cholesterol-fed rabbits

Dihydropyridazinone cardiotonics: synthesis and inotropic activity of 5'-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-spiro[cycloalkane-1,3'-[3H]indol]-2'(1'H)-ones

Dihydropyridazinone cardiotonics. The discovery and inotropic activity of 1,3-dihydro-3,3-dimethyl-5-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-2H-indol-2-one

Conversion of human-selective PPARα agonists to human/mouse dual agonists: a molecular modeling analysis

Losartan, a nonpeptide angiotensin II (Ang II) receptor antagonist, inhibits neointima formation following balloon injury to rat carotid arteries

Hypocholesterolemic activity of raloxifene (LY139481): pharmacological characterization as a selective estrogen receptor modulator

Raloxifene and Estrogen Inhibit Neointimal Thickening After Balloon Injury in the Carotid Artery of Male and Ovariectomized Female Rats

Comment on Lack of Effect of Raloxifene on Coronary Artery Atherosclerosis of Postmenopausal Monkeys

Effects of LY295427, a low-density lipoprotein (LDL) receptor up-regulator, on LDL receptor gene transcription and cholesterol metabolism in normal and hypercholesterolemic hamsters

Raloxifene (LY139481 HCl) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats

A Tailored Therapy for the Metabolic Syndrome

Synthesis and Biological Evaluation of a New Series of Sterols as Potential Hypocholesterolemic Agents

Design and Synthesis of α-Aryloxy-α-methylhydrocinnamic Acids: A Novel Class of Dual Peroxisome Proliferator-Activated Receptor α/γ Agonists

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