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Raloxifene inhibits aortic accumulation of cholesterol in ovariectomized, cholesterol-fed rabbits

Circulation (New York, N.Y.), 1997-09, Vol.96 (6), p.1964-1969

1997

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Raloxifene (LY139481 HCl) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats

The Journal of clinical investigation, 1994, Vol.93 (1), p.63-69

1994

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Phospholipid Transfer Protein Is Regulated by Liver X Receptors in Vivo

The Journal of biological chemistry, 2002-10, Vol.277 (42), p.39561-39565

2002

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Raloxifene reduces atherosclerosis: studies of optimized raloxifene doses in ovariectomized, cholesterol-fed rabbits

Clinical endocrinology (Oxford), 2000-02, Vol.52 (2), p.225-233

2000

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LY195115: a potent, selective inhibitor of cyclic nucleotide phosphodiesterase located in the sarcoplasmic reticulum

Molecular pharmacology, 1986-12, Vol.30 (6), p.609-616

1986

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Inhibition of cholesteryl ester transfer protein in normocholesterolemic and hypercholesterolemic hamsters: effects on HDL subspecies, quantity, and apolipoprotein distribution

Journal of lipid research, 1994-09, Vol.35 (9), p.1634-1645

1994

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Cholesteryl ester transfer protein expression prevents diet-induced atherosclerotic lesions in male db/db mice

Arteriosclerosis, thrombosis, and vascular biology, 2003-08, Vol.23 (8), p.1412-1415

2003

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Design and Synthesis of 2-Methyl-2-{4-[2-(5-methyl-2-aryloxazol- 4-yl)ethoxy]phenoxy}propionic Acids: A New Class of Dual PPARα/γ Agonists

Journal of medicinal chemistry, 2001-06, Vol.44 (13), p.2061-2064

2001

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In vitro vascular relaxation by new inotropic agents: relationship to phosphodiesterase inhibition and cyclic nucleotides

The Journal of pharmacology and experimental therapeutics, 1987-09, Vol.242 (3), p.864

1987

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Inhibition of vascular smooth muscle cell proliferation and arterial intimal thickening by a novel antiproliferative naphthopyran

The Journal of pharmacology and experimental therapeutics, 1996-09, Vol.278 (3), p.1452

1996

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Peroxisome proliferator-activated receptor subtype-specific regulation of hepatic and peripheral gene expression in the zucker diabetic fatty rat

Metabolism, clinical and experimental, 2001-08, Vol.50 (8), p.963-971

2001

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Raloxifene and estrogen reduces progression of advanced atherosclerosis — a study in ovariectomized, cholesterol-fed rabbits

Atherosclerosis, 2001, Vol.154 (1), p.97-102

2001

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Synthesis and Biological Evaluation of a New Series of Sterols as Potential Hypocholesterolemic Agents

Journal of medicinal chemistry, 1995-01, Vol.38 (2), p.277-288

1995

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Characterization and Pharmacological Relevance of High Affinity Binding Sites for [3H]LY186126, a Cardiotonic Phosphodiesterase Inhibitor, in Canine Cardiac Membranes

Circulation research, 1989-07, Vol.65 (1), p.154-163

1989

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Vascular serotonin 5-hydroxytryptamine2 receptor blockade by LY215840: lack of effect upon neointima formation in balloon-injured rat carotid arteries

The Journal of pharmacology and experimental therapeutics, 1993-07, Vol.266 (1), p.450

1993

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Cation transport and specificity of ionomycin. Comparison with ionophore A23187 in rat liver mitochondria

The Journal of biological chemistry, 1980-04, Vol.255 (7), p.2735-2739

1980

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Dihydropyridazinone cardiotonics. The discovery and inotropic activity of 1,3-dihydro-3,3-dimethyl-5-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-2H-indol-2-one

Journal of medicinal chemistry, 1986-10, Vol.29 (10), p.1832-1840

1986

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Hypocholesterolemic activity of raloxifene (LY139481): pharmacological characterization as a selective estrogen receptor modulator

The Journal of pharmacology and experimental therapeutics, 1997-01, Vol.280 (1), p.146

1997

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Raloxifene and Estrogen Inhibit Neointimal Thickening After Balloon Injury in the Carotid Artery of Male and Ovariectomized Female Rats

Journal of cardiovascular pharmacology, 2000-10, Vol.36 (4), p.459-465

2000

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Losartan, a nonpeptide angiotensin II (Ang II) receptor antagonist, inhibits neointima formation following balloon injury to rat carotid arteries

Life sciences (1973), 1991, Vol.49 (25), p.PL223-PL228

1991

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Synthesis of a tritium-labeled indolidan analog and its use as a radioligand for phosphodiesterase-inhibitor cardiotonic binding sites

Journal of medicinal chemistry, 1989-07, Vol.32 (7), p.1476-1480

1989

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Specific Binding of [3H]LY186126, an Analogue of Indolidan (LY195115), to Cardiac Membranes Enriched in Sarcoplasmic Reticulum Vesicles

Circulation research, 1989-05, Vol.64 (5), p.1037-1040

1989

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Effects of LY295427, a low-density lipoprotein (LDL) receptor up-regulator, on LDL receptor gene transcription and cholesterol metabolism in normal and hypercholesterolemic hamsters

The Journal of pharmacology and experimental therapeutics, 1999-04, Vol.289 (1), p.85

1999

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Molecular basis for the in vitro and in vivo cardiotonic activities of AR-L100

The Journal of pharmacology and experimental therapeutics, 1986-11, Vol.239 (2), p.375

1986

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Comment on Lack of Effect of Raloxifene on Coronary Artery Atherosclerosis of Postmenopausal Monkeys

The journal of clinical endocrinology and metabolism, 1998-08, Vol.83 (8), p.3001-a-3002

1998

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Raloxifene inhibits aortic accumulation of cholesterol in ovariectomized, cholesterol-fed rabbits

Raloxifene (LY139481 HCl) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats

Phospholipid Transfer Protein Is Regulated by Liver X Receptors in Vivo

Raloxifene reduces atherosclerosis: studies of optimized raloxifene doses in ovariectomized, cholesterol-fed rabbits

LY195115: a potent, selective inhibitor of cyclic nucleotide phosphodiesterase located in the sarcoplasmic reticulum

Inhibition of cholesteryl ester transfer protein in normocholesterolemic and hypercholesterolemic hamsters: effects on HDL subspecies, quantity, and apolipoprotein distribution

Cholesteryl ester transfer protein expression prevents diet-induced atherosclerotic lesions in male db/db mice

Design and Synthesis of 2-Methyl-2-{4-[2-(5-methyl-2-aryloxazol- 4-yl)ethoxy]phenoxy}propionic Acids: A New Class of Dual PPARα/γ Agonists

In vitro vascular relaxation by new inotropic agents: relationship to phosphodiesterase inhibition and cyclic nucleotides

Inhibition of vascular smooth muscle cell proliferation and arterial intimal thickening by a novel antiproliferative naphthopyran

Peroxisome proliferator-activated receptor subtype-specific regulation of hepatic and peripheral gene expression in the zucker diabetic fatty rat

Raloxifene and estrogen reduces progression of advanced atherosclerosis — a study in ovariectomized, cholesterol-fed rabbits

Synthesis and Biological Evaluation of a New Series of Sterols as Potential Hypocholesterolemic Agents

Characterization and Pharmacological Relevance of High Affinity Binding Sites for [3H]LY186126, a Cardiotonic Phosphodiesterase Inhibitor, in Canine Cardiac Membranes

Vascular serotonin 5-hydroxytryptamine2 receptor blockade by LY215840: lack of effect upon neointima formation in balloon-injured rat carotid arteries

Cation transport and specificity of ionomycin. Comparison with ionophore A23187 in rat liver mitochondria

Dihydropyridazinone cardiotonics. The discovery and inotropic activity of 1,3-dihydro-3,3-dimethyl-5-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-2H-indol-2-one

Hypocholesterolemic activity of raloxifene (LY139481): pharmacological characterization as a selective estrogen receptor modulator

Raloxifene and Estrogen Inhibit Neointimal Thickening After Balloon Injury in the Carotid Artery of Male and Ovariectomized Female Rats

Losartan, a nonpeptide angiotensin II (Ang II) receptor antagonist, inhibits neointima formation following balloon injury to rat carotid arteries

Synthesis of a tritium-labeled indolidan analog and its use as a radioligand for phosphodiesterase-inhibitor cardiotonic binding sites

Specific Binding of [3H]LY186126, an Analogue of Indolidan (LY195115), to Cardiac Membranes Enriched in Sarcoplasmic Reticulum Vesicles

Effects of LY295427, a low-density lipoprotein (LDL) receptor up-regulator, on LDL receptor gene transcription and cholesterol metabolism in normal and hypercholesterolemic hamsters

Molecular basis for the in vitro and in vivo cardiotonic activities of AR-L100

Comment on Lack of Effect of Raloxifene on Coronary Artery Atherosclerosis of Postmenopausal Monkeys

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