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Expression, Crystallization, and Three-dimensional Structure of the Catalytic Domain of Human Plasma Kallikrein

The Journal of biological chemistry, 2005-12, Vol.280 (49), p.41077-41089

2005

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Development of Serine Protease Inhibitors Displaying a Multicentered Short (<2.3 Å) Hydrogen Bond Binding Mode: Inhibitors of Urokinase-Type Plasminogen Activator and Factor Xa

Journal of medicinal chemistry, 2001-08, Vol.44 (17), p.2753-2771

2001

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The Structure of the Extracellular Region of Human Hepsin Reveals a Serine Protease Domain and a Novel Scavenger Receptor Cysteine-Rich (SRCR) Domain

Structure (London), 2003-09, Vol.11 (9), p.1123-1131

2003

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Binding to Protein Targets of Peptidic Leads Discovered by Phage Display: Crystal Structures of Streptavidin-Bound Linear and Cyclic Peptide Ligands Containing the HPQ Sequence

Biochemistry (Easton), 1995-11, Vol.34 (47), p.15421-15429

Katz, Bradley A

1995

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Design of potent selective zinc-mediated serine protease inhibitors

Nature (London), 1998-02, Vol.391 (6667), p.608-612

1998

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Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH

Journal of molecular biology, 1997-12, Vol.274 (5), p.776-800

Katz, Bradley A

1997

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Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases

Structure (London), 2004-07, Vol.12 (7), p.1325-1334

2004

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Discovery of novel heterocyclic factor VIIa inhibitors

Bioorganic & medicinal chemistry letters, 2006-04, Vol.16 (8), p.2270-2273

2006

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Factor VIIa inhibitors: Chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in an arterial baboon thrombosis model

Bioorganic & medicinal chemistry letters, 2006-04, Vol.16 (7), p.2037-2041

2006

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Efficiency of signalling through cytokine receptors depends critically on receptor orientation

Nature (London), 1998-10, Vol.395 (6701), p.511-516

1998

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Exploiting Subsite S1 of Trypsin-Like Serine Proteases for Selectivity: Potent and Selective Inhibitors of Urokinase-Type Plasminogen Activator

Journal of medicinal chemistry, 2001-11, Vol.44 (23), p.3856-3871

2001

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Promoter polymorphism of the erythropoietin gene in severe diabetic eye and kidney complications

Proceedings of the National Academy of Sciences - PNAS, 2008-05, Vol.105 (19), p.6998-7003

2008

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Peripapillary Ovoid Hyperreflectivity in Optic Disc Edema and Pseudopapilledema

Ophthalmology (Rochester, Minn.), 2018-10, Vol.125 (10), p.1662-1664

2018

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A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site

Journal of molecular biology, 2001-04, Vol.307 (5), p.1451-1486

2001

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Update on blepharospasm: report from the BEBRF International Workshop

Neurology, 2008-10, Vol.71 (16), p.1275-1282

2008

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Structure-Guided Design of Peptide-Based Tryptase Inhibitors

Biochemistry (Easton), 2006-05, Vol.45 (19), p.5964-5973

2006

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Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-directed Serine Protease Inhibitors

Journal of molecular biology, 2003-05, Vol.329 (1), p.93-120

2003

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Factor VIIa inhibitors: Gaining selectivity within the trypsin family

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (6), p.1596-1600

2006

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The Idiopathic Intracranial Hypertension Treatment Trial: Design Considerations and Methods

Journal of neuro-ophthalmology, 2014-06, Vol.34 (2), p.107-117

2014

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Factor VIIa inhibitors: Improved pharmacokinetic parameters

Bioorganic & medicinal chemistry letters, 2006-04, Vol.16 (8), p.2243-2246

2006

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Contribution of Multicentered Short Hydrogen Bond Arrays to Potency of Active Site-Directed Serine Protease Inhibitors

Journal of the American Chemical Society, 2002-10, Vol.124 (39), p.11657-11668

2002

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Structure-based design of high affinity streptavidin binding cyclic peptide ligands containing thioether crosslinks

Journal of the American Chemical Society, 1995-08, Vol.117 (33), p.8541-8547

1995

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2-(2-Hydroxy-3-alkoxyphenyl)-1H-benzimidazole-5-carboxamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors

Bioorganic & medicinal chemistry letters, 2002-08, Vol.12 (15), p.2019-2022

2002

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4-Aminoarylguanidine and 4-aminobenzamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors

Bioorganic & medicinal chemistry letters, 2002-08, Vol.12 (15), p.2023-2026

2002

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A Novel Approach to Serine Protease Inhibition: Kinetic Characterization of Inhibitors Whose Potencies and Selectivities Are Dramatically Enhanced by Zinc(II)

Biochemistry (Easton), 2000-04, Vol.39 (16), p.4792-4800

2000

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Expression, Crystallization, and Three-dimensional Structure of the Catalytic Domain of Human Plasma Kallikrein

Development of Serine Protease Inhibitors Displaying a Multicentered Short (<2.3 Å) Hydrogen Bond Binding Mode: Inhibitors of Urokinase-Type Plasminogen Activator and Factor Xa

The Structure of the Extracellular Region of Human Hepsin Reveals a Serine Protease Domain and a Novel Scavenger Receptor Cysteine-Rich (SRCR) Domain

Binding to Protein Targets of Peptidic Leads Discovered by Phage Display: Crystal Structures of Streptavidin-Bound Linear and Cyclic Peptide Ligands Containing the HPQ Sequence

Design of potent selective zinc-mediated serine protease inhibitors

Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH

Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases

Discovery of novel heterocyclic factor VIIa inhibitors

Factor VIIa inhibitors: Chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in an arterial baboon thrombosis model

Efficiency of signalling through cytokine receptors depends critically on receptor orientation

Exploiting Subsite S1 of Trypsin-Like Serine Proteases for Selectivity: Potent and Selective Inhibitors of Urokinase-Type Plasminogen Activator

Promoter polymorphism of the erythropoietin gene in severe diabetic eye and kidney complications

Peripapillary Ovoid Hyperreflectivity in Optic Disc Edema and Pseudopapilledema

A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site

Update on blepharospasm: report from the BEBRF International Workshop

Structure-Guided Design of Peptide-Based Tryptase Inhibitors

Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-directed Serine Protease Inhibitors

Factor VIIa inhibitors: Gaining selectivity within the trypsin family

The Idiopathic Intracranial Hypertension Treatment Trial: Design Considerations and Methods

Factor VIIa inhibitors: Improved pharmacokinetic parameters

Contribution of Multicentered Short Hydrogen Bond Arrays to Potency of Active Site-Directed Serine Protease Inhibitors

Structure-based design of high affinity streptavidin binding cyclic peptide ligands containing thioether crosslinks

2-(2-Hydroxy-3-alkoxyphenyl)-1H-benzimidazole-5-carboxamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors

4-Aminoarylguanidine and 4-aminobenzamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors

A Novel Approach to Serine Protease Inhibition: Kinetic Characterization of Inhibitors Whose Potencies and Selectivities Are Dramatically Enhanced by Zinc(II)

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